Gene Information

Name : vanH (BN6_49770)
Accession : YP_007039119.1
Strain : Saccharothrix espanaensis DSM 44229
Genome accession: NC_019673
Putative virulence/resistance : Resistance
Product : D-specific alpha-keto acid dehydrogenase
Function : -
COG functional category : -
COG ID : -
EC number : 1.1.1.-
Position : 5558259 - 5559311 bp
Length : 1053 bp
Strand : -
Note : -

DNA sequence :
TTGACTGGAGGCATGTCCAACAGCGAACCGGCGCGAACCGCGGCTCGCCGCTCCCGATCGCCGATGGTCCGGCGGCCCTC
CGTCGCCCCGGTGCTGGGCGTGACGATCTACGGGTGCGACGCGGACGAGGCCGTTGCCTTCCGGGAGACGGCGTCGCGCT
TCGGCGTCGCGCTGACCATCACCGAGGCGGCGGTGTCCGAGACCAACGTCGAACTGGCGTCGGGCAACCGGTGCGTCAGC
GTCGGCCACAAGGTCCGGATCGAGAACGCCGCTCTTCTCGCGCTCAGCCGGGCCGGTGTGCGGTACGTGTCCACGAGGAG
CATCGGGTACAACCACATCGACGTCGAGTACGCGGAAAGCCTCGGCCTGGTGGTCGAGAACGTCTCCTACTCGCCCGACA
GCGTCGCCGACTTCACGCTGATGCTGATGTTGATGGTCGTGCGCAACGCGAAATCCCTCCTCCGCAGCACCGATGCCCAC
GACTACCGGCTGGGGGACGTGCGGGGGAGGGAACTGCGCGACCTGACCGTCGGGGTCATCGGTACGGGCCGGATCGGCAC
GGCGGTCGTGGCCAGGCTGCGCGGGTTCGGCTGTCGCGTGCTGGCCTACGACAAACGTCCCGGTATCGGCGTCGACCACG
TCTCGCTCGACGAACTGCTGCGGTCGAGCGACATCGTCACGCTGCACGCCCCGCTCAACGCGGAGACGCACCACCTGGTG
AACGGGCCGCGCATCGCGCAGTTGAAGGACGGTGCGTTCATCGTCAACACCGGGCGCGGCCCACTTCTCGACACCGATGC
CCTCCTCGCGGCGTTGGAGACCGGCCGATTGGGCGGTGCGGCGCTGGACGTGCTCGAAGGGGAGGAAGGGATCTTCTACG
CCGACTGCCGCAACCGGGACGTCAGCGAGGCGCTGGTGCGGCTGCAACGCCTGCCGAACGTCCTGATCAGTCCGCACACC
GCCTACTACACGGACCACGCGCTGCGGGACACCGTGCAGAACAGCCTCATCAACTGCTTGAACTTCGACAGCGAAAGGCG
ACACTGGGTATGA

Protein sequence :
MTGGMSNSEPARTAARRSRSPMVRRPSVAPVLGVTIYGCDADEAVAFRETASRFGVALTITEAAVSETNVELASGNRCVS
VGHKVRIENAALLALSRAGVRYVSTRSIGYNHIDVEYAESLGLVVENVSYSPDSVADFTLMLMLMVVRNAKSLLRSTDAH
DYRLGDVRGRELRDLTVGVIGTGRIGTAVVARLRGFGCRVLAYDKRPGIGVDHVSLDELLRSSDIVTLHAPLNAETHHLV
NGPRIAQLKDGAFIVNTGRGPLLDTDALLAALETGRLGGAALDVLEGEEGIFYADCRNRDVSEALVRLQRLPNVLISPHT
AYYTDHALRDTVQNSLINCLNFDSERRHWV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
EF2295 NP_815952.1 D-specific alpha-keto acid dehydrogenase Not tested Not named Protein 3e-80 56
vanHB YP_008394258.1 VanH protein, D-specific alpha-keto acid dehydrogenase Not tested Not named Protein 1e-78 55

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
vanH YP_007039119.1 D-specific alpha-keto acid dehydrogenase NC_005054.2598279.p0 Protein 7e-86 59
vanH YP_007039119.1 D-specific alpha-keto acid dehydrogenase NC_014475.1.orf2.gen Protein 7e-86 59
vanH YP_007039119.1 D-specific alpha-keto acid dehydrogenase AF155139.2.orf4.gene Protein 7e-83 59
vanH YP_007039119.1 D-specific alpha-keto acid dehydrogenase FJ349556.1.orf3.gene Protein 2e-81 57
vanH YP_007039119.1 D-specific alpha-keto acid dehydrogenase U35369.1.gene5.p01 Protein 2e-80 56
vanH YP_007039119.1 D-specific alpha-keto acid dehydrogenase AF310956.2.orf4.gene Protein 3e-79 55
vanH YP_007039119.1 D-specific alpha-keto acid dehydrogenase AF130997.1.orf3.gene Protein 3e-73 54