Gene Information

Name : Syn6312_0882 (Syn6312_0882)
Accession : YP_007060633.1
Strain : Synechococcus sp. PCC 6312
Genome accession: NC_019680
Putative virulence/resistance : Unknown
Product : HsdR family type I site-specific deoxyribonuclease
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 868743 - 871883 bp
Length : 3141 bp
Strand : -
Note : PFAM: Domain of unknown function (DUF3387); Type I restriction enzyme R protein N terminus (HSDR_N); Type III restriction enzyme, res subunit; TIGRFAM: type I site-specific deoxyribonuclease, HsdR family

DNA sequence :
ATGAGTTTTGTTACCGAAGACGACATTGAACAGGTACTCATCGAGCAACTGCAACACCTCGGTTATCATTACCTGCCCGA
TAGTGTTGCTAACCCCGATGGCACAGCCCCCGAGCGGGAATCCTATGCCGATGTCATTCTGCCTCAACGGTTGCGGGATG
CCCTAGATCGCCTAAACCCTACCATTCCCGCCACTGCCCGCGATGATGCCTTCAAAAAACTAATTGCCACCGAAAAGCCC
AACCTCATCGAAGAAAACCGCCGTCTGCATCAACTCCTCATCGAAGGCATTGATGTTGAGTTCTACAGTGACGATGGCAC
CATTCGCGGCGATAAAGTGTATGCCATTGACTTTGCCCAGCCTGAACAAAACGACTGGTTAGTGCTAAACCAATTTACCG
TCATCGAAGCAGGCCAGAACCGCCGCTCAGATGTCGTGGTCTTTGTGAATGGCTTGCCCCTGGCAGTGATTGAAATTAAA
AATCCTGGCACCGAAACCGCCACCCTCGCCGCCGCCTATAACCAACTGCAAACCTACAAAGCCCAAATTAGCTCCCTGTT
CAGAACCAACGCCGTTCTGGTCACAACCGATGGCCTCATGGCTCGCATTGGCTCCCTAACCGCAGACTTAGAACGGTTCA
TGCCCTGGCGTACCACGGATGGCGAAACCATTGCCCCCAAAGGCACACCGGAAATGTCCACCTTAGTCGAAGGGGTATTT
ACCAAACGCCACCTCCTGAACCTGATCCAAAATTTCACCGTCTTTGGCGACGATGGCACAGGCATTACCAAAATCATTGC
GGGCTATCACCAATTCCACGGTGTCCAGAAAGCCATCGCCAAAACCATAGCCGCTACCCATCAAACCGGAGATCGCAAAG
CGGGGGTCATCTGGCATACCCAAGGGTCAGGCAAAAGTTTACTGATGGCCTTCTATGTGGGGCAACTGGTTCGCCGTCCT
GAGCTAGAAAACCCCACCATTGTCGTGATTACAGATCGCAATGATCTAGACGATCAACTCTTTGCCACCTTTGCCATGTG
CCGGGATTTGATTCGCCAAACACCCCAACAGGCCAATAGCCGGGAAGACCTGCAAACCCTTCTTAATCAGGTATCCGGCG
GCGTCATCTTTACCACAATCCAAAAATTCGCTCCCCCCACTGGAGAAACCCGCTACCCCGTTTTAACCGAGCGGCGCAAC
GTCATCGTCATCGCAGATGAAGCCCACAGAAGCCAGTATGGATTTAAGGCCAAAGTGGATCAAAAAAGTGGGGTGATTGC
CTATGGCTTTGCCAAATATTTGCGGGATGCCCTACCCCATGCCTCCTTTATTGGCTTTACTGGAACCCCCATCGAAGCCA
GTGATGTGAATACGCCCGCTGTCTTTGGGAACTACATTGATATTTACGACATCAGCCGGGCTGTAGAAGATGGGGCAACC
GTGCCAATCTACTATGAAAGCCGTTTAGCCCGGATTGAGCTACCAGAGGATGAAAAACCGAAAATTGATGCCGAAATTGA
AGACCTGATTGATGATGAGGATTCAGACCAGGCCCGCCTCAGTCAAAAATGGGCCACCGTGCAAGCCCTCGTCGGAGCCG
AAAAACGGTTAAAACAAGTCGCCAGAGATTTAGTCACTCATTTTGAAAACCGAATCACCGCCCTGAAGGGTAAGGCCATG
ATCGTTTGCATGAGCCGGGCCATTTGCGTCAAACTCTACAACCATATTATTGAACTGCGACCCGATTGGCACTCAGACGA
TGAACAAGCCGGAATCATCAAAATTGTGATGACCGGGGCAGCGTCCGACCCTCCCGAGTGGCAACCCCACATTGGCAATA
AAGCTCGCCGGGATTTGATGGCTAAACGGCTGAAAGACCCCACCGACCCCTTGCAACTGGTGATTGTCAGGGATATGTGG
CTAACCGGCTTTGATGCCCCGGCCCTGCACACGATGTATGTGGATAAACCGATGAAAGGCCATGGTCTGATGCAAGCCAT
TGCCCGTGTGAACCGCGTCTTTCGGGATAAGCCTGCTGGCCTGGTGGTGGACTATATCGGCATTGGTCAACGGTTGCGGG
AAGCCCTCCGTGATTATTCAGCCCAAGACCAACGCCAGACCGGGATTGATGAAGCCGAAGCCGTGGCCCTGATGCTGGAA
AAATACGATGTTGTCCGGGCTATGTTTCATGGGTTTAATTACCAGCGGGGCCTGGATGGAACACCCCAAGAGCGATTGGT
GGTTATGGCTGAGGCGATGGAGTGGATATTAGACCAGCAACACCAAGCTGCCCTCCAAGAAACAGAACCAACCAAGCAAA
AACAGGCCCGCCGCCGTTATCAGGATGCAGTCTTAGCTCTCTCCAAAGCCTTTGCTTTAGCCGCCGCCAGTGATGAAGCT
CGGTCAATTCGGGATGAAGTGGGACTATTCCAAACCATTCGGGCAGCTTTAGTGAAATCTACAACCGGGCCTGGGCAGTC
AGCCGCCGAGCGAGAATTTGCTGTCCAACAAATTATTGATCGGGCTGTAGTCTCTACCGAAATTGTTGATATTCTCAGTG
CCGCTGGGCTTTCTTCTCCTGATATTTCTATTCTATCCGATGACTTTTTATTAGAAGTGCGGCAAATGGAGAAAAAAAAC
TTGGCGATTGAGGCCTTAAGACGATTACTCAATGATGAAGTTCGCTCCCGCAGTGCCAACAATATTACCCAGCAGAAAAA
GTTTTCAGAGCGGTTAGAACAAGCCATCGCCCGGTATCACACCAATGCCCTCAGTACCGTTGAAGTGATCCAAGAGTTAA
TTAATCTGGCCCAAGACATCAAAGCAGCCAAAGCACGAGGGGAAAACCAAGGGCTATCAGCGGATGAGTATGCCTTCTAT
GACGCTCTAGCCGAAAACCAAAGTGCAGTCGAAGTCATGGGAAATGAACAGTTAAAGATCATCGCCCATGAGTTGCTGGT
CAGTTTGAAGTCTAATGTCACGGTTGACTGGGCCCACCGTGAAAGTGCCAGGGCCAGGCTTCGGACAATCGTTAAACGTA
TCCTTAAAAAATATGGTTATCCCCCAGATATGCAAGCAATGGCCGTCCAAACTGTCCTCCAACAGGCCGAAGCGCTTTCT
GCCCATTGGGACAGAGCTTAA

