Gene Information

Name : Lepto7376_4143 (Lepto7376_4143)
Accession : YP_007073102.1
Strain : Leptolyngbya sp. PCC 7376
Genome accession: NC_019683
Putative virulence/resistance : Virulence
Product : iron-chelate-transporting ATPase
Function : -
COG functional category : -
COG ID : -
EC number : 3.6.3.34
Position : 4608800 - 4609639 bp
Length : 840 bp
Strand : +
Note : PFAM: ABC transporter; COGs: COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components; InterPro IPR003593:IPR003439; KEGG: amr:AM1_A0161 iron(III) dicitrate ABC transporter; PFAM: ABC transporter-like; PRIAM: Iron-chelate-transport

DNA sequence :
ATGCACTCCCCAACCCTCACTGACATGCCACAGGCGATCGCCCTCACGACTCGCAAACTTACCATTGCGTACGATAGCAA
AATAATTATTGACGAGCTTGATTTAGCTATTCCCAAAGGAAAAATCACAATCCTTGTGGGTCCTAATGGTTGCGGAAAAT
CAACACTTCTCAAAGGCCTGGGACGTTTACTCAAACCACAATCCGGTGTTGTTTATCTTGACAGCAAATCCATTTTCAAA
TTACCAACCAAAGCAGTGGCAAAACAGTTGGGTTTATTGCCCCAAAGCCCTACTGCCCCCGAAGGCTTAACCGTTAGAGA
GTTAGTTGCTCAGGGTCGTTATCCTTATCAGAGTTGGATACAACAATGGAGTGCAGAAGACGAGAAACAAGTTGAACTTG
CTCTTGCCGAAACCGAATTACAAGAGTTGGCAGGTCGTGCCGTTGATAGCCTATCAGGAGGTCAGAGACAACGAGCATGG
GTTGCGATGACTCTGGCCCAGAATACTCGAATTTTATTGCTAGATGAACCCACAACTTTTCTTGATTTAGCCCACCAAAT
CGAGGTTTTAGACCTACTCTATGATCTTAACCAACGGGAAGGCCGCACTGTCGTTATGGTTTTACATGAACTCAATCAAG
CTTGTCGATATGCGGATCATATTATTGCGATGCGATTAGGGAAGGTCTATGCTCAAGGTGAGCCCCATAATGTGATGACA
GAAGGATTAGTGAAAACAGTTTTTGGTCTAGATTGCCGTATTATTAAAGACCCTTTGGCAGGGACACCACTTTGCATTCC
AATGGGTCGTAAAGTAGCGACACTAGAACATCAGCATTGA

Protein sequence :
MHSPTLTDMPQAIALTTRKLTIAYDSKIIIDELDLAIPKGKITILVGPNGCGKSTLLKGLGRLLKPQSGVVYLDSKSIFK
LPTKAVAKQLGLLPQSPTAPEGLTVRELVAQGRYPYQSWIQQWSAEDEKQVELALAETELQELAGRAVDSLSGGQRQRAW
VAMTLAQNTRILLLDEPTTFLDLAHQIEVLDLLYDLNQREGRTVVMVLHELNQACRYADHIIAMRLGKVYAQGEPHNVMT
EGLVKTVFGLDCRIIKDPLAGTPLCIPMGRKVATLEHQH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
fecE AAL08451.1 ATP-binding protein FecE Virulence SRL Protein 8e-57 50
fagC YP_005680307.1 ATP binding cytoplasmic membrane protein Not tested PiCp 1 Protein 4e-59 49
fagC YP_003782430.1 ABC transporter ATP-binding protein Not tested PiCp 1 Protein 4e-59 49
fagC YP_005682397.1 ATP binding cytoplasmic membrane protein Virulence PiCp 1 Protein 3e-59 49
fagC YP_005684488.1 ATP binding cytoplasmic membrane protein Not tested PiCp 1 Protein 3e-59 49
iusE YP_005143742.1 iron ABC transporter ATP-binding protein Virulence Not named Protein 9e-59 48
SP_1035 NP_345510.1 iron-compound ABC transporter ATP-binding protein Not tested PPI-1 Protein 2e-58 48
SPN23F_09560 YP_002510939.1 ferric siderophore ABC transporter ATP-binding protein Virulence PPI-1 Protein 2e-58 48
DIP0585 NP_938961.1 iron ABC transporter ATP-binding protein Virulence Not named Protein 2e-56 46
ciuD YP_005681255.1 Iron ABC transporter ATP-binding protein Virulence PiCp 4 Protein 2e-54 45
ciuD YP_005683346.1 Iron ABC transporter ATP-binding protein Virulence PiCp 4 Protein 2e-54 45
ciuD YP_003783391.1 iron ABC transporter ATP-binding protein Virulence PiCp 4 Protein 2e-54 45
ciuD YP_005685432.1 Iron ABC transporter ATP-binding protein Virulence PiCp 4 Protein 2e-54 45

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Lepto7376_4143 YP_007073102.1 iron-chelate-transporting ATPase BAC0164 Protein 5e-57 50

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Lepto7376_4143 YP_007073102.1 iron-chelate-transporting ATPase VFG0925 Protein 8e-65 51
Lepto7376_4143 YP_007073102.1 iron-chelate-transporting ATPase VFG1042 Protein 4e-57 50