Gene Information

Name : Cyagr_3375 (Cyagr_3375)
Accession : YP_007047783.1
Strain : Cyanobium gracile PCC 6307
Genome accession: NC_019675
Putative virulence/resistance : Resistance
Product : copper/silver-translocating P-type ATPase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 3277060 - 3279162 bp
Length : 2103 bp
Strand : -
Note : PFAM: E1-E2 ATPase; haloacid dehalogenase-like hydrolase; TIGRFAM: copper-(or silver)-translocating P-type ATPase; heavy metal translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; heavy metal-(Cd/Co/Hg/Pb/Zn)-transloc

DNA sequence :
ATGGATTGCGCCACGGAGGAAGGCGAGATCCGCCATGCCCTCGCAGGTGTCGACGGCATCCGTGGCCTGAGGTTCCTGCT
GGCCGAGCGCGTTCTGGCGATCGATGCCGAAGCGGCCGCGCTAAGCTCCGCCCTTGCTGCGATTCGCCGGCTGGGGTTCA
ACCCGGAGACGATCAGCCCCGATCACCGGCCGTCCGCCGCCCAGACCCGGGCCGAACGGCTCCGTGAACGGCTTCGCCTG
GCGGGCTCCCTGGCGTTGGCGGTCACGGCGGAGCTGCTGCATCTGGTCGTTCCCCCCTTCCCTGGCCACGAGCTGCTGGA
GATCGGAATCGCCATCGCCGCGATCGCCCTGGCGGGCTTCTCCGTGTTTCGCAAGGGCCTGGCCGCGTTGCGCCAGGGCC
GTCTCAACATCAATGCGCTGATGAGCGTGGCGGTCACGGGCTCCTTCCTGATCGGCCGCTTCCCGGAAGCCGCCATGGTG
ATGGCGCTCTATGCCGTGGCCGAGGCGATTGAGGCGCGGGCGGTGGAGCGGGCCCGCCAGGCGATCACCAGCCTGATGGC
CCTGGCCCCTGACGAGGCGGAGATCCGTCAGAGCGATGGCCGCTGGCAGCGCGTGTCCGCCAGCGCTGTGGCCATCGGCG
ATGTGGCGCGTGTCCGCCCGGGCGAGCGGCTGCCGCTCGATGGCACGGTGCTTTCTGGCGTGAGCGCGATCGATCAGGCC
CCGATCACCGGCGAAAGCCTGCCGGTGGACAAAGGCCCGGGGGACGCGGTGTTCGCCGGCACGATCAACCAGGGCGGCGC
CCTGGAAATCCAGGTGACGGCGCCCGCCTCACTCAGCACCCTGGCGCGGATCATCCAGGCCGTGGAGGAGGCCCAGGCTT
CCCGCGCCCCGATCCAGCGCTTCGTCGATCGCTTCGCGGCCCATTACACCCCGGCGGTGTTCGTGGTCGCCCTGGCCGTT
GCCCTGCTGGCGCCACCTCTTCTGGGATTCACTCCGCCCCAGGCGATCTACAAGGCCCTGGTGCTGCTGGTGATCGCCTG
CCCCTGCGCCCTGGTGATCGCCACCCCGGTCACGGTGGTGAGCGGCCTGGCCACCGCCGCCCGTCGCGGCATCATCATCA
AGGGCGGCCTCTACATCGAAGAGGCCCGCAAGATCAAGGTTCTGGCGCTCGACAAGACCGGCACGATCACCCTGGGCAAG
CCCAAGCTGGTGGCGTTCTCTCCACAGCAAGAAGGCTCAGACGCTGACGCGCTCAAGCAGTGGGCCAGCAGCTTGGCGGG
GCGCTCCGACCATCCGGTCTCGCAGGCGGTGGCCACAGGCCTTGATGGCGAGCGGCTGGCCGTGGAGGCCTTCGAGGCCC
TGCCGGGGCGCGGTGTGCGCGGCGTGATCGCGGGACGGCGGCTGATGCTGGCCAACCACCGCTGGATCGATGAGCTGGGG
CTCTGCTCCAGCACACTGGAGGCGTCGATGCAGGTCCATGAGCGCCAGGGCCGCTCCCTGAGCCTGCTCGCGGATGTCAG
CGGCGTGCTCGCCCTGATCGCCGTCGCCGACACCGTGCGGCCCAGCTCCGCGGCCGCCATGGAGGCTCTGCGGGCCCTCG
GCGTCACCCCGGTGATGCTCACGGGCGACAACGCAGCCACCGCCGAAGCAATTGCGGCCATAGCTGGCATCGAGCAGGTG
AAGAGCAACATGCTGCCCCAGGACAAGCTCGAGGCGGTGGCCGATCTGCAGGCCCGCTATGGATTCACGGCCATGGCCGG
CGATGGCATCAACGATGCACCGGCCCTGGCCCAGGCGGACATCGGCTTTGCGATGGGGGCCGCGGGCACCCATATCGCCA
TCGAAGCCGCCGACGTGGTGATCATGAATGACGATCTGATGCGCGTTCCGGAAACGATCGCTCTCTCTCGCCGCACCTTT
CGAATCCTGCGCCAGAACATCGCGCTGGCGCTGGGAATCAAGGCCCTCTTTCTGGTACTCACCGTGGCCGGAAATGCCAC
GATGTGGATGGCGGTCTTCGCGGACATGGGCACCAGCCTGATCGTGATCGCCAATGGCCTTCGTCTGATCCGCATGCCCA
ATGTCCTTGCTCTTCGCGGCTAA

Protein sequence :
MDCATEEGEIRHALAGVDGIRGLRFLLAERVLAIDAEAAALSSALAAIRRLGFNPETISPDHRPSAAQTRAERLRERLRL
AGSLALAVTAELLHLVVPPFPGHELLEIGIAIAAIALAGFSVFRKGLAALRQGRLNINALMSVAVTGSFLIGRFPEAAMV
MALYAVAEAIEARAVERARQAITSLMALAPDEAEIRQSDGRWQRVSASAVAIGDVARVRPGERLPLDGTVLSGVSAIDQA
PITGESLPVDKGPGDAVFAGTINQGGALEIQVTAPASLSTLARIIQAVEEAQASRAPIQRFVDRFAAHYTPAVFVVALAV
ALLAPPLLGFTPPQAIYKALVLLVIACPCALVIATPVTVVSGLATAARRGIIIKGGLYIEEARKIKVLALDKTGTITLGK
PKLVAFSPQQEGSDADALKQWASSLAGRSDHPVSQAVATGLDGERLAVEAFEALPGRGVRGVIAGRRLMLANHRWIDELG
LCSSTLEASMQVHERQGRSLSLLADVSGVLALIAVADTVRPSSAAAMEALRALGVTPVMLTGDNAATAEAIAAIAGIEQV
KSNMLPQDKLEAVADLQARYGFTAMAGDGINDAPALAQADIGFAMGAAGTHIAIEAADVVIMNDDLMRVPETIALSRRTF
RILRQNIALALGIKALFLVLTVAGNATMWMAVFADMGTSLIVIANGLRLIRMPNVLALRG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 1e-89 42
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 1e-89 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Cyagr_3375 YP_007047783.1 copper/silver-translocating P-type ATPase BAC0298 Protein 6e-132 61
Cyagr_3375 YP_007047783.1 copper/silver-translocating P-type ATPase BAC0092 Protein 9e-70 41
Cyagr_3375 YP_007047783.1 copper/silver-translocating P-type ATPase BAC0461 Protein 6e-70 41