Gene Information

Name : invC (PputUW4_03632)
Accession : YP_007030629.1
Strain : Pseudomonas sp. UW4
Genome accession: NC_019670
Putative virulence/resistance : Virulence
Product : secretory apparatus ATP synthase
Function : -
COG functional category : -
COG ID : -
EC number : 3.6.3.14
Position : 4217397 - 4218683 bp
Length : 1287 bp
Strand : -
Note : [NU] COG1157 Flagellar biosynthesis/type III secretory pathway ATPase

DNA sequence :
ATGAACATCCGGCTGCAACGGCACGGTGCCCATCCGTTGCGTTTGAGTGGTCCATTGATCGAGGCGGCGCTGGGCGACGT
GGTGATCGGTGAAGTCTGCGAAGTGCGTCGGCATTGGCGCTTGCCTGAGGTTGCGGCCAGGGCGCAGGTCATTGGCTTCA
AGCCCGGCGCGGTCGTGCTCAGTTTGCTCGGCGATGCCAAGGGCTTGTCCAGAGAGTCGATGATTGTTCCCACGGGCTCG
ATCCTGCAACTGACGTGCAGTGATGCCTTGCTCGGCAGCGTAGTCGACCCTCAAGGCGCTATCGTCGAGCGTCTGGCACC
GTCTACGGCGTTGGCGCAAGAGGACTATCCGGTGGACGCCGACCCGCCGTCATACCAGCAGCGGCGCCCGGTGGACACCC
CTTTGCGCACCGGTATTCGGGTCATCGACGGCTTGCTGACTTGCGGTATCGGCCAGCGCATCGGCATTTTCGCCGCCGCC
GGCTCCGGCAAAACCACCCTGATCAATATGCTGATCAACCACACCGACGCCGATGTGTTTGTCATTGGCCTGATCGGTGA
GCGCGGACGTGAAGTGACCGAATTCATCGAGCATCTGCGTCAGTCTGAAATACGCTCACGATGCGTGGTGGTGTATGCCA
CCTCGGATTTTTCCTCGGTGGATCGCTGCAACTCGGCCTTGCAGGCTACGGCTATCGCCGAGTATTTCCGTGACCAGGGC
CTGCGTGTGGTGTTGTTGCTGGATTCGTTGACGCGCTACGCCAGGGCCCGTCGCGATCTGGCCCTGGCCGCGGGAGAAGC
GCCGGCGCGACGAGGCTACCCGGCCTCGGTGTTCGATGCCTTGCCGCGCCTGCTGGAACGGCCCGGGGTGACTGCCTCCG
GCAGCATTACCGCCTGGTACACGGTGCTGCTGGAAAGTGACGACGAACCGGACCCGATCGCCGAGGAGATTCGCTCAATC
CTCGACGGCCATATTTACCTCAGCCGTGCGCTGGCGGCCAAGGGGCACTACCCGGCAATCGATGTGTTGCGCAGTGTCAG
TCGCGTGGCGACGCAAGTCACTGCGCCGCAGGTGCAGCAACTGGCGGCGGCGACCCGGGAAACGCTGACGCGGCTTGAGC
AGCTGCAGGTTTTTCTCGACATGGGCGAGTACAGCCCAGGCGCGGACGCTGCCAATGACCAGGCGCTGCAACGCCGTGAA
GCCCTCTACCAGTGGTTGCGCCAGCCCACGGGCGAACGCTGTGAACCGGACGAGGCCCTGGGCCAATTGCAGGGGGTCAT
GGCATGA

