Gene Information

Name : metB (BN6_07770)
Accession : YP_007034979.1
Strain : Saccharothrix espanaensis DSM 44229
Genome accession: NC_019673
Putative virulence/resistance : Resistance
Product : Cystathionine gamma-synthase
Function : -
COG functional category : -
COG ID : -
EC number : 2.5.1.48
Position : 786956 - 788113 bp
Length : 1158 bp
Strand : +
Note : -

DNA sequence :
ATGACGGACACCGGCCACTACGGTTTCGCGACCAGGGCCATCCACGCCGGACAGGACCCGGACCCCACGACGGGCTCGGT
CATCGTGCCCATCCACGCCACCTCGACCTACGCCCAGGACGGCGTCGGCGGGCTGCGCGGCGGCTTCGAGTACTCGCGCA
CCGGCAACCCCACCCGGACCGCGCTGGAGGAGTGCCTGGCGGCCCTCGAAGGCGGCCGGCACGCCCGCGCGTTCGCCTCG
GGCATGGGCGCGACCGACGCCGCCCTGCGCGCCCTGTGCCGTCCCGGCGACCACGTGGTGATCCCGAACGACGCGTACGG
CGGCACGTTCCGCCTGATCGACAAGGTGTTCGGCCTCTGGGGCGTGGAGCACACGCCGGTCGCGCTGTCCGACGTGGACG
CGGTGCGCGCGGCGATCCGCCCGAACACCAAGGTCGTCTGGATCGAGACCCCGACCAACCCGCTGTTGAACATCGCCGAC
ATCGCCCTGCTCGCCCAGGTCGCGCACTCCGCCGGCGCGCGGCTCGTGGTGGACAACACCTTCGCCTCGCCGTACCTGCA
GAGCCCGCTCGCGCTCGGCGCGGACGTGGTGCTGCACTCGACCACCAAGTACGTGGGCGGCCACTCCGACGTCATCGGCG
GCGCGCTGGTCACCTCGGACGACGAGCTGGACGCGGCGTTCGGCTTCCTGCAGAACGGCGCGGGCGCGGTGCCCGGCCCG
TTCGACGCGTGGCTGACCCTGCGCGGCATCAAGACCCTCGAACTGCGCATGGAGAAGCACTCGGACAACGCCGAGCTGGT
CGCCGAGGCGCTCCAGCGGCACCCGCGGGTGCAGTCGGTGATCTACCCCGGCCTGCCCGAGCACCCCGGCCACGAGGTCG
CGGCCAAGCAGATGCGCCGGTTCGGCGGGATGGTCTCGTTCACCGTGGCGGGCGGCGAGGAAGCGGCCCTGCGGGTCTGC
TCGCGCACCCGGCTGTTCACGCTGGCCGAGTCGTTGGGCGGCGTCGAGTCGCTGATCGAGCACCCCGGGAAGATGACCCA
CGCCAGCACGGCCGGTTCGCTGCTGGAGGTGCCGGCCGACCTGATCCGGATCTCGGTCGGGATCGAGTCCGGGGACGACC
TGGTGGCGGATCTGGTGCAGGCCCTCGACTCGGTCTGA

Protein sequence :
MTDTGHYGFATRAIHAGQDPDPTTGSVIVPIHATSTYAQDGVGGLRGGFEYSRTGNPTRTALEECLAALEGGRHARAFAS
GMGATDAALRALCRPGDHVVIPNDAYGGTFRLIDKVFGLWGVEHTPVALSDVDAVRAAIRPNTKVVWIETPTNPLLNIAD
IALLAQVAHSAGARLVVDNTFASPYLQSPLALGADVVLHSTTKYVGGHSDVIGGALVTSDDELDAAFGFLQNGAGAVPGP
FDAWLTLRGIKTLELRMEKHSDNAELVAEALQRHPRVQSVIYPGLPEHPGHEVAAKQMRRFGGMVSFTVAGGEEAALRVC
SRTRLFTLAESLGGVESLIEHPGKMTHASTAGSLLEVPADLIRISVGIESGDDLVADLVQALDSV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 3e-74 48
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 3e-75 48
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 3e-57 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
metB YP_007034979.1 Cystathionine gamma-synthase BAC0207 Protein 5e-63 44