Gene Information

Name : guaA (F92_05915)
Accession : YP_007009193.1
Strain : Francisella tularensis F92
Genome accession: NC_019537
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : -
COG ID : -
EC number : 6.3.5.2
Position : 1021285 - 1022835 bp
Length : 1551 bp
Strand : +
Note : COG0518 GMP synthase - Glutamine amidotransferase domain

DNA sequence :
ATGACAGATATACATAATCATAAGATTTTGATTTTAGATTTTGGCTCGCAATATACACAACTTATTGCTCGTAGAGTAAG
AGAAGTAGGTGTTTTTTGTGAAATTTTCCCTCATGATGTAGCAGCTGATTTTATCAAAAATTATCAAGCAAAAGGAATAA
TTTTATCAGGTGGTCCTGAGTCAGTTTATGATTCTGATGTCAAAGCTCCTGAGATAGTTTTTGAGCTTGGAGTACCTGTT
TTGGGTATTTGTTATGGCATGCAAACAATGGTAATGCAGCATGGTGGCGAAGTAAAAGGAGCTGATCAAAGTGAATTTGG
TAAGGCAATTATAAATATCCTAAATTTAACAAATAACATATTTTCAAATATGGAGCATGAGCAGCTAGTTTGGATGAGTC
ATAGTGACAAAGTCACTCAAACTGGTGAGCATTTTGAGATAATTGCTTCTTCAACAAATGCTCCAGTTGCGGCAGTTGCA
CATAAAAATAAGCCTTTTTTTGGTGTGCAGTTTCACCCAGAAACTACTCATACAGAAAATGGTAAGCAAATTATTGAGAA
TTTTGTCGTTAATATCTGCGGATGTGATACTCTGTGGAATATCGAAAACATTATCGAAAATGATATAAAAGAAATTAAAC
AAAAAGTTGGTACTGATAAAGTAATTTTAGGGCTATCTGGAGGTGTTGATTCATCTGTTGTAGCTGCGATATTACATCAA
GCTATCGGCGATCAGCTAACTTGTATATTTGTAGATACTGGTTTACTGCGCCTTAATGAGGGTGATCAAGTTATGCAAGT
ATTTGCAGAGCATATGGATATTAATGTTATTCGTATCAATGCAAAAAATAGATTCTTAGATGCCCTAAGGGGTATCTGTG
ATCCAGAACAAAAACGