Gene Information

Name : Lepto7376_4129 (Lepto7376_4129)
Accession : YP_007073092.1
Strain : Leptolyngbya sp. PCC 7376
Genome accession: NC_019683
Putative virulence/resistance : Virulence
Product : winged helix family two component transcriptional regulator
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 4598241 - 4598969 bp
Length : 729 bp
Strand : -
Note : PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: syp:SYNPCC7002

DNA sequence :
TTGGAAAATCATAAAGAAAGAATTCTCGTCGTTGACGATGAAGCGAGCATTCGACGTATCCTCGAAACTCGTCTTTCCAT
GATTGGTTACGAGGTAGTCACCGCAGCCGACGGCGAAGAAGCATTAGGAACCTTTACAGACGCAGATCCAGATTTGGTTG
TGCTCGATGTCATGATGCCGAAGCTCGATGGCTATGGCGTCTGCCAGGAACTCCGTAAAGAGTCCGATGTCCCTATTATT
ATGCTCACAGCTCTTGGTGACGTTGCTGATCGAATTACTGGTTTGGAGCTTGGGGCCGACGATTATGTCGTGAAGCCTTT
CTCTCCTAAGGAATTAGAAGCAAGGATTCGTTCTGTACTGCGCCGCGTTGACAAGAATGGGATTACTGGTATTCCTAGTT
CTGGCGTCATTCACGTCGGTTCTATTCGTATCGATACCAACAAGCGTCAAGTCTATAAAGGTGATGAGCGCATCCGCCTC
ACAGGTATGGAATTCAGCCTACTTGAGCTATTAGTTAGCCGATCTGGTGAACCTTTCTCCCGTTCAGAAATCCTTCAAGA
AGTTTGGGGCTATACCCCTGAACGTCATGTGGATACTCGTGTTGTGGATGTTCACATTTCGCGACTCAGAGCCAAGCTTG
AAGATGACCCGAGTAATCCAGAGCTGATTTTGACTGCGCGTGGAACTGGCTATCTTTTCCAACGTATTCTCGAACCAGGT
GATGAGTAA

