Gene Information

Name : guaA (HPAKL86_05580)
Accession : YP_007019168.1
Strain : Helicobacter pylori Aklavik86
Genome accession: NC_019563
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : -
COG ID : -
EC number : 6.3.5.2
Position : 1172683 - 1174209 bp
Length : 1527 bp
Strand : -
Note : COG0518 GMP synthase - Glutamine amidotransferase domain

DNA sequence :
ATGATTTTAGTATTAGATTTTGGGAGCCAATACACACAGCTGATTGCTAGAAGATTGAGAGAGAGCGGGATTTATGCAGA
AATAGTCCCTTTTTTTGAAAGCATAGAAAACATTCAAAAAAAAGCCCCTAAAGGTTTGATTTTGAGTGGGGGGCCAGCGA
GCGTGTATGCTAAAGACGCTTACAAGCCCAATGAAAAAATCTTTGATTTGGATTTGCCGATTTTAGGGATTTGCTACGGC
ATGCAGTATTTGGTGGATTTTTTTGGGGGGGTAGTGGCTTGCGCGAACGAGCAAGAATTTGGTAAGGCTGTCTTAGAAAT
CACTCAAGATTCTGTGATTTTTGAAGGCGTGAAAATTAAAAGCCTTGTGTGGATGAGCCATATGGATAAAGTCATAGAAT
TGCCTAAAGGCTTCACTACCCTTGCAAAAAGCCCTAATTCCCCCCATTGCGCGATTGAAAACGCTAAGATTTTTGGCTTA
CAATTCCACCCAGAAGTCATTCAAAGCGAAGAAGGGGGTAAGATTTTAGAGAATTTTGCCCTTTTGGTTTGCGGCTGTGA
AAAAACTTGGGGGATGCAGCATTTCGCTCAAAGAGAAATGGCGCGATTGAAAGAAAAAATTGCTAACGCTAAGGTTTTGT
GCGCGGTGAGTGGGGGCGTGGATTCTACGGTGGTCGCTACGCTATTACACAGAGCCATTAAGGATAATTTGATCGCTGTT
TTTGTAGATCATGGTTTGTTGCGTAAAAATGAAAAAGAAAAAGTTCAAGCGATGTTTAAAGACTTGCAAATCCCTTTAAA
CACGATAGACGCTAAAGAAATCTTTTTGTCTAAATTAAAGGGCACAAGCGAGCCTGAATTGAAGCGAAAAATCATCGGCG
AAACCTTTATTGAAGTGTTTGAAAAAGAAGCCAAGAAGCACCATTTAAAAGGCAAAATTGAGTTTTTAGCCCAAGGCACT
TTATACCCTGACGTGATTGAATCCGTGAGCGTTAAAGGGCCTTCAAAAGTGATCAAAACCCACCATAATGTGGGCGGACT
GCCTGAATGGATGGACTTTAAACTCATAGAGCCTTTAAGGGAATTGTTTAAAGATGAGGTGCGTTTGTTGGGTAAGGAAT
TGGGCATTAGCCAGGATTTTTTGATGCGCCACCCCTTTCCAGGGCCTGGGCTTGCGATAAGGATTTTAGGCGAAGTTAGC
GAGAGTAAGATCAGATGCTTGCAAGAAGCGGATTTTATTTTTATAGAAGAGCTTAAAAAGGCGGATCTGTATGACAAGGT
TTGGCAGGCTTTTTGCGTGCTATTGAATGTCAATTCTGTGGGGGTTATGGGGGATAATCGCACTTATGAAAACGCTATTT
GCTTAAGAGCGGTGAATGCGAGCGATGGCATGACAGCGAGCTTTTCATTTTTAGAGCATTCTTTTTTAGAAAAGGTTTCT
AATCGTATCACTAATGAAGTGAGCGGTATCAATAGGGTGGTGTATGACATTACCTCTAAGCCACCAGGAACGATTGAATG
GGAATGA

Protein sequence :
MILVLDFGSQYTQLIARRLRESGIYAEIVPFFESIENIQKKAPKGLILSGGPASVYAKDAYKPNEKIFDLDLPILGICYG
MQYLVDFFGGVVACANEQEFGKAVLEITQDSVIFEGVKIKSLVWMSHMDKVIELPKGFTTLAKSPNSPHCAIENAKIFGL
QFHPEVIQSEEGGKILENFALLVCGCEKTWGMQHFAQREMARLKEKIANAKVLCAVSGGVDSTVVATLLHRAIKDNLIAV
FVDHGLLRKNEKEKVQAMFKDLQIPLNTIDAKEIFLSKLKGTSEPELKRKIIGETFIEVFEKEAKKHHLKGKIEFLAQGT
LYPDVIESVSVKGPSKVIKTHHNVGGLPEWMDFKLIEPLRELFKDEVRLLGKELGISQDFLMRHPFPGPGLAIRILGEVS
ESKIRCLQEADFIFIEELKKADLYDKVWQAFCVLLNVNSVGVMGDNRTYENAICLRAVNASDGMTASFSFLEHSFLEKVS
NRITNEVSGINRVVYDITSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 2e-133 53
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 1e-133 53
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 1e-133 53
guaA NP_938969.1 GMP synthase Not tested Not named Protein 1e-114 47