Gene Information

Name : lysS (F92_10530)
Accession : YP_007009975.1
Strain : Francisella tularensis F92
Genome accession: NC_019537
Putative virulence/resistance : Virulence
Product : lysyl-tRNA ligase
Function : -
COG functional category : -
COG ID : -
EC number : 6.1.1.6
Position : 1824893 - 1826623 bp
Length : 1731 bp
Strand : -
Note : COG1190 Lysyl-tRNA synthetase (class II)

DNA sequence :
TTGGGGCTACTAATTGCTAATGTGCAACAAATAATTACAGGGTTTAAAATGAGTAGTAAATTAAAAGATTTGATAAAAAC
AACGATAAAAGAATATTTAGAAGCTAATGATATCACAGTTAAAGATGCTATTAGAGGCAAGATTAGAGAGCAGATTAGTG
AGTTTTTAGGCGAGGTAAGCGAGATAAATGAGCAGGTTAAAGAACAAATTTCAGCGCTTGTGAAAAAGCATGTAACAGAA
TTACAAGAAAGCTCACAAATTGCTTTAAGAAAAGAAAAGCTAAAAACTTTAGCTCAGCAAAATAATGGCATAAGCCATCC
AAATAGTTTCCGAAGAAATGCTGTTGCTATAGAGTTACAGGCTCGCTATACTGATAAGACTAAGCAAGAATTAGAAGAGC
TAGATAATAAACAACAATATAGTTTGACAGGTAGAGTAGTTCTACGCCGTGTCATGGGTAAAGCATCTTTTATAACACTA
CAAGATTATACTGGTAGAATCCAAGTTTATCTAAAAAAGAGTGACTTGCCAGATGGGCAATATGAAACTTTTAAGAATCT
ATGTGACTTGGGTGATATAGTTGGTATTACTGGTACTATGTTTAAGACAAATACTGGTGAACTTTCTGTTGAAGCAAATC
ACTTTGAGATTTTGACAAAGGCAATTCGTCCTTTGCCTGATAAATTCCATGGTTTGGCAGATCAAGAAATGAGATATCGT
CAAAGATATGTTGATTTAATTACAAATGAAAAGGCAAGAGAAGTCTTTAAAGTACGCTCAAAAGTTGTGAGCTTTATCCG
TAACTACTTTGATAGACTAGATTTTATGGAAGTAGAGACGCCGATGATGCATGTTTTGCAAGGTGGTGCTGCTGCTAAGC
CATTTAAAACTCATCACAATGCTTTGGATATGCCTTTATATTTGCGTATTGCTCCAGAACTTTATCTAAAAAGACTAGTT
GTTGGTGGTTTTGAGCGAGTTTATGAGATAAACCGTAATTTTAGAAACGAAGGTATATCTTCACGCCATAATCCAGAATT
TACAATGCTAGAGTTCTATATGGCGTATGCTGATTATAATGACCTTATGGATCTAACAGAAGATATGCTATCTAAACTTG
TACAGGAAGTAATTGGTAGCGAGATACTTGAGTATGGTGAGTATAAAATCAACTTTGGTGGTAAGTACGAACGAATCTCC
ATGGTTGACTCAATTGTTAAGTATAATGATGATATTACCAAAGAAGATTTAGTAACATTTGAATCTGCTAAAAAGATTGC
TGAGAAACTAAAAATAAAAGTTGAAGCTTACCATGAACTTGGACATTTGATAAACGAAATATTTGAAGAAACTGTCGAGC
ATCAGCTTATTCAACCGACATTTATTACAGATTATCCAGCTGTAGTTTCACCATTGGCGCGTAGACAAGACGGTAACCCT
GAGTTTACCGATAGATTTGAGTTCTTTATTGGAGCACGTGAAGTTGCTAACGGCTTCTCTGAGCTAAATGATGCTGAAGA
TCAAGCAGAGCGTTTCAGAAAACAGGTTGAAGCTGCGGCATCTGGAGATGATGAAGCTATGCCTTATGACAAAGACTATA
TTCGCGCACTAGAGTATGGTATGCCTCCTACAGCGGGACAAGGAATCGGTATTGATAGACTGGTAATGTATCTAACAAAC
TCTCAATCAATTAGAGATGTGATTCTATTTCCGCATATGAAGCCTGAGTAA

Protein sequence :
MGLLIANVQQIITGFKMSSKLKDLIKTTIKEYLEANDITVKDAIRGKIREQISEFLGEVSEINEQVKEQISALVKKHVTE
LQESSQIALRKEKLKTLAQQNNGISHPNSFRRNAVAIELQARYTDKTKQELEELDNKQQYSLTGRVVLRRVMGKASFITL
QDYTGRIQVYLKKSDLPDGQYETFKNLCDLGDIVGITGTMFKTNTGELSVEANHFEILTKAIRPLPDKFHGLADQEMRYR
QRYVDLITNEKAREVFKVRSKVVSFIRNYFDRLDFMEVETPMMHVLQGGAAAKPFKTHHNALDMPLYLRIAPELYLKRLV
VGGFERVYEINRNFRNEGISSRHNPEFTMLEFYMAYADYNDLMDLTEDMLSKLVQEVIGSEILEYGEYKINFGGKYERIS
MVDSIVKYNDDITKEDLVTFESAKKIAEKLKIKVEAYHELGHLINEIFEETVEHQLIQPTFITDYPAVVSPLARRQDGNP
EFTDRFEFFIGAREVANGFSELNDAEDQAERFRKQVEAAASGDDEAMPYDKDYIRALEYGMPPTAGQGIGIDRLVMYLTN
SQSIRDVILFPHMKPE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 4e-138 56
lysS YP_005163386.1 lysyl-tRNA synthetase Not tested Not named Protein 6e-85 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_007009975.1 lysyl-tRNA ligase VFG1668 Protein 2e-138 56