Gene Information

Name : HPAKL117_01315 (HPAKL117_01315)
Accession : YP_007016815.1
Strain : Helicobacter pylori Aklavik117
Genome accession: NC_019560
Putative virulence/resistance : Virulence
Product : ATP-dependent protease binding subunit (clpB)
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 264056 - 266626 bp
Length : 2571 bp
Strand : +
Note : COG0542 ATPases with chaperone activity, ATP-binding subunit

DNA sequence :
ATGAATTTATTTGAAAAAATGACTGACCAATTGCATGAAACTTTAGACAGCGCGCTCGCTCTAGCCTTACACCATAAAAA
CGCTGAAGTAACGCCCTTGCACATGCTTTTTGTCATGCTCAATAACTCCCAAGGCATCCTCATTCAAGCCTTACAAAAAA
TGTCTGTGGATATTCAAGCCTTAAGGCTTAGCGTTCAAAGCGAGTTGAATAAGTTTGCTAAAGTTTCACAAATCAACAAG
CAAAATATCCAATTAAACCAAGCTCTAATCCAAAGTTTAGAAAACGCTCAAGGCTTGATGGCTAAAATGGGCGATTCTTT
CATCGCTACAGATGTGTATCTTTTGGCGAACATGAGCCTTTTTGAAAGCGTTCTAAAACCTTATTTAGACACTAAAGAAT
TGCAAAAAACTTTAGAGGCTTTGAGAAAAGGCGCGACTATCCAAAGTAAAAACGATGATTCTAATTTGGAAAGTTTGGAA
AAATTTGGCATTGATTTGACGCAAAAAGCCCTAGAAAATAAGCTCGATCCGGTGATCGGGAGGGATGAAGAAATCATTCG
CATGATGCAAATTTTGATAAGAAAAACAAAAAATAACCCTATTTTACTGGGTGAGCCTGGAGTGGGGAAAACGGCGGTTG
TGGAGGGTTTGGCCCAACGCATTGTGAATAAGGAAGTGCCTAAAACGCTTTTAAACAAACGAGTCGTCGCTTTAGATTTA
AGCTTGTTGGTGGCTGGAGCCAAATACAGAGGCGAGTTTGAAGAGCGTTTGAAAAAGGTGATTGAAGAAGTTAAAAAAAG
CGCGAATGTGATTTTATTCATTGATGAAATCCACACGATCGTAGGGGCTGGAGCTAGTGAGGGGGGCATGGATGTGGCTA
ATATTTTAAAACCCGCGCTCGCTAGGGGGGAATTGCACACGATTGGAGCGACCACTTTGAAAGAATACCGCAAGTATTTT
GAAAAAGACATGGCACTACAAAGGCGTTTCCAACCCATTTTACTCAATGAGCCTAGCATCAATGAAGCCTTACAGATTTT
AAGGGGGTTAAAAGAAACTTTAGAAACGCACCATAATATCACTATCAACGACTCCGCGCTCATAGCGAGCGCCAAACTCT
CTAGCCGTTATATCACCGATAGGTTTTTACCCGATAAAGCGATTGATTTGATTGATGAGGGGGCGGCCCAATTAAAAATG
CAAATGGAATCTGAGCCGGCAAAACTCTCTAGCGTTAAACGCTCCATTCAAAGATTAGAAATGGAAAGACAAGCCCTTGA
AATGGAAAAAAAAGAGAGCAATGCCAAACGCATGCAAGAAATCCTTAAAGAATTGAGCGACTTGAAAGAAGAAAAAATCC
AATTAGAAGCGCAATTTGAAAACGAAAAAGAAGTGTTTAGAGAAATTTCACGCTTGAAAATGGAAACGGAAAGCTTGAAA
AAAGAGGCTGAGAGGTTTAAGCGCAATGGGGATTACCAGCAAGCGGGTGAAATTGAATACTCTAAAATCCCTGAAAACAA
AAAGAAAGAAGAAGAATTGCAGCATAAATGGGAAGCGATGCAACAAAACGGGGCGTTATTGCAAAACGCTTTAACCGAAA
ACAACATCGCTGAGATCGTGAGCCAATGGACGCATATACCGGTCCAAAAAATGCTCCAAAGCGAAAAAAATAGGGTTTTA
AACATTGAAAGCGAATTGCAAAAAAGAGTGGTGGGGCAAGAAAAAGCGATCAAAGCGATCGCTAAAGCGATTAAAAGGAA
TAAGGCCGGGCTTAGCGATAGCAATAAACCCATAGGGAGTTTTCTTTTTTTAGGGCCAACGGGCGTGGGTAAAACCGAGA
GCGCTAAAGCTTTGGCGCAATTCTTGTTTGATAGCGATAAAAATCTTATAAGAATTGACATGAGCGAATACTTAGAAAAG
CATGCCATAAGCCGTCTTATTGGGGCCGCTCCTGGGTATGTGGGCTATGAAGAAGGCGGGCAATTGACCGAAGCGGTGCG
CAGAAAACCCTATAGCGTGGTGCTGTTAGATGAAGTGGAAAAAGCCCATCCGGATGTGTTTAACCTTTTGTTGCAGGTTT
TAGATGAAGGGCATTTAACCGATAGTAAGGGCGTGAGGGTGGATTTCAAAAACACGATTTTGATTTTAACCAGCAATGTG
GCTAGTGGTGTGCTTTTAGAAGAGATTTTGAGTGAAGCCGATAAACAAAAAGCGATCAAAGAGAGTTTGAGGCAATTCTT
CAAGCCGGAATTTTTAAACCGCTTAGATGAAATCATCTCCTTTAACGCCCTAGATAGCCATGCTATCGCTAATATCGTGG
GGATTCTCTTTGAAAACATTCAAAAAAAAGCGCTTGAAAGAGGTATTAATATAACCCTAGACGAAGAGGCAAAAGAATTG
ATCGCCAAAGCGGGATTTGACAGATTCTATGGTGCTAGACCCTTGAAGCGCGCGCTCTATGAAATGGTAGAAGACAAGCT
CGCTGAACTCATTTTAGAGGATAAAATTAAAGAGAATGACAGCGTGGCGTTTGTGGTAGAAAATAACGAAATTGTGCCTA
AGATTAAGTGA