Protein sequence :
MNIRLQRHGAHPLRLSGPLIEAALGDVVIGEVCEVRRHWRLPEVAARAQVIGFKPGAVVLSLLGDAKGLSRESMIVPTGS
ILQLTCSDALLGSVVDPQGAIVERLAPSTALAQEDYPVDADPPSYQQRRPVDTPLRTGIRVIDGLLTCGIGQRIGIFAAA
GSGKTTLINMLINHTDADVFVIGLIGERGREVTEFIEHLRQSEIRSRCVVVYATSDFSSVDRCNSALQATAIAEYFRDQG
LRVVLLLDSLTRYARARRDLALAAGEAPARRGYPASVFDALPRLLERPGVTASGSITAWYTVLLESDDEPDPIAEEIRSI
LDGHIYLSRALAAKGHYPAIDVLRSVSRVATQVTAPQVQQLAAATRETLTRLEQLQVFLDMGEYSPGADAANDQALQRRE
ALYQWLRQPTGERCEPDEALGQLQGVMA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
invC AAS66861.1 InvC Not tested SSR-2 Protein 3e-110 62
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 2e-111 61
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 2e-111 61
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 2e-111 61
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 2e-111 61
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 5e-107 61
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 8e-94 55
lscN AAO18044.1 LscN Virulence TTSS locus Protein 8e-76 49
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 9e-74 49
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-72 49
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 9e-74 49
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 2e-71 49
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-71 49
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 6e-73 49
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 6e-73 49
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 8e-73 49
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 3e-73 48
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 4e-62 46
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 4e-62 46
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 2e-62 46
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 3e-62 46
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 4e-62 46
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 2e-57 46
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 2e-62 45
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 3e-53 44
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 7e-50 44
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 6e-51 44
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 6e-51 44
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 6e-53 44
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 3e-54 44
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 3e-54 44
escN AAC38383.1 EscN Virulence LEE Protein 7e-58 43
escN YP_003236088.1 translocator EscN Virulence LEE Protein 2e-57 43
escN AAC31513.1 L0034 Virulence LEE Protein 8e-58 43
escN NP_290268.1 hypothetical protein Virulence LEE Protein 1e-57 43
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 8e-58 43
ECs4568 NP_312595.1 EscN Virulence LEE Protein 1e-57 43
unnamed AAL06369.1 EscN Virulence LEE Protein 2e-56 43
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 5e-61 43
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 2e-55 43
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 1e-55 43
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 1e-55 43
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 6e-59 42
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 6e-59 42
escN CAI43874.1 EscN protein Virulence LEE Protein 1e-56 42
escN CAC81862.1 EscN protein Virulence LEE II Protein 1e-56 42
escN AAK26715.1 EscN Virulence LEE Protein 7e-57 42
escN YP_003223475.1 translocator EscN Virulence LEE Protein 2e-56 42
escN AAL57542.1 EscN Virulence LEE Protein 7e-57 42
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 1e-56 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
invC YP_007030629.1 secretory apparatus ATP synthase VFG0555 Protein 8e-112 61
invC YP_007030629.1 secretory apparatus ATP synthase VFG2459 Protein 6e-104 58
invC YP_007030629.1 secretory apparatus ATP synthase VFG1778 Protein 7e-93 58
invC YP_007030629.1 secretory apparatus ATP synthase VFG1008 Protein 7e-99 57
invC YP_007030629.1 secretory apparatus ATP synthase VFG0390 Protein 6e-74 50
invC YP_007030629.1 secretory apparatus ATP synthase VFG0192 Protein 9e-75 50
invC YP_007030629.1 secretory apparatus ATP synthase VFG0048 Protein 8e-76 47
invC YP_007030629.1 secretory apparatus ATP synthase VFG0515 Protein 2e-62 46
invC YP_007030629.1 secretory apparatus ATP synthase VFG2144 Protein 4e-66 45
invC YP_007030629.1 secretory apparatus ATP synthase VFG2499 Protein 4e-53 45
invC YP_007030629.1 secretory apparatus ATP synthase VFG0730 Protein 4e-58 43
invC YP_007030629.1 secretory apparatus ATP synthase VFG0812 Protein 4e-58 43
invC YP_007030629.1 secretory apparatus ATP synthase VFG1254 Protein 4e-55 43