Gene Information

Name : entE (BN6_27010)
Accession : YP_007036886.1
Strain : Saccharothrix espanaensis DSM 44229
Genome accession: NC_019673
Putative virulence/resistance : Virulence
Product : 2,3-dihydroxybenzoate-AMP ligase
Function : -
COG functional category : -
COG ID : -
EC number : 2.7.7.58
Position : 2863452 - 2865059 bp
Length : 1608 bp
Strand : +
Note : -

DNA sequence : 
GTGAACGACTGGACACCGTGGCCCGAGGAGTTCGCCCGCCGCTACCGCGAGGCCGGCTACTGGACCGGTGAGACCTTCGG
CGACTTCCTCGCCGCGCGGGCCGAGGCGTTCGCCGACCGGATCGCCGTGGTCGACGGCGACCGGCGGTGGACCTACCGTG
AGCTGGACGAGCGCGCCTCGGCCATGGCGCACGGGTTCCTGGCGCGCGGGATCGAGCCGGGCGACCGGGTCGTGGTGCAG
CTGCCGAACGTCGCCGAGTACACCTCCGTGGTGTTCGGGCTGTTCCGCGCCGGCGCGCTGCCGGTGTTCGCGCTGCCGCC
GCACCGGTCTGCCGAGATCTCGGCGTTCTGCGAGATCACCGGCGCGGTGGCGTACGTGATCGCCGATTCCTCCGGCGGCT
TCGACTTCCGGGCGCTGGCGTCGGAGGTGAAGGAGGCGACGGCGCTGGAGCACGTGTTCGTGCTCGGCGACCCGGGCGAG
CACACCGCGCTGGCCGACGTGCCGGCGGCGGGCGGCGACCTGCCCGAGGTGCGCTCCGGCGACGTGGCGTTCCTCCAGCT
GTCCGGCGGCAGCACCGGTATCCCGAAGCTCATCCCGCGCACCCACGACGACTACCTCTACAGCGTGCGGGAGAGCGCGG
TGATCTGCGAACTGGGGGAGGACACCGTCTACCTGGTCGCGCTGCCGGTCGCGCACAACTTCCCGATGTCCTCGCCCGGC
ATCCTCGGCGTCCTGCACGCCGGCGGCCGGATCGTGCTGGCGCCCGCGCCGAGCCCGGACGTGGTCTTCCCGCTGATCGC
CCGGGAAGGCGTGACGTCGACGGGCGTCGTGCCGCCGATCGCGTTGCAGTGGATGAACTCCCCGGCCCGCGCCGAGCACG
ACCTGTCCAGCCTGCGGGTGATCCAGGTCGGCGGCGCGAAGTTCGTGCCGGAGGCCGCGCGCCGGGTCCGCGCCGAGCTG
GGCTGCGCGTTGCAGCAGGTGTTCGGCATGGCCGAGGGCCTGGTGAACTACACGCGGTTCGACGACCCGGACGAGGTCGT
GGTGACCAGCCAGGGCCGGCCGATCTCGCCGGACGACGAGATCCGGATCGTCGACGGCGACGGCGCGGAGGTCCCGCCCG
GCGAGGTCGGCGAGCTGCTGACCCGCGGCCCGTACACGATCCGCGGCTACTACCGGGCCGACGCGCACAACCTGGTCGCC
TTCACCCCGGACGGCTTCTACCGCACCGGCGACCTGGTGCGCCGCCTGCCGACCGGCCACCTGGTGGTCGAGGGCCGGGC
CAAGGACCAGATCAACCGGGGCGGCGAGAAGATCGCCGCCGAGGAGATCGAGAACCACCTGCTCGCCCACCCCGCCGTGC
ACGACGCCGCGGTGGTCGGCATCCCGGACGACTACCTGGGCGAGCGGACGTGCGCGTTCGTCATCGCGACCGGCGAACCG
CCGACCGGCCCGGCGCTGCGCGCGTTTCTGCGCGGCCGGGGCCTGGCCGCCTACAAGATCCCGGACCGCATCCAGCTCGT
GGACGCGTTCCCGCACACCGGGGTCGGCAAGACCAGCCGTCGCGACCTGCGGCGGGCGCTGGCCGACACGTTCAGAAAGG
CGCAGTGA

Protein sequence : 
MNDWTPWPEEFARRYREAGYWTGETFGDFLAARAEAFADRIAVVDGDRRWTYRELDERASAMAHGFLARGIEPGDRVVVQ
LPNVAEYTSVVFGLFRAGALPVFALPPHRSAEISAFCEITGAVAYVIADSSGGFDFRALASEVKEATALEHVFVLGDPGE
HTALADVPAAGGDLPEVRSGDVAFLQLSGGSTGIPKLIPRTHDDYLYSVRESAVICELGEDTVYLVALPVAHNFPMSSPG
ILGVLHAGGRIVLAPAPSPDVVFPLIAREGVTSTGVVPPIALQWMNSPARAEHDLSSLRVIQVGGAKFVPEAARRVRAEL
GCALQQVFGMAEGLVNYTRFDDPDEVVVTSQGRPISPDDEIRIVDGDGAEVPPGEVGELLTRGPYTIRGYYRADAHNLVA
FTPDGFYRTGDLVRRLPTGHLVVEGRAKDQINRGGEKIAAEEIENHLLAHPAVHDAAVVGIPDDYLGERTCAFVIATGEP
PTGPALRAFLRGRGLAAYKIPDRIQLVDAFPHTGVGKTSRRDLRRALADTFRKAQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 7e-110 49
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 9e-109 49
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 9e-109 49
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 9e-109 49
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 9e-109 49
ybtE CAA21394.1 - Virulence HPI Protein 9e-109 49
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 9e-109 49
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 9e-110 49
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 7e-109 49

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
entE YP_007036886.1 2,3-dihydroxybenzoate-AMP ligase VFG0168 Protein 3e-132 53
entE YP_007036886.1 2,3-dihydroxybenzoate-AMP ligase VFG1817 Protein 1e-115 49
entE YP_007036886.1 2,3-dihydroxybenzoate-AMP ligase VFG0932 Protein 6e-115 48