Gene Information

Name : cadA1 (PputUW4_05166)
Accession : YP_007032161.1
Strain : Pseudomonas sp. UW4
Genome accession: NC_019670
Putative virulence/resistance : Resistance
Product : cadmium-translocating P-type ATPase
Function : -
COG functional category : -
COG ID : -
EC number : 3.6.3.3
Position : 5889144 - 5891405 bp
Length : 2262 bp
Strand : -
Note : [P] COG2217 Cation transport ATPase

DNA sequence :
ATGAGCGATTCTCAGCATACCCACAAACCTGTGGCCGAACATGAAATCGGCGTTAAGCTTCGACCCTTACCCAAGCATGA
CCATGGCGGTCATGGCGACGCTTGCTGTTCATCAAAAACGGCAGCGCCTGCGCGGGTCACGCTGAGCGCATCGCCGACGG
CGGGTGCCCGTCTGAGCAGCTTTCGCATCGAGGCGATGGACTGCCCGACCGAGCAGACGCTGATCCAGAACAAGCTAAGC
AAACTGACAGGCGTGCAGCAGCTGGAGTTCAATCTGATCAACCGGGTGCTCGGCGTGACCCACGATTTGCCAGGCACCGA
GCCAATCACCGAGGCGATCAAGTCCCTGGGCATGCACGCCGAACCGCTGGAGCAGGGGGCTGAAACACCGGCAGCGAAAC
CCGACAGGAAACACTGGTGGCCATTGGCGTTGTCCGGTGTGGGCGCATTGCTGGCGGAAGTCATCCACTTCACCGCGACC
GCGCCTGATTGGATGGTAGCGGTAATTGCGCTGGTGTCCATCCTCAGCGGCGGTCTCGGCACCTATAAAAAGGGCTGGAT
CGCGCTCAAGAACCTCAATCTGAACATCAACGCACTGATGAGCATTGCCGTCACCGGCGCCGTCCTGATCGGTCAGTGGC
CGGAAGCGGCGATGGTGATGTTCCTGTTCACCGTGGCCGAGCTGATCGAGGCTCGCTCCCTGGATCGTGCGCGCAATGCC
ATCGGCGGGCTGATGCAGATGGCGCCGGAGCAGGCGACGGTGTTGCAGGCCGACGGCAGTTGGGTCGAGCAGGATGTCAA
AATCATCGAAATCGGCGCGCGGGTGCGTGTGCGTCCCGGCGAACGTATTGGTCTGGACGGCGAGGTCCTGTCCGGGCGTT
CGACCATCGATCAGGCGCCCATTACCGGGGAAAGCCTGCCGGTAGAGAAAACCGTCGGCGACAAAGTGTTCGCCGGTACC
ATCAATCAGGCCGGTTCCCTTGAGTACGCGGTCACTGCCGTCGCGGGCAATTCGACTCTGGCACGCATCATTCACGCCGT
TGAACAGGCGCAAGGCGCGCGGGCGCCGACCCAGCGATTCGTCGATCAATTTTCGAAAATCTACACCCCGGTAGTGTTTG
TTCTTGCGCTGGCCGTGGCGGTCATCCCACCGCTGTTCATGGGCGCGTTGTGGTTCGACTGGATTTACCGGGCGCTGGTG
CTGTTGGTGGTGGCGTGCCCGTGCGCACTGGTGATTTCCACGCCGGTGACCATCGTCAGCGGCCTCGCAGCGGCGGCGCG
CAAAGGGATCCTGGTCAAGGGCGGCGTCTATCTGGAGGGTGGTTACAAGCTCGACTACCTGGCCCTGGACAAGACCGGCA
CCATCACCCACGGCAAGCCGGTGCAGACCGATTACCTGTCGCTGGACCCGACCGCCGATGCTTCGGCGCCAACCATTGCC
GCCGCGCTGGCCGGGCGTTCGGATCATCCGGTTTCCCTGGCCATCGCCAAAGCGGCTGTGGATAACCAAAGCGCGACGCT
GATTGTGGATAACTTCGAAGCCCTGGGCGGGCGCGGTGTGCGCGGCGAGATCAACGGCCAGCTCTACCATTTGGGTAACC
ATCGTCTGGTGGAGGATCTGGGCCTGTGCTCTCCGGCGCTGGAAGAAAAACTGTTTGCTCTGGAAAAGCAGGGCAAGTCG
GTGGTGCTGCTGCTTGATTCGTCCGGTCCTTTGGCACTGTTCGCTGTCGCCGATACGGTAAAGGCCTCCAGTCGCGAAGC
CATCGAGCAACTGCATGACCTGGGCATCAAAACCCTGATGCTCACCGGCGACAACGTCCACACCGCGCAGGCCATTGCCG
CGCAGGTCGGCATCGATGAAGCCAGGGGCGACCTGTTGCCGGGGGACAAATTGCAGTCTATCGAGGCCCTATATGCTCAG
GGGCACCGGGTCGGCATGGTCGGCGACGGCATCAACGACGCGCCTGCGCTGGCGCGTTCCGAGATCGGTTTCGCCATGGC
CGCCGCAGGCACCGATACCGCGATCGAAACCGCCGATGTCGCCCTGATGGACGATGATCTGCGCAAGATCCCGGCATTCA
TTCGTCTGTCGCGGCAGACGTCGAGCATCCTCAAACAGAACATTGCCCTGGCATTGGTCATCAAGGCGATCTTTCTTGGG
GTAACCTTCGCCGGGGTCGCTACCATGTGGATGGCAGTGTTCGCCGACATGGGCGTGAGTTTGCTGGTGGTGTTCAACGG
TTTGCGCCTGCTGCGCAAGTAA

