Gene Information

Name : BN6_49760 (BN6_49760)
Accession : YP_007039118.1
Strain : Saccharothrix espanaensis DSM 44229
Genome accession: NC_019673
Putative virulence/resistance : Resistance
Product : putative D-alanine-D-lactate ligase
Function : -
COG functional category : -
COG ID : -
EC number : 6.3.2.-
Position : 5557231 - 5558262 bp
Length : 1032 bp
Strand : -
Note : -

DNA sequence :
ATGAAGATCGGAATCATCTTCGGGGGTACTTCCGAAGAACATCCCGTGTCCGTGAAGTCCGCCCAGGAGGTCGCGAAGAG
CCTCGACCCGGAGAAGTACGAGCCGTACTGGATCGGGATCGCGGAGAACGGCTCCTGGTGGCTCTGCGACGGCCCGGACG
TCGACGGGGAGGGCGGCGGGCGCCGTCCGGTCGTGCTCTCCACGGACAGCGGCGTGCACGGCCTGCTCGTCCTGGAGGAC
GGCAAGTACGAGGAGGTCGGGCTGGACGTCGTGCTGCCCGTGCTGCACGGCAGGTTCGGCGAGGACGGGGCCGTGCAGGG
CCTGTTGGAGTTCTCCGGCATCCCCTACGTCGGCTGCGACGTCCAGAGCTCCGCCCTGTGCATGGACAAGGCGCTCGCCT
ACACCGTCGTCCGGGCCGCGGGGATCCCCACGCCGGACTTCCTGGTCGTCCCGGCGGGCGAGGACGTCGAGCCCGGCGGG
CTGACCTACCCGGTCTTCGTGAAGCCGGCCCGGTCGGGGTCGTCGTTCGGCGTCACCAAGGTCTCCCGCCCCGAGGAACT
GCGCAGCGCCGTGGAGACCGCGCGGCGGTACGACTCGAAGGTGTTGGTCGAAGAGGGGATCGTCGCCGCCGAGATCGGCT
GCGCGATCCTGGGCGACGACGTGGACCTGGTCATCGGCGAACCCGACCAGATCACGCTGTCCCACGGGATCTTCCGGATC
CACCAGGAGGAGAACCCGGAGGGCGGGTCGGAGAACTCGACCATCACCGTTCCCGCCGACATCCCGGCGGAGTCGCGCGC
GCTGGTCCAGGAGACCGGCAAGGCCGTCTACCGCGCTCTGGGGTGCCGGGGGCTGGCGCGCGTCGACCTGTTCCTGACCG
ACGACGGCGAGGTGATCCTCAACGAGGTCAACACCTTGCCCGGCCTCACGTCGTACAGCCGCTACCCGCGCATGATGGCC
GCCGCCGGGCTGTCGCCGGCGGACGTGCTCGACCGGCTCGTGTCGCTGGCGGTGGCCGGGAACGTCCGGTGA

Protein sequence :
MKIGIIFGGTSEEHPVSVKSAQEVAKSLDPEKYEPYWIGIAENGSWWLCDGPDVDGEGGGRRPVVLSTDSGVHGLLVLED
GKYEEVGLDVVLPVLHGRFGEDGAVQGLLEFSGIPYVGCDVQSSALCMDKALAYTVVRAAGIPTPDFLVVPAGEDVEPGG
LTYPVFVKPARSGSSFGVTKVSRPEELRSAVETARRYDSKVLVEEGIVAAEIGCAILGDDVDLVIGEPDQITLSHGIFRI
HQEENPEGGSENSTITVPADIPAESRALVQETGKAVYRALGCRGLARVDLFLTDDGEVILNEVNTLPGLTSYSRYPRMMA
AAGLSPADVLDRLVSLAVAGNVR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
vanB YP_008394259.1 Vancomycin B-type resistance protein vanB, D-alanine--D-lactate ligase Not tested Not named Protein 7e-104 62
vanB NP_815951.1 D-alanine--D-lactate ligase Not tested Not named Protein 3e-101 61

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
BN6_49760 YP_007039118.1 putative D-alanine-D-lactate ligase AY145441.gene.p01 Protein 4e-103 62
BN6_49760 YP_007039118.1 putative D-alanine-D-lactate ligase AF310956.2.orf5.gene Protein 5e-103 62
BN6_49760 YP_007039118.1 putative D-alanine-D-lactate ligase U00456.gene.p01 Protein 1e-101 61
BN6_49760 YP_007039118.1 putative D-alanine-D-lactate ligase U35369.1.gene6.p01 Protein 1e-101 61
BN6_49760 YP_007039118.1 putative D-alanine-D-lactate ligase AE016830.1.gene2250. Protein 1e-101 61
BN6_49760 YP_007039118.1 putative D-alanine-D-lactate ligase AF277571.gene.p01 Protein 6e-106 61
BN6_49760 YP_007039118.1 putative D-alanine-D-lactate ligase AY489045.gene.p01 Protein 2e-102 60
BN6_49760 YP_007039118.1 putative D-alanine-D-lactate ligase AF130997.1.orf4.gene Protein 1e-104 59
BN6_49760 YP_007039118.1 putative D-alanine-D-lactate ligase NC_005054.2598280.p0 Protein 1e-98 58
BN6_49760 YP_007039118.1 putative D-alanine-D-lactate ligase NC_014475.1.orf3.gen Protein 1e-98 58