Gene Information

Name : Lepto7376_0258 (Lepto7376_0258)
Accession : YP_007069536.1
Strain : Leptolyngbya sp. PCC 7376
Genome accession: NC_019683
Putative virulence/resistance : Virulence
Product : urease
Function : -
COG functional category : -
COG ID : -
EC number : 3.5.1.5
Position : 299027 - 300739 bp
Length : 1713 bp
Strand : -
Note : PFAM: Urease alpha-subunit, N-terminal domain; Amidohydrolase family; TIGRFAM: urease, alpha subunit; COGs: COG0804 Urea amidohydrolase (urease) alpha subunit; HAMAP: Urease, alpha subunit; InterPro IPR005848:IPR011612:IPR006680; KEGG: ter:Tery_0752 ureas

DNA sequence :
ATGAGTTACCGTATGAATCGCCGCTCCTACGCCGATACCTTTGGCCCCACCGTTGGCGATCGCGTTCGTTTGGCGGATAC
CGAATTATTTATCGAAGTCGAGCGGGACTACACAACCTACGGTGACGAGGTGAAATTCGGCGGAGGTAAAGTTATCCGCG
ATGGTATGGGGCAATCGCCAATTTCTCGGGAAGATGGCGCGGTAGATATGGTGATCACTAATGCCCTAATCCTTGATTGG
TGGGGCGTTGTGAAAGCGGATATTGGCATCAAGGACGGCAAAATCCACAAAATTGGCAAAGCTGGAAACCCTTATATTCA
AGACGATGTTGACATTATTATTGGCCCCGCAACCGAAGCTGTTGCTGGCGAAGGTCATATTGTCACAGCGGGTGGCATTG
ATAGCCACATTCACTTTATTTGTCCCCAACAAATCGAAACGGCGATCGCCTCTGGGATCACAACGATGATTGGTGGCGGA
ACTGGCCCAGCAACGGGGACCAATGCAACCACTTGTACGCCTGGCCAATGGAATATCTGGATGATGCTGCAAGCGGCCGA
TGCCTTCCCGATGAATTTAGGTTTTTTGGGAAAAGGCAATAGTAGTCAACCTCAAGGCTTAGTTGAACAAGTGAAAGCTG
GTGCGATGGGATTAAAACTCCATGAAGATTGGGGCACAACTCCGGCGGCGATCGATACTTGTTTGGATGTTGCCGATGAA
TATGATATCCAAGTTGCCATCCACACCGACACGCTTAACGAAGCAGGCTTTGTTGAAAATACCGTTGCCGCTTTCAAAGA
CCGGGTAATCCATACCTATCACACGGAAGGCGCTGGTGGTGGACATGCCCCAGACATCATCAAAGTGTGTAGCTATAGCA
ATGTTTTACCCTCTTCGACTAATCCAACCCGGCCTTTTACCGTTAATACTCTGGAAGAGCATTTGGATATGTTGATGGTG
TGTCACCACCTCGACAAAAATATTCCTGAAGATGTAGCCTTTGCCGAATCCCGGATTCGTCGCGAAACCATTGCTGCCGA
AGATATTTTGCATGACTTGGGTGCTTTTAGTGCGATCGCCTCTGATTCCCAAGCGATGGGTCGCGTTGGTGAAACCATTA
TTCGCACTTGGCAAACTGCCCACAAAATGAAAGTTCAACGAGGTGTGCTCTCTTCCCCAACCACTGAAGTTGCCGATAAT
TTCCGCGCTAAACGCTATGTCGCTAAATACACCATCAATCCTGCAATTATGCACGGGATCGCTGACCATGTGGGTTCTTT
AGAAGAAGGCAAGCTCGCAGACATTTGCCTCTGGAAACCTGCCATGTTTGGCGTTAAACCCGAAATTGTCATCAAAGGTG
GGGCGATCGCCTGGGCACAGATGGGAGATCCCAATGCCAGTATCCCCACCCCTCAACCCATCTATATGCGTCCAATGTTT
GGGAGTTTTGGTGGCGCAACAGCACCAACATCCCTGACTTTCGTTTCCCAAGCTTCATTAGAATTGGGTATTCCAGACCA
AATTGGTATTAAAACCCCTGCCGTTGCCGTGAGCAATACCCGCAAGATTAGCAAAGCTGACATGAAGCTCAACGATGCAA
CCCCCAATGTCGAAGTTAATCCCGAAACTTATGAAGTGAAAGCAGATGGTGAATTGTTGACTTGTGAACCGGCTGATGTT
TTACCAATGGCACAGCGTTATTTTCTGTTTTAA

Protein sequence :
MSYRMNRRSYADTFGPTVGDRVRLADTELFIEVERDYTTYGDEVKFGGGKVIRDGMGQSPISREDGAVDMVITNALILDW
WGVVKADIGIKDGKIHKIGKAGNPYIQDDVDIIIGPATEAVAGEGHIVTAGGIDSHIHFICPQQIETAIASGITTMIGGG
TGPATGTNATTCTPGQWNIWMMLQAADAFPMNLGFLGKGNSSQPQGLVEQVKAGAMGLKLHEDWGTTPAAIDTCLDVADE
YDIQVAIHTDTLNEAGFVENTVAAFKDRVIHTYHTEGAGGGHAPDIIKVCSYSNVLPSSTNPTRPFTVNTLEEHLDMLMV
CHHLDKNIPEDVAFAESRIRRETIAAEDILHDLGAFSAIASDSQAMGRVGETIIRTWQTAHKMKVQRGVLSSPTTEVADN
FRAKRYVAKYTINPAIMHGIADHVGSLEEGKLADICLWKPAMFGVKPEIVIKGGAIAWAQMGDPNASIPTPQPIYMRPMF
GSFGGATAPTSLTFVSQASLELGIPDQIGIKTPAVAVSNTRKISKADMKLNDATPNVEVNPETYEVKADGELLTCEPADV
LPMAQRYFLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 2e-159 66
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 2e-159 66
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 4e-158 64
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 2e-159 63
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 2e-159 63
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 2e-159 63

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Lepto7376_0258 YP_007069536.1 urease VFG0270 Protein 3e-146 63