Gene Information

Name : Osc7112_3801 (Osc7112_3801)
Accession : YP_007116559.1
Strain : Oscillatoria nigro-viridis PCC 7112
Genome accession: NC_019729
Putative virulence/resistance : Resistance
Product : Chloramphenicol O-acetyltransferase
Function : -
COG functional category : -
COG ID : -
EC number : 2.3.1.28
Position : 4508721 - 4509353 bp
Length : 633 bp
Strand : +
Note : PFAM: Bacterial transferase hexapeptide (three repeats); COGs: COG0110 Acetyltransferase (isoleucine patch superfamily); KEGG: syn:sll1900 acetyltransferase; PRIAM: Chloramphenicol O-acetyltransferase; SPTR: Streptogramin A acetyltransferase

DNA sequence :
ATGACAGAAATTGGGCCAGATCCAAACCGACCCTATCCGATGGCCGACCAAAGGCGCGTATGCTTCATCAAAAACTTTAT
TAAATCCCCCAACATTATCGTCGGCGATTACTCCTATTATGACGATCCAATAGAGCCAGAAAACTTTGAAAGAAATGTAC
TTTATAACTACGGAAACGATCGATTAATTATTGGCAAATTTTGTGCGATCGCCACCAATGTCAAATTCATTATGAACGGT
GCAAATCACAAACTAGACGGCATTTCAACTTATCCTTTTCCGGTTTTTGGTAATGGTTGGGAAACAGCCATGAATTTAGT
AATGGAACTGCCAAGTAAAGGCGATACCGTCATTGGCAATGATGTTTGGCTCGGCTATGAATCCCTGATTATGCCTGGAG
TCAAAATCGGCGACGGTGCCGTCATTGCCGCCAAATCCGTTGTAGTAAAAGACATTCCCGCTTACACCGTTGTGGGCGGA
AACCCCGCCCATCCAATCAAACAGCGTTTTAGCGATGGTGAAGTTGCACAACTATTAGAAATTCGGTGGTGGGATTGGGA
AATCGACAAGATTTCGCGCCATGTCAGCATAATTATGCAAGGCGATATTCAAGCACTCAAAAATGCCGAGTAA

Protein sequence :
MTEIGPDPNRPYPMADQRRVCFIKNFIKSPNIIVGDYSYYDDPIEPENFERNVLYNYGNDRLIIGKFCAIATNVKFIMNG
ANHKLDGISTYPFPVFGNGWETAMNLVMELPSKGDTVIGNDVWLGYESLIMPGVKIGDGAVIAAKSVVVKDIPAYTVVGG
NPAHPIKQRFSDGEVAQLLEIRWWDWEIDKISRHVSIIMQGDIQALKNAE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
catB8 YP_005797132.1 chloramphenicol acetyltransferase Not tested AbaR4e Protein 5e-30 47
catB3 AET25385.1 chloramphenicol acetyltransferase Not tested PAGI-2(C) Protein 1e-30 41
catB3 AFG30108.1 chloramphenicol acetyltransferase Not tested PAGI-2 Protein 1e-30 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Osc7112_3801 YP_007116559.1 Chloramphenicol O-acetyltransferase AM180355.1.gene2499. Protein 1e-47 48
Osc7112_3801 YP_007116559.1 Chloramphenicol O-acetyltransferase AY123251.gene2.p01 Protein 2e-30 47
Osc7112_3801 YP_007116559.1 Chloramphenicol O-acetyltransferase NC_002516.2.878374.p Protein 4e-30 43
Osc7112_3801 YP_007116559.1 Chloramphenicol O-acetyltransferase JF268688.1.gene6.p01 Protein 1e-29 42
Osc7112_3801 YP_007116559.1 Chloramphenicol O-acetyltransferase CP001581.1.gene990.p Protein 6e-33 41
Osc7112_3801 YP_007116559.1 Chloramphenicol O-acetyltransferase AY740681.1.gene5.p01 Protein 6e-31 41
Osc7112_3801 YP_007116559.1 Chloramphenicol O-acetyltransferase AF322577.2.gene4.p01 Protein 6e-31 41