Gene Information

Name : Syn6312_2113 (Syn6312_2113)
Accession : YP_007061777.1
Strain : Synechococcus sp. PCC 6312
Genome accession: NC_019680
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : -
COG ID : -
EC number : 2.7.1.40
Position : 2062605 - 2064386 bp
Length : 1782 bp
Strand : -
Note : PFAM: Pyruvate kinase, barrel domain; PEP-utilising enzyme, mobile domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase

DNA sequence :
ATGCCCAGTCGCTTCCTCAAACGTCGAACCAAAATTGTTGCCACCGTTGGCCCTGCCGTCAGTAGTCCAGAACTGTTAAG
GGCAATTATTGAAGCCGGAGCAACAACCCTACGCCTCAACTTTTCCCACGGCAGCCATGAGGATCATCAACGGAGTATTC
GTTTAATTCGCCAAATTTCCTATGAGCTAAACCAGCCCGTAGGTATCCTCCAAGACTTGCAGGGGCCGAAAATTCGTCTG
GGTAAATTTGAAAATGGCAAGATCAGTCTCCGGCCTGGGGATAAGTTTACCCTCACCAGTCGCATTCTCTTGGGTAATGA
AACCATCAGCACCATTACCTATCCTCCCCTCGCTAAAGAAGTGCCCCCCGGAGCAACAATCCTCCTTGATGATGGGCGGG
TGGAGATGGTTGTTGAGAATATAGACAAAATCAAAGAGGAACTCTATTGCCGAGTTGTGGTCGGGGGGCAGTTATCCAAT
GCCAAAGGGGTTAATTTCCCTGGTGTTTACCTATCCATTAAAGCCTTAACCGAAAAAGACCGGGCCGACCTCATGTTTGG
CTTAAACCAAGGGGTAGATTGGATTGCCCTCAGCTTTGTCCGCAATCCCCAGGATATGTTGGAAATTAAGGAACTGATCT
CAGCCGCTGGGAAATCTGTCCCTGTGATTGCCAAGATTGAAAAACACGAAGCCATTGAACAAATGGAGGCAGTGCTCTCG
GTCTGTGATGGGGTCATGGTGGCTCGGGGGGATTTGGGCGTAGAGCTCCCGGCGGAAGATGTCCCAATTTTGCAGAAACG
GCTGATTGCGGCGGCCAATCGGTTGGGCATTCCAGTCATTACTGCCACCCAAATGCTCGATAGTATGGTCAATTCCCCGC
GGCCAACAAGAGCAGAAATCTCTGATGTGGCCAACGCAATTTTGGACGGAACCGATGCGGTGATGCTGTCTAACGAAACG
GCAATGGGCCAATACCCCGTGGAGGCGGTGGCAACCATGGCCCGGATTGCCATGCGGATGGATGACCAGGCCCAACTGCA
TCGGTCTCCCCCTGCCTCAGTCCCCGGCCAATCCATTCCCAACGCTATCAGTCAGGCCGTGGGTCAGGTGGCGGCCCAAC
TCAATGCCAAAGCGATTATTACCCAAACAAAAACTGGGGCCACAGCTCGGAATGTGTCTAAGTTTCGGCCCCAGATTCCA
ATTTTGGCCGCAACGCCCCAACTCGATATTGCCCGGCGACTGCAATTGGTGTGGGGTGTGGAGCCTTTACTCACCCTCAA
TCAAGGCTCAATTCGGCAATCCTTCCAAGTTGCAATTAATACTGCCCAAGAGCGGGGCCTGCTTGCTGAACGGGATTTGG
TCGTAATGACAGCCGGAACATTACAGGGAGTTTCTGGCTCAACGGACATGATTAAGGTGGAAATTGTCACCTCGATTATG
GGGCGGGGGGCGGGAATTGGGCATGGTTCTGTGAGTGGGCCAGCCCGAGTGATTCCGGAGGGGGCGCGGATTAGCTCTTT
TAATCCGGGAGAGATTTTGGTCACATCCCGGACTAACGCCGACTATGTGGACGTGATTCGCAAAGCTGCTGGAATTATTA
CTGAAGAAGAAAGTCTGACCAGTCACGCCGCGGTGTTGGGCCTACGCTTGGGTATTCCCGTTATTGTTGGGGTTAAAAAT
GCTACAGATATTATTCGAGAAGGGACAATTTTGACGTTGGATGTACAGCGGGGCCTGGTCTATTCAGGTTCTGTCAATAG
CCTTAAGGAGCACTATTCCTAG

Protein sequence :
MPSRFLKRRTKIVATVGPAVSSPELLRAIIEAGATTLRLNFSHGSHEDHQRSIRLIRQISYELNQPVGILQDLQGPKIRL
GKFENGKISLRPGDKFTLTSRILLGNETISTITYPPLAKEVPPGATILLDDGRVEMVVENIDKIKEELYCRVVVGGQLSN
AKGVNFPGVYLSIKALTEKDRADLMFGLNQGVDWIALSFVRNPQDMLEIKELISAAGKSVPVIAKIEKHEAIEQMEAVLS
VCDGVMVARGDLGVELPAEDVPILQKRLIAAANRLGIPVITATQMLDSMVNSPRPTRAEISDVANAILDGTDAVMLSNET
AMGQYPVEAVATMARIAMRMDDQAQLHRSPPASVPGQSIPNAISQAVGQVAAQLNAKAIITQTKTGATARNVSKFRPQIP
ILAATPQLDIARRLQLVWGVEPLLTLNQGSIRQSFQVAINTAQERGLLAERDLVVMTAGTLQGVSGSTDMIKVEIVTSIM
GRGAGIGHGSVSGPARVIPEGARISSFNPGEILVTSRTNADYVDVIRKAAGIITEEESLTSHAAVLGLRLGIPVIVGVKN
ATDIIREGTILTLDVQRGLVYSGSVNSLKEHYS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 3e-83 42
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 8e-83 42
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 4e-83 42
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 3e-83 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Syn6312_2113 YP_007061777.1 pyruvate kinase VFG0479 Protein 1e-83 42