Protein sequence :
MNLFEKMTDQLHETLDSALALALHHKNAEVTPLHMLFVMLNNSQGILIQALQKMSVDIQALRLSVQSELNKFAKVSQINK
QNIQLNQALIQSLENAQGLMAKMGDSFIATDVYLLANMSLFESVLKPYLDTKELQKTLEALRKGATIQSKNDDSNLESLE
KFGIDLTQKALENKLDPVIGRDEEIIRMMQILIRKTKNNPILLGEPGVGKTAVVEGLAQRIVNKEVPKTLLNKRVVALDL
SLLVAGAKYRGEFEERLKKVIEEVKKSANVILFIDEIHTIVGAGASEGGMDVANILKPALARGELHTIGATTLKEYRKYF
EKDMALQRRFQPILLNEPSINEALQILRGLKETLETHHNITINDSALIASAKLSSRYITDRFLPDKAIDLIDEGAAQLKM
QMESEPAKLSSVKRSIQRLEMERQALEMEKKESNAKRMQEILKELSDLKEEKIQLEAQFENEKEVFREISRLKMETESLK
KEAERFKRNGDYQQAGEIEYSKIPENKKKEEELQHKWEAMQQNGALLQNALTENNIAEIVSQWTHIPVQKMLQSEKNRVL
NIESELQKRVVGQEKAIKAIAKAIKRNKAGLSDSNKPIGSFLFLGPTGVGKTESAKALAQFLFDSDKNLIRIDMSEYLEK
HAISRLIGAAPGYVGYEEGGQLTEAVRRKPYSVVLLDEVEKAHPDVFNLLLQVLDEGHLTDSKGVRVDFKNTILILTSNV
ASGVLLEEILSEADKQKAIKESLRQFFKPEFLNRLDEIISFNALDSHAIANIVGILFENIQKKALERGINITLDEEAKEL
IAKAGFDRFYGARPLKRALYEMVEDKLAELILEDKIKENDSVAFVVENNEIVPKIK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 1e-140 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
HPAKL117_01315 YP_007016815.1 ATP-dependent protease binding subunit (clpB) VFG0079 Protein 1e-158 43
HPAKL117_01315 YP_007016815.1 ATP-dependent protease binding subunit (clpB) VFG2076 Protein 2e-112 42