Protein sequence :
MSFVTEDDIEQVLIEQLQHLGYHYLPDSVANPDGTAPERESYADVILPQRLRDALDRLNPTIPATARDDAFKKLIATEKP
NLIEENRRLHQLLIEGIDVEFYSDDGTIRGDKVYAIDFAQPEQNDWLVLNQFTVIEAGQNRRSDVVVFVNGLPLAVIEIK
NPGTETATLAAAYNQLQTYKAQISSLFRTNAVLVTTDGLMARIGSLTADLERFMPWRTTDGETIAPKGTPEMSTLVEGVF
TKRHLLNLIQNFTVFGDDGTGITKIIAGYHQFHGVQKAIAKTIAATHQTGDRKAGVIWHTQGSGKSLLMAFYVGQLVRRP
ELENPTIVVITDRNDLDDQLFATFAMCRDLIRQTPQQANSREDLQTLLNQVSGGVIFTTIQKFAPPTGETRYPVLTERRN
VIVIADEAHRSQYGFKAKVDQKSGVIAYGFAKYLRDALPHASFIGFTGTPIEASDVNTPAVFGNYIDIYDISRAVEDGAT
VPIYYESRLARIELPEDEKPKIDAEIEDLIDDEDSDQARLSQKWATVQALVGAEKRLKQVARDLVTHFENRITALKGKAM
IVCMSRAICVKLYNHIIELRPDWHSDDEQAGIIKIVMTGAASDPPEWQPHIGNKARRDLMAKRLKDPTDPLQLVIVRDMW
LTGFDAPALHTMYVDKPMKGHGLMQAIARVNRVFRDKPAGLVVDYIGIGQRLREALRDYSAQDQRQTGIDEAEAVALMLE
KYDVVRAMFHGFNYQRGLDGTPQERLVVMAEAMEWILDQQHQAALQETEPTKQKQARRRYQDAVLALSKAFALAAASDEA
RSIRDEVGLFQTIRAALVKSTTGPGQSAAEREFAVQQIIDRAVVSTEIVDILSAAGLSSPDISILSDDFLLEVRQMEKKN
LAIEALRRLLNDEVRSRSANNITQQKKFSERLEQAIARYHTNALSTVEVIQELINLAQDIKAAKARGENQGLSADEYAFY
DALAENQSAVEVMGNEQLKIIAHELLVSLKSNVTVDWAHRESARARLRTIVKRILKKYGYPPDMQAMAVQTVLQQAEALS
AHWDRA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hsdR YP_251977.1 type I restriction-modification system restriction subunit Not tested SCCmec Protein 0.0 49
hsdR BAD24840.1 type I restriction-modification system endonuclease homologue Not tested Type-V SCCmec Protein 0.0 49
hsdR BAH57699.1 type I restriction-modification system endonuclease homologue Not tested Type-VII SCCmec Protein 0.0 49
api52 CAF28526.1 hsdr-like Type I restriction enzyme Not tested YAPI Protein 0.0 48