Gene Information

Name : ureB (HPAKL86_05685)
Accession : YP_007019189.1
Strain : Helicobacter pylori Aklavik86
Genome accession: NC_019563
Putative virulence/resistance : Virulence
Product : urease subunit beta
Function : -
COG functional category : -
COG ID : -
EC number : 3.5.1.5
Position : 1195963 - 1197672 bp
Length : 1710 bp
Strand : +
Note : COG0804 Urea amidohydrolase (urease) alpha subunit

DNA sequence :
ATGAAAATGAAAAAACTTGATTATGTCAATACTTACGGGCCCACTAAAGGGGATAAAGTAAGATTAGGCGATACAGAGAT
TTGGGCAGAAGTGGAGCATGATTATACCATCTATGGTGAAGAGTTAAAATTTGGTGCAGGCAAGACTATCAGAGAAGGCA
TGGGGCAAAGCAACAGCCATGACGAGAACACTTTGGATCTAGTGATCACCAACGCTCTCATTATTGATTACACCGGCATT
TACAAAGCTGATATTGGGATCAAAAACGGCAAGATTGCAGGCATTGGTAAAGCAGGCAATAAAGACATGCAAGATGGCGT
CAGCCCTAATTTAGTTGTAGGCGTAGGCACAGAAGCTTTAGCGGGCGAAGGCATGATTGTAACCGCTGGTGGGATTGATA
GCCACACGCATTTTTTAAGCCCTCAACAATTCCCCACAGCTCTAGCTAATGGCGTGACTACGATGTTTGGCGGTGGGACT
GGTCCGGTAGATGGCACGAATGCGACCACTATCACTCCAGGAGAATGGAATATCCACAGAATGTTAAGAGCCGCTGAAGA
ATACGCCATGAATGTGGGGTTTTTAGGGAAAGGGAATTCTTCTAGCAAAACCCAATTAGTGGAACAAATTGAAGCGGGCG
TTGTAGGCTTTAAATTGCACGAAGATTGGGGCACCACTCCTAGCGCGATTGATACATGCTTAAGCGTCGCTGATGAATAC
GATGTGCAAGTGTGCATCCATACAGACACCGTGAATGAAGCCGGGTATGTGGAAGACACGCTCAATGCAATGAACGGACG
CGCTATCCATGCATACCACATTGAAGGGGCAGGCGGAGGACATAGCCCAGATGTTATCACTATGGCCGGTGAAGAAAACA
TCTTACCCAGTTCCACCACCCCAACCATTCCTTATACCATAAATACGGTTGCAGAACACTTAGACATGCTAATGACATGC
CATCATTTGGATAAAAAAATCCGAGAAGATTTACAATTTTCCCAAAGCCGTATCCGCCCGGGCAGCATTGCAGCTGAAGA
TGTTTTACATGACAATGGCATGATTGCTATGACAAGTTCGGATTCTCAAGCGATGGGGAGAGCGGGTGAAGTCGTTCCAA
GAACTTGGCAAACCGCTGACAAAAACAAAAAAGAGTTTGGTCCTTTAAAAGAAGACGCTCAAAACGGGAATGATAATTTC
CGCATCAAACGCTACATTTCTAAATACACCATCAACCCGGCTATTACGCACGGCGTGAGCGAATACATAGGCTCTGTGGA
AGCGGGGAAAATCGCTGATTTAGTCGTGTGGAATCCGGCCTTTTTTGGGGTGAAACCTAAGATCATTATTAAAGGCGGTT
TGGTCGTGTTCTCTGAAATGGGCGATAGCAACGCTTCTGTGCCAACCCCACAACCTGTTTATTACAGAGAAATGTTTGGT
CATCATGGGAAGGCTAAGTTTGACACGAGCATCACTTTTGTCAATAAGCTCGCCTATGAAAAGGGCATCAAAGAAAAACT
TGGCTTAGAAAGACAAGTATTGCCCATCAAAAATGTGCGCAACATCACTAAAAAAGACTTTAAATTCAACAACACGACAG
GAAAACTCACCGTCGATCCCAAAACCTTTGAAGTCTTTTTAGATGGCAAGCTTTGCACTTCCAAGCCAGCGAGCGAATTG
CCTTTAGCGCAACGCTACACTTTCTTTTAA

Protein sequence :
MKMKKLDYVNTYGPTKGDKVRLGDTEIWAEVEHDYTIYGEELKFGAGKTIREGMGQSNSHDENTLDLVITNALIIDYTGI
YKADIGIKNGKIAGIGKAGNKDMQDGVSPNLVVGVGTEALAGEGMIVTAGGIDSHTHFLSPQQFPTALANGVTTMFGGGT
GPVDGTNATTITPGEWNIHRMLRAAEEYAMNVGFLGKGNSSSKTQLVEQIEAGVVGFKLHEDWGTTPSAIDTCLSVADEY
DVQVCIHTDTVNEAGYVEDTLNAMNGRAIHAYHIEGAGGGHSPDVITMAGEENILPSSTTPTIPYTINTVAEHLDMLMTC
HHLDKKIREDLQFSQSRIRPGSIAAEDVLHDNGMIAMTSSDSQAMGRAGEVVPRTWQTADKNKKEFGPLKEDAQNGNDNF
RIKRYISKYTINPAITHGVSEYIGSVEAGKIADLVVWNPAFFGVKPKIIIKGGLVVFSEMGDSNASVPTPQPVYYREMFG
HHGKAKFDTSITFVNKLAYEKGIKEKLGLERQVLPIKNVRNITKKDFKFNNTTGKLTVDPKTFEVFLDGKLCTSKPASEL
PLAQRYTFF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 1e-139 58
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 2e-143 58
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 2e-143 58
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 2e-139 58
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 2e-139 58
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 2e-139 58

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ureB YP_007019189.1 urease subunit beta VFG0270 Protein 0.0 73