Gene Information

Name : Lepto7376_1233 (Lepto7376_1233)
Accession : YP_007070423.1
Strain : Leptolyngbya sp. PCC 7376
Genome accession: NC_019683
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : -
COG ID : -
EC number : 2.7.1.40
Position : 1376068 - 1377858 bp
Length : 1791 bp
Strand : -
Note : PFAM: Pyruvate kinase, barrel domain; PEP-utilising enzyme, mobile domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; COGs: COG0469 Pyruvate kinase; InterPro IPR015793:IPR015794:IPR008279:IPR001697; KEGG: syp:SYNPCC7002_A1658 pyruvate k

DNA sequence :
ATGGCCTTTAGAGACATGCCCCGCCGCACAAAAATCGTTGCAACAATCGGCCCAGCAACAAGCAAGCCCGATGTTCTGCG
CGAACTCATCGAAGCGGGAGCCACTACTCTACGGCTAAACTTCTCACACGGTACCCATGACGACCACCAGCGAAATATTC
GCCTTATTCGTCAAACAGCCTTTGAACTCAATTGTCCGGTCGGTATTCTTCAGGATTTACAAGGCCCGAAAATTCGCCTA
GGTAAATACGAAACAGGATCAATCCGTCTCAAGAAAAATGATCCTTATATCCTCACAAGTCGCCAAGTGCCCTGTACCCA
AGAAGTCGGGTATATCAGTTATCAAAAACTAGCAGCAGAAGTACCGGAGGGCGCAACCATTCTGCTTGATGATGGAAAAG
TTGAAATGCGCGTCGAGAAAATCGATGTGGAAGCCCAAAATCTTCATTGTCGCGTTGTCGTTGGTGGCACCCTCTCGAAC
AATAAAGGTGTTAATTTCCCCGGCGTTTACTTATCTGTTAAAGCCTTAACAGATAAAGACCGTGAAGACCTTATGTTTGG
TCTAGATCAAGGTGTTGATTGGGTCGCTCTCAGTTTTGTACGGAACCCAGAAGACGTATTAGAAATTAAAGGCATCATTG
CCGAAGCGGGGAAAAATGTCCCTGTCATCGTCAAAATCGAAAAACACGAAGCGATCGAACAGATGGATGCCATCCTCTCT
CTCTCTGATGGCGTAATGGTTGCGCGGGGTGACTTAGGTGTTGAATTGCCAGCAGAAGAAGTGCCACTCCTCCAGAAAAA
ATTGATTGCCACAGCTAACCGTCTTGGTATTCCTGTCATCACTGCGACACAGATGCTCGATAGTATGGCAAACAACCCTC
GTCCAACCCGTGCAGAAGTCTCTGACGTAGCGAACGCGATTCTTGATGGTACGGATGCCGTGATGCTCTCCAATGAAACC
GCTGTCGGCGAGTATCCCGTCGAATCGGTTGCAACCATGGCAACGATCGCCCGACGGATTGAGCAAGAGCCTGATGAGAT
TCGTCGTCAGCCTTCCGACAAAAAATCAATCCCCAATGCCATCTCCTCTGCGGTCAGTCATATCTCTAAACAACTGGATG
CTACTGCGATTATGACCCTCACAAAGTCTGGGGCAACGGCACGTAATGTTTCAAAATTCCGTCCTTTCACACCAATTTTG
GCAGTTACTCCCCATGTGGATGTCGCTCGTCGTTTGCAATTAGTTTGGGGGGCACAGCCTCTCCTCGTCATGGATTCTCC
CTCGACGACGCAAACCTTTAGAGCGGCGATTAATGTTGCTCAGGAAAAGGGGTTACTAAAAGAAGGTGATCTCGTAGTGA
TGACAGCAGGTACATTACAAGGTGTTTCTGGCTCCACTGACCTCGTAAAAGTTGAAGTCGTTCAGGCTGTTCTCGGTGCA
GGGACTGGCATCGGCCAAGGTTCAGCAAATGGTCGGGCACGGGTGGTTCAAGGAAATCAGGAAATCAATGATTTTAATAC
AGGGGATATTCTGGTGGCGGCGGCGACAGATGCCACTCATATCGATATGATTCGCAAAGCCGGTGGGGTAGTGATTGAAG
ATTTAAGTCAAAATTGTCACGCCGCAACGATTGGATTACGTCTCGGTATTCCGGTGATTGTTGGTTTCGATAACGCAACA
ACGTTAATTCGGGATGGTGGCATTATTTCTATCGATGCCCGTCGCGGTACGGTTTGTTCTGGTCTCAATGTCTCTCTTGG
TGATGCAGTAAAAAATTCGGCACTCTCCTAG

Protein sequence :
MAFRDMPRRTKIVATIGPATSKPDVLRELIEAGATTLRLNFSHGTHDDHQRNIRLIRQTAFELNCPVGILQDLQGPKIRL
GKYETGSIRLKKNDPYILTSRQVPCTQEVGYISYQKLAAEVPEGATILLDDGKVEMRVEKIDVEAQNLHCRVVVGGTLSN
NKGVNFPGVYLSVKALTDKDREDLMFGLDQGVDWVALSFVRNPEDVLEIKGIIAEAGKNVPVIVKIEKHEAIEQMDAILS
LSDGVMVARGDLGVELPAEEVPLLQKKLIATANRLGIPVITATQMLDSMANNPRPTRAEVSDVANAILDGTDAVMLSNET
AVGEYPVESVATMATIARRIEQEPDEIRRQPSDKKSIPNAISSAVSHISKQLDATAIMTLTKSGATARNVSKFRPFTPIL
AVTPHVDVARRLQLVWGAQPLLVMDSPSTTQTFRAAINVAQEKGLLKEGDLVVMTAGTLQGVSGSTDLVKVEVVQAVLGA
GTGIGQGSANGRARVVQGNQEINDFNTGDILVAAATDATHIDMIRKAGGVVIEDLSQNCHAATIGLRLGIPVIVGFDNAT
TLIRDGGIISIDARRGTVCSGLNVSLGDAVKNSALS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 8e-82 43
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 2e-81 43
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 2e-81 43
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 8e-82 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Lepto7376_1233 YP_007070423.1 pyruvate kinase VFG0479 Protein 3e-82 43