Gene Information

Name : Lepto7376_4331 (Lepto7376_4331)
Accession : YP_007073273.1
Strain : Leptolyngbya sp. PCC 7376
Genome accession: NC_019683
Putative virulence/resistance : Unknown
Product : hydroxymethylbilane synthase
Function : -
COG functional category : -
COG ID : -
EC number : 2.5.1.61
Position : 4836734 - 4837699 bp
Length : 966 bp
Strand : -
Note : PFAM: Porphobilinogen deaminase, C-terminal domain; Porphobilinogen deaminase, dipyromethane cofactor binding domain; TIGRFAM: porphobilinogen deaminase; COGs: COG0181 Porphobilinogen deaminase; HAMAP: Tetrapyrrole biosynthesis, hydroxymethylbilane syntha

DNA sequence : 
ATGACCGCTGTGACCACCCCTAAACGTACTGTAAAAATTGGTTCCCGTAAGAGTCAACTGGCGTTGGTTCAGACCTATTG
GGTACGTGACGAATTGCAAAAAGCTTACCCTGACATCAAGTTTGAAGTACAGACCATGGAAACCCAGGGCGACAAAGTAC
TTGATGTTGCTCTCTCGAAAATTGGTGATAAGGGACTGTTTACCCAAGAACTTGAAGATGGAATGCTCAAGCGGGAAACT
GATTTTGCGGTACATTCCCTCAAAGATTTGCCAACAAATCTTCCCGAAGGTTTGATGCTGGGTTGTGTCACAGAGCGCGT
TGATCCCGCTGATGCCCTTGTAGTTCATGAAAAGCATAAGGACAAGAAGTTAGCGACCTTACCCGAAGGCGCAATTATTG
GTACGTCTTCTCTCCGTCGCCTCGCACAACTCCGGCACCATTATCCTCATCTCGAATTTAAGGATATCCGTGGTAATGTC
AACACTCGTCTTGCGAAGCTTGATAGCGGTGACTATGACGCGATTATTTTGGCCGCAGCGGGCCTACAACGTCTTGATTT
TGGCGATCGCATCCACCAGATTATTCCCAGCGATATTTCCCTCCACGCTGTAGGTCAAGGGGCACTCGGTATTGAATGTC
GTGATGGCGATACTGAAATCCTTGAATTGTTACGTCCTGTTCTCGAACATATTGAAAGCCGTGATCGTTGCTATGCAGAG
CGAGCATTTTTGCGTGAACTTGAAGGTGGTTGTCAGGTACCGATTGGCGTAAATACAACAATTGATGGCGATAATATACT
TCTCGTTGGTATGGTTGCAAGTCTTGATGGCAAGACCCTACTTCGCGATGAAGTTAGTGGTAGTCGCGCTGATGCTGAAA
AGTTAGGTGTTCAGCTTGCTGAGAAAGTTGTTGCTCAGGGCGCGGATAAAATTCTCGCTGAAATTAATGAAGTTAACCGC
TCTTAA

Protein sequence : 
MTAVTTPKRTVKIGSRKSQLALVQTYWVRDELQKAYPDIKFEVQTMETQGDKVLDVALSKIGDKGLFTQELEDGMLKRET
DFAVHSLKDLPTNLPEGLMLGCVTERVDPADALVVHEKHKDKKLATLPEGAIIGTSSLRRLAQLRHHYPHLEFKDIRGNV
NTRLAKLDSGDYDAIILAAAGLQRLDFGDRIHQIIPSDISLHAVGQGALGIECRDGDTEILELLRPVLEHIESRDRCYAE
RAFLRELEGGCQVPIGVNTTIDGDNILLVGMVASLDGKTLLRDEVSGSRADAEKLGVQLAEKVVAQGADKILAEINEVNR
S

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 1e-62 51
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 1e-62 51