Gene Information

Name : Cal7507_5304 (Cal7507_5304)
Accession : YP_007068476.1
Strain : Calothrix sp. PCC 7507
Genome accession: NC_019682
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : -
COG ID : -
EC number : 2.7.1.40
Position : 6024349 - 6026118 bp
Length : 1770 bp
Strand : -
Note : PFAM: Pyruvate kinase, barrel domain; PEP-utilising enzyme, mobile domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; COGs: COG0469 Pyruvate kinase; InterPro IPR001697:IPR015793:IPR015795:IPR008279; KEGG: npu:Npun_F4277 pyruvate kinase;

DNA sequence :
ATGCAATTAAGAGATTCTATACGCCGGACAAAAATTGTCGCTACGATTGGTCCCGCAACTAGCAGCCCAGAAATGCTCAA
GGCGATCATTGAAGCGGGTGCAACTACGCTGCGGCTAAACTTTTCCCACGGAACCCATGCTGACCATCAGCGGAATATTC
GCTTAATTCGGCAAACTGCCTTTGAACTCAATCAGCCAGTGGCAATTCTCCAAGACTTGCAAGGGCCGAAAATTCGCTTG
GGTAAGTTTGAGAATGGGTCGATAATTGTTGCCAAAGGCGATCGCTTCACCTTGACAAATCGTCCAGTGATCGGCACACA
GGATATTAGCTGCATCACTTACGATTATTTAGCTGAAGAAGTCCCGGTTGGCGCTAAAATCCTCCTCGATGATGGGCGAG
TAGAAATGCTGGTCGAGGAGATTAACCGCGATAAAGGTGATTTACATTGTCGTGTTACGGTTCCTGGTAAACTTTCCAAC
AACAAAGGTGTAAACTTTCCTGGAGTTTATCTTTCAATTAAAGCTATGACCGACAAAGACCGAGAGGATCTCATGTTCGG
TCTAGATCAAGGTGTAGATTGGGTAGCACTTTCCTTTGTCCGCAACCCCCAGGATTTAATTGAAATCAAAGAACTAATTT
CTAGTACTGGTAAATATGTGCCAGTAGTTGCCAAAATTGAAAAGCATGAAGCCATTGAACAAATGGAAGCAGTTCTGGCT
TTGTGTGACGGCGTGATGGTAGCCAGAGGCGACTTAGGTGTGGAACTACCAGCCGAAGATGTCCCCATTCTGCAAAAGCG
GCTGATTGCTACAGCCAACCGCTTGGGGATTCCTATCATCACCGCCACCCAAATGTTAGACAGCATGGTGAGCAATCCCC
GTCCCACCCGTGCTGAAGTATCGGATGTGGCCAATGCGATTTTAGATGGCACGGATGCAGTCATGCTCTCTAATGAAACC
GCTGTTGGCGACTTTCCAGTAGAAGCTGTGGCGACAATGGCACGCATTGCGGAACGGATTGAGCAGGAAGAGGCGCTCAG
TTCTACAGTCCGTCAGTTAAGAGATGCTAGGCGTTCCATTCCCAACGCCATTAGTCAAGCTGTAGGTCAAATTGCAGAGC
AACTAGGTGCTGCGGCAATTATGACTTTGACGCAAACTGGAGCGACAGCCCGTAACGTTTCTAAGTTCCGTCCCCGGACA
CCTATTTTGGCAATTACACCCCATGTAAATGTGGCCAGACAGTTACAGATGGTGTGGGGAGTTAAACCGCTGTTAGTACT
GGGACTACCTTCGACTGGGCAAACTTTTCAAGCAGCGATTAATGTCGCTCAAGAAAATGAGCTACTAACTGAGGGAGATT
TGGTCGTAATGACTGCTGGTACACTCCAAGGGGTGTCTGGATCAACAGATTTAATTAAAGTTGAGGTAGTAACAGCAGTT
CTCGGCCAAGGAATTGGCTTGGGACAAGGTTCTGTGAGTGGTCGTGCTAGAGTTGCTCACACTGGTATGGAAGTTAGTAA
CTTTAATCCTGGCGATATTTTGGTTGCTCCCCGCACCAGCGCTGATTTTGTCGAGGCGATTCGCAAAGCTGCGGGGATTA
TTACAGAAGATGAAAGTCTCACAAGTCATGCAGCAGTGATTGGCTTGCGTCTAGGTGTACCTGTAATTGTTGGCGTGAAG
AAGGCGACGCAAGTAATTCGCGATGGGGCAATTCTGACGATGGACTTGCAACGGGGTTTAATTTACTCTGGAGCAGTCGG
AACACCTTAA

Protein sequence :
MQLRDSIRRTKIVATIGPATSSPEMLKAIIEAGATTLRLNFSHGTHADHQRNIRLIRQTAFELNQPVAILQDLQGPKIRL
GKFENGSIIVAKGDRFTLTNRPVIGTQDISCITYDYLAEEVPVGAKILLDDGRVEMLVEEINRDKGDLHCRVTVPGKLSN
NKGVNFPGVYLSIKAMTDKDREDLMFGLDQGVDWVALSFVRNPQDLIEIKELISSTGKYVPVVAKIEKHEAIEQMEAVLA
LCDGVMVARGDLGVELPAEDVPILQKRLIATANRLGIPIITATQMLDSMVSNPRPTRAEVSDVANAILDGTDAVMLSNET
AVGDFPVEAVATMARIAERIEQEEALSSTVRQLRDARRSIPNAISQAVGQIAEQLGAAAIMTLTQTGATARNVSKFRPRT
PILAITPHVNVARQLQMVWGVKPLLVLGLPSTGQTFQAAINVAQENELLTEGDLVVMTAGTLQGVSGSTDLIKVEVVTAV
LGQGIGLGQGSVSGRARVAHTGMEVSNFNPGDILVAPRTSADFVEAIRKAAGIITEDESLTSHAAVIGLRLGVPVIVGVK
KATQVIRDGAILTMDLQRGLIYSGAVGTP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 7e-83 43
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 6e-83 43
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 6e-83 43
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 9e-83 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Cal7507_5304 YP_007068476.1 pyruvate kinase VFG0479 Protein 2e-83 43