Gene Information

Name : Lepto7376_3156 (Lepto7376_3156)
Accession : YP_007072223.1
Strain : Leptolyngbya sp. PCC 7376
Genome accession: NC_019683
Putative virulence/resistance : Resistance
Product : chloramphenicol O-acetyltransferase
Function : -
COG functional category : -
COG ID : -
EC number : 2.3.1.28
Position : 3485055 - 3485690 bp
Length : 636 bp
Strand : +
Note : PFAM: Bacterial transferase hexapeptide (three repeats); COGs: COG0110 Acetyltransferase (isoleucine patch superfamily); KEGG: syf:Synpcc7942_0704 chloramphenicol O-acetyltransferase; PRIAM: Chloramphenicol O-acetyltransferase; SPTR: Acetyltransferase

DNA sequence :
ATGAATTATCCCGATCCGCGACAGGTACATCCCCTACCGAATTTTCCGCAGGTTTGTTTCATCAAAAACACGGTCAAAAA
TCCCCAAATCATCATTGGTGACTATACCTATTGCGATGACCCAGAAGATTCGGAGAATTTCGAGCGCAATGTTCTCTATC
TATTTCCCTTTGTTGGTGATCGCCTAATTATCGGAAAGTTTTGTGCGATCTCCCGCGGTGTGACATTCATCATGAATGGT
GCGAACCATAAAATGTCTGGATTTTCGACCTATCCCTTTGAGATCTTTGGAGAAGATTGGGCGCGGGTCATGCCGAAGCA
AGAAGAATATCCCAACAAAGGCGACACGATAATTGGCAATGATGTGTGGATTGGCTATGAAAGTGTGATTATGCCGGGCA
TCAAAATCGGTCATGGTTCCATTATCGCGGCGAAATCAGTGGTCACAAAGGATGTGCCAGCCTATGGTGTTGTGGGTGGA
AATCCAGCCAAACTCATTCGTAAACGATTCGATGATCAAGTGATTGAGTCACTCGAAAAAATTGCTTGGTGGGATTGGGA
TATACAAAAAATCACCGACAATCTGGAGGCGATCGCCGGTAATAATTTAGACATTTTGAAAAGTCTTAACTGCTAA

Protein sequence :
MNYPDPRQVHPLPNFPQVCFIKNTVKNPQIIIGDYTYCDDPEDSENFERNVLYLFPFVGDRLIIGKFCAISRGVTFIMNG
ANHKMSGFSTYPFEIFGEDWARVMPKQEEYPNKGDTIIGNDVWIGYESVIMPGIKIGHGSIIAAKSVVTKDVPAYGVVGG
NPAKLIRKRFDDQVIESLEKIAWWDWDIQKITDNLEAIAGNNLDILKSLNC

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
catB3 AET25385.1 chloramphenicol acetyltransferase Not tested PAGI-2(C) Protein 2e-31 42
catB3 AFG30108.1 chloramphenicol acetyltransferase Not tested PAGI-2 Protein 2e-31 42
catB8 YP_005797132.1 chloramphenicol acetyltransferase Not tested AbaR4e Protein 5e-30 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Lepto7376_3156 YP_007072223.1 chloramphenicol O-acetyltransferase AM180355.1.gene2499. Protein 1e-43 47
Lepto7376_3156 YP_007072223.1 chloramphenicol O-acetyltransferase AY740681.1.gene5.p01 Protein 9e-32 42
Lepto7376_3156 YP_007072223.1 chloramphenicol O-acetyltransferase AF322577.2.gene4.p01 Protein 9e-32 42
Lepto7376_3156 YP_007072223.1 chloramphenicol O-acetyltransferase JF268688.1.gene6.p01 Protein 2e-33 42
Lepto7376_3156 YP_007072223.1 chloramphenicol O-acetyltransferase AY123251.gene2.p01 Protein 2e-30 42