Gene Information

Name : Mic7113_2645 (Mic7113_2645)
Accession : YP_007121839.1
Strain : Microcoleus sp. PCC 7113
Genome accession: NC_019738
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : -
COG ID : -
EC number : 2.7.1.40
Position : 3043326 - 3045107 bp
Length : 1782 bp
Strand : +
Note : PFAM: Pyruvate kinase, barrel domain; PEP-utilising enzyme, mobile domain; Pyruvate kinase, alpha/beta domain

DNA sequence :
ATGCAATTGCGAAATTCCTTGCGTCGGACAAAGATTGTTGCCACGATTGGCCCCGCCTCCAGCCAACCTGATGTGCTGAA
AGCCCTGATTAAAGCCGGTGCCACCACACTACGGCTCAACTTTTCTCATGGCACTCATGAAGATCACCAGCGTAGTATCC
GTCTGATTCGCCAAACCGCCTTTGAACTCAATCAACCCGTCGGCATTTTACAAGACTTGCAAGGGCCGAAAATTCGCCTG
GGGCGGTTTGAGAACGGTTCGATTGTCCTCAACAAAGGCGATTGCTTTACCTTAACCAGCCTTCCTGTCCCAGGTAACCA
GGAAATCAGTTCGGTCACCTACGAACCCCTCGCCGACGAAGTTCCCTGCGGGGCCAACATTCTCTTAGACGATGGCAGAG
TCGAGATGCGAGTCGAAGAAGTAGACCGCAAAAACCGTGCCTTGCACTGTCGCGTTGTTGTGGGTGGACCCCTTTCCAAT
AACAAAGGCGTCAACTTTCCCGGCGTCTACCTCTCGATTAAAGCGATGACGGATAAAGACCGACAGGATTTAATGTTTGG
TCTGGATCAAGGGGTAGATTGGGTTGCTCTCAGCTTTGTCCGCAACCCCCAAGACGTGCTGGAAATTAAAGAACTGATTG
CCAGTGCGGGCAAGCAAACCCCCGTCATTGTCAAGATTGAAAAGCACGAAGCCATTGAGCAAATGGAGGCGATTCTCTCG
CTTTCAGATGGCGTTATGGTTGCTAGAGGTGACTTAGGCGTTGAACTGCCTGCGGAAGATGTCCCGATTTTGCAAAAGCG
GCTGATTGCCACGGCTAACCGACTGGGAATTCCGGTGATCACCGCCACCCAGATGCTAGACAGCATGGTGAACTCGCCTC
GACCCACCCGTGCTGAGATTTCTGATGTCGCCAATGCGATTCTCGATGGTACTGATGCTGTGATGCTCTCCAATGAAGCG
GCTGTCGGAAAATACCCCGTTGAAGCGGTGGAGACAATGGCGCGGATTGCCGTGCGGATTGAGCAAGAACAAATTTCTAG
CAATATCAAGGATACCAAGCGTTCCATTCCTAACGCCATTTCTCAGGCAGTGGGTCAAATTGCCGAACAGTTGCAGGCGG
CAGCGATTATGACCTTGACCAAGACTGGGTCAACGGCACGCAACGTCTCGAAGTTCCGACCCACTACACCGATTCTCGCC
ATCACCCCTCATGTGGATGTAGCGCGACAGCTCCAACTGGTATGGGGTGTCAAACCCTTGTTGGTGCTGGATTTACCCTC
AACGGGTCAGACCTTCCAAGCGGCGATTAATGTCGCTCAAGAAAAGCTGCTGCTGGCAGAAGGTGATTTAGTGGTGATGA
CGGCGGGAACACTCCAAGGCGTTCCGGGGTCAACAGATTTGATCAAAGTCGAGGTCGTGACTGCCGTTCTCGGTCAAGGC
ATTGGCATCGGTCAAGGTTCTGTCAGCGGACTCGCCCGCGTCGCCCACAGCGCTATGGATATTGGGAACTTCAACCCTGG
AGAAATTCTGGTGGCATCATCAACGAATGCTGATTTTGTCGAAGCCATCCGCAAGGCAGCAGGAATTATTACAGAAGAAG
GAAGTTTAACCAGCCATGCGGCAGTCATCGGTATGCGTTTGGGTGTGCCGGTAATTGTGGGGGTTAAAAATGCCACGCAA
ATGATTCGGGATGGGGCAATTTTAACGATGGATACCCCGCGAGGATTAGTTTATTCCGGTGCGATGGGTGCAAGCCCTGC
TAGTGGAATGCTGATGGTTTAG

Protein sequence :
MQLRNSLRRTKIVATIGPASSQPDVLKALIKAGATTLRLNFSHGTHEDHQRSIRLIRQTAFELNQPVGILQDLQGPKIRL
GRFENGSIVLNKGDCFTLTSLPVPGNQEISSVTYEPLADEVPCGANILLDDGRVEMRVEEVDRKNRALHCRVVVGGPLSN
NKGVNFPGVYLSIKAMTDKDRQDLMFGLDQGVDWVALSFVRNPQDVLEIKELIASAGKQTPVIVKIEKHEAIEQMEAILS
LSDGVMVARGDLGVELPAEDVPILQKRLIATANRLGIPVITATQMLDSMVNSPRPTRAEISDVANAILDGTDAVMLSNEA
AVGKYPVEAVETMARIAVRIEQEQISSNIKDTKRSIPNAISQAVGQIAEQLQAAAIMTLTKTGSTARNVSKFRPTTPILA
ITPHVDVARQLQLVWGVKPLLVLDLPSTGQTFQAAINVAQEKLLLAEGDLVVMTAGTLQGVPGSTDLIKVEVVTAVLGQG
IGIGQGSVSGLARVAHSAMDIGNFNPGEILVASSTNADFVEAIRKAAGIITEEGSLTSHAAVIGMRLGVPVIVGVKNATQ
MIRDGAILTMDTPRGLVYSGAMGASPASGMLMV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 6e-86 45
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 4e-86 45
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 4e-86 45
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 5e-86 45
pykA NP_273151.1 pyruvate kinase Not tested IHT-A Protein 8e-64 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mic7113_2645 YP_007121839.1 pyruvate kinase VFG0479 Protein 2e-86 45