Protein sequence :
MSDSQHTHKPVAEHEIGVKLRPLPKHDHGGHGDACCSSKTAAPARVTLSASPTAGARLSSFRIEAMDCPTEQTLIQNKLS
KLTGVQQLEFNLINRVLGVTHDLPGTEPITEAIKSLGMHAEPLEQGAETPAAKPDRKHWWPLALSGVGALLAEVIHFTAT
APDWMVAVIALVSILSGGLGTYKKGWIALKNLNLNINALMSIAVTGAVLIGQWPEAAMVMFLFTVAELIEARSLDRARNA
IGGLMQMAPEQATVLQADGSWVEQDVKIIEIGARVRVRPGERIGLDGEVLSGRSTIDQAPITGESLPVEKTVGDKVFAGT
INQAGSLEYAVTAVAGNSTLARIIHAVEQAQGARAPTQRFVDQFSKIYTPVVFVLALAVAVIPPLFMGALWFDWIYRALV
LLVVACPCALVISTPVTIVSGLAAAARKGILVKGGVYLEGGYKLDYLALDKTGTITHGKPVQTDYLSLDPTADASAPTIA
AALAGRSDHPVSLAIAKAAVDNQSATLIVDNFEALGGRGVRGEINGQLYHLGNHRLVEDLGLCSPALEEKLFALEKQGKS
VVLLLDSSGPLALFAVADTVKASSREAIEQLHDLGIKTLMLTGDNVHTAQAIAAQVGIDEARGDLLPGDKLQSIEALYAQ
GHRVGMVGDGINDAPALARSEIGFAMAAAGTDTAIETADVALMDDDLRKIPAFIRLSRQTSSILKQNIALALVIKAIFLG
VTFAGVATMWMAVFADMGVSLLVVFNGLRLLRK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ORF C97 AAN62190.1 putative metal-transporting P-type ATPase Not tested PAGI-2(C) Protein 0.0 67
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 7e-106 42
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 2e-106 41
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 2e-106 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
cadA1 YP_007032161.1 cadmium-translocating P-type ATPase BAC0298 Protein 0.0 67
cadA1 YP_007032161.1 cadmium-translocating P-type ATPase BAC0092 Protein 2e-66 41