Protein sequence :
MENHKERILVVDDEASIRRILETRLSMIGYEVVTAADGEEALGTFTDADPDLVVLDVMMPKLDGYGVCQELRKESDVPII
MLTALGDVADRITGLELGADDYVVKPFSPKELEARIRSVLRRVDKNGITGIPSSGVIHVGSIRIDTNKRQVYKGDERIRL
TGMEFSLLELLVSRSGEPFSRSEILQEVWGYTPERHVDTRVVDVHISRLRAKLEDDPSNPELILTARGTGYLFQRILEPG
DE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
copR NP_460069.2 transcriptional regulatory protein YedW Not tested SPI-5 Protein 3e-30 42
CDB402_0209 YP_005126722.1 two-component system response regulator Not tested Not named Protein 3e-36 41
copR AAC33719.1 regulatory protein CopR Not tested SPI-5 Protein 1e-29 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Lepto7376_4129 YP_007073092.1 winged helix family two component transcriptional regulator NC_002952.2859905.p0 Protein 1e-47 50
Lepto7376_4129 YP_007073092.1 winged helix family two component transcriptional regulator NC_002951.3237708.p0 Protein 2e-47 50
Lepto7376_4129 YP_007073092.1 winged helix family two component transcriptional regulator NC_002758.1121668.p0 Protein 2e-47 50
Lepto7376_4129 YP_007073092.1 winged helix family two component transcriptional regulator NC_009641.5332272.p0 Protein 2e-47 50
Lepto7376_4129 YP_007073092.1 winged helix family two component transcriptional regulator NC_013450.8614421.p0 Protein 2e-47 50
Lepto7376_4129 YP_007073092.1 winged helix family two component transcriptional regulator NC_007793.3914279.p0 Protein 2e-47 50
Lepto7376_4129 YP_007073092.1 winged helix family two component transcriptional regulator NC_003923.1003749.p0 Protein 2e-47 50
Lepto7376_4129 YP_007073092.1 winged helix family two component transcriptional regulator NC_007622.3794472.p0 Protein 9e-48 50
Lepto7376_4129 YP_007073092.1 winged helix family two component transcriptional regulator NC_002745.1124361.p0 Protein 2e-47 50
Lepto7376_4129 YP_007073092.1 winged helix family two component transcriptional regulator NC_009782.5559369.p0 Protein 2e-47 50
Lepto7376_4129 YP_007073092.1 winged helix family two component transcriptional regulator BAC0125 Protein 4e-39 46
Lepto7376_4129 YP_007073092.1 winged helix family two component transcriptional regulator AE000516.2.gene3505. Protein 3e-43 46
Lepto7376_4129 YP_007073092.1 winged helix family two component transcriptional regulator NC_012469.1.7685629. Protein 8e-43 46
Lepto7376_4129 YP_007073092.1 winged helix family two component transcriptional regulator HE999704.1.gene2815. Protein 1e-41 46
Lepto7376_4129 YP_007073092.1 winged helix family two component transcriptional regulator CP000034.1.gene3671. Protein 3e-39 44
Lepto7376_4129 YP_007073092.1 winged helix family two component transcriptional regulator CP001918.1.gene5135. Protein 4e-25 43
Lepto7376_4129 YP_007073092.1 winged helix family two component transcriptional regulator BAC0638 Protein 2e-28 43
Lepto7376_4129 YP_007073092.1 winged helix family two component transcriptional regulator BAC0083 Protein 7e-36 42
Lepto7376_4129 YP_007073092.1 winged helix family two component transcriptional regulator BAC0197 Protein 9e-34 42
Lepto7376_4129 YP_007073092.1 winged helix family two component transcriptional regulator NC_007622.3794948.p0 Protein 5e-36 41
Lepto7376_4129 YP_007073092.1 winged helix family two component transcriptional regulator NC_003923.1003417.p0 Protein 5e-36 41
Lepto7376_4129 YP_007073092.1 winged helix family two component transcriptional regulator NC_013450.8614146.p0 Protein 5e-36 41
Lepto7376_4129 YP_007073092.1 winged helix family two component transcriptional regulator NC_002951.3238224.p0 Protein 5e-36 41
Lepto7376_4129 YP_007073092.1 winged helix family two component transcriptional regulator NC_007793.3914065.p0 Protein 5e-36 41
Lepto7376_4129 YP_007073092.1 winged helix family two component transcriptional regulator NC_002758.1121390.p0 Protein 5e-36 41
Lepto7376_4129 YP_007073092.1 winged helix family two component transcriptional regulator NC_010079.5776364.p0 Protein 5e-36 41
Lepto7376_4129 YP_007073092.1 winged helix family two component transcriptional regulator NC_002952.2859858.p0 Protein 5e-36 41
Lepto7376_4129 YP_007073092.1 winged helix family two component transcriptional regulator BAC0308 Protein 1e-36 41
Lepto7376_4129 YP_007073092.1 winged helix family two component transcriptional regulator CP000675.2.gene1535. Protein 2e-37 41
Lepto7376_4129 YP_007073092.1 winged helix family two component transcriptional regulator CP001485.1.gene721.p Protein 6e-34 41
Lepto7376_4129 YP_007073092.1 winged helix family two component transcriptional regulator CP004022.1.gene3215. Protein 4e-34 41
Lepto7376_4129 YP_007073092.1 winged helix family two component transcriptional regulator NC_002695.1.915041.p Protein 9e-28 41
Lepto7376_4129 YP_007073092.1 winged helix family two component transcriptional regulator CP000647.1.gene4257. Protein 1e-28 41
Lepto7376_4129 YP_007073092.1 winged helix family two component transcriptional regulator NC_012469.1.7686381. Protein 8e-41 41
Lepto7376_4129 YP_007073092.1 winged helix family two component transcriptional regulator CP000034.1.gene3834. Protein 9e-28 41
Lepto7376_4129 YP_007073092.1 winged helix family two component transcriptional regulator BAC0533 Protein 1e-28 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Lepto7376_4129 YP_007073092.1 winged helix family two component transcriptional regulator VFG1389 Protein 9e-34 45
Lepto7376_4129 YP_007073092.1 winged helix family two component transcriptional regulator VFG1390 Protein 2e-39 44
Lepto7376_4129 YP_007073092.1 winged helix family two component transcriptional regulator VFG0596 Protein 1e-30 42