Gene Information

Name : topB (PputUW4_03014)
Accession : YP_007030014.1
Strain : Pseudomonas sp. UW4
Genome accession: NC_019670
Putative virulence/resistance : Unknown
Product : DNA topoisomerase III
Function : -
COG functional category : -
COG ID : -
EC number : 5.99.1.2
Position : 3541858 - 3543804 bp
Length : 1947 bp
Strand : +
Note : [L] COG0550 Topoisomerase IA

DNA sequence :
ATGCGGCTGTACCTCTGTGAAAAACCTTCCCAGGCCAAAGACATTGCGGCAGTCCTCGGCGCCCGGCGCCGAGGCGATGG
CTGTTGGCTGGGAACGGATGTCACGGTGACCTGGTGCATCGGCCACCTGCTGGAAACCGCGCCGCCGGATGCCTACGACG
CGCGCTACAAGCGCTGGGTGCTGGCCGACCTGCCGATCATTCCCGAAAAGTGGAAAATGACCGTCAAGCCGCGCACCGCC
AGCCAGTACAAGGCGGTCAAGCGCCTGCTCGGTGAAGCGGCCGAACTGGTCATTGCCACGGACGCCGACCGTGAGGGCGA
GATGATCGCCCGGGAACTGGTGGAGCATTGCCGCTATCGCGGGCCGATCCGCCGCCTCTGGTTGTCGGCCCTGGATGATG
CGTCCATCCGCAAGGCTCTCGCGGCACTCAAACCGGGCAACGAGACGTTCAGCCTCTATCACTCGGCCCTGGGGCGTTCC
CGGGCCGACTGGCTGATCGGCATGAACATGAGCCGGCTGTTCACCTTGCTGGGGCGCCAGTCCGGCTATCAAGGCGTGCT
GCCGGTGGGCCGGGTGCAAACGCCGACCTTGCGCCTGGTAGTGGATCGCGATCGCAGCATTGCCGACTTTGTGCCCGTCC
CCTATTGGGCCATCGATGTGCAACTGCTGCACAACGGCACCGCATTCACGGCGCAATGGCGCGCGGCATCCGAGGTTTGC
GACGATCAGGACCGTTGCCTGAATCAGGCGCTGGCCCAACAAGCAGCAGACGCCATGCGCGGCGCGGCCAGTGCGCGGGT
GATCAAATTGCGCACCGAACGGATGCGCGAAGTGGCCCCGCTGCCGTTCGACCTGGGCACCCTGCAGGAGGTCTGCTCAA
AGAAACTCGGCCTCGGCGCCCAGGAAACCCTCGACATTGCCCAGGCGCTTTACGAAACCTACAAGGTCATCACCTATCCG
CGCAGCGATTGCGGCTACTTGCCCCTCAGCCAGCACAACGAGGCACCGGCCATTCTGGCGGCGCTGCGCCAGGCCGACCC
GGCGTTGAACACCTTGCACGATCACCTTGATCCGCAACGGCGCTCACGGGCCTGGAACGATGCCAAGGTCAGCGCTCACC
ACGGCATCATCCCCACCGCGGCGGCGAAGAACCTCGACAAGCTGGCGGGCAAGCAGCGCGCGGTCTACACACTGATCCGC
GCGCGGTATCTGGCGCAGTTCCTGCCCAATCACGAATACGACCGCACCCAGGCCGACTTCGATTGCGCAGGCCAAGCCTT
GCGCGCTGTCGGCAAGCAGATCATCGAGCAGGGCTGGAAACGCGCCCTGCCCGAGGCACTGGCTGCGACCAAGGGACGCG
AAGCTCCAGCGCCACAGACACTGCCCAACCTGGCCGAAGGCATCGATTGCGCAGTGGCCGGCGTGCAACTCAAGGACCTC
TGGACGCAACCGCCAAAGCCGTTCACCGAAGGCGATCTGATCAAGGCCATGAAGAACGTCGCCAAACTGGTGGAAGACCC
GCTGCTCAAGCAAAAGCTCAAGGACACCACCGGCATCGGCACCGAAGCGACCCGTGCGTCGATCATCCAGGGCCTGCTCG
ACCGTGGCTATCTGGTCAAGAACGGCAAGGCCCTGGCCGCCACGCCGGCTGCGTTCAGCCTGATCGACGCCGTGCCGCGG
GCCATTGCCGACCCGGGCACCACGGCGATCTGGGAACAGGCCCTGGACATGGTGCAAAGCGGTGAAATGAGTCTTGAAGA
GTTCGTCACCAAACAGGCGGCGTGGATGAGCAAGCAGGTCAGCCGTTGCGCCGGACTGAGCCTGACCATCAGCGGTCCGC
CGCCTAACGGATCTGCCGCAGCCCCCTGGAAGAAAAAACGCAAGAGCGCCCCGCGCAAACCAGCGAGCGGCACCAAGCGC
AGGGCAAAACCGGCAAGCAAGACTTAA

Protein sequence :
MRLYLCEKPSQAKDIAAVLGARRRGDGCWLGTDVTVTWCIGHLLETAPPDAYDARYKRWVLADLPIIPEKWKMTVKPRTA
SQYKAVKRLLGEAAELVIATDADREGEMIARELVEHCRYRGPIRRLWLSALDDASIRKALAALKPGNETFSLYHSALGRS
RADWLIGMNMSRLFTLLGRQSGYQGVLPVGRVQTPTLRLVVDRDRSIADFVPVPYWAIDVQLLHNGTAFTAQWRAASEVC
DDQDRCLNQALAQQAADAMRGAASARVIKLRTERMREVAPLPFDLGTLQEVCSKKLGLGAQETLDIAQALYETYKVITYP
RSDCGYLPLSQHNEAPAILAALRQADPALNTLHDHLDPQRRSRAWNDAKVSAHHGIIPTAAAKNLDKLAGKQRAVYTLIR
ARYLAQFLPNHEYDRTQADFDCAGQALRAVGKQIIEQGWKRALPEALAATKGREAPAPQTLPNLAEGIDCAVAGVQLKDL
WTQPPKPFTEGDLIKAMKNVAKLVEDPLLKQKLKDTTGIGTEATRASIIQGLLDRGYLVKNGKALAATPAAFSLIDAVPR
AIADPGTTAIWEQALDMVQSGEMSLEEFVTKQAAWMSKQVSRCAGLSLTISGPPPNGSAAAPWKKKRKSAPRKPASGTKR
RAKPASKT

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
topB AAN62317.1 putative DNA topoisomerase III Not tested PAGI-3(SG) Protein 0.0 65
topB AAN62194.1 putative DNA topoisomerase III Not tested PAGI-2(C) Protein 0.0 63
pph56 CAI36097.1 Topoisomerase IA Not tested PPHGI-1 Protein 0.0 61
topB NP_458624.1 topoisomerase B Not tested SPI-7 Protein 3e-149 50
topB NP_807836.1 DNA topoisomerase III Not tested SPI-7 Protein 3e-149 50
topB AAF14809.1 topoisomerase B Not tested SPI-7 Protein 2e-149 50
PMI2630 YP_002152332.1 DNA topoisomerase III Not tested Not named Protein 3e-149 50
topB1 YP_005176228.1 DNA topoisomerase III Not tested ICEPmu1 Protein 4e-144 49
topB AAW83109.1 TopB Not tested GGI Protein 2e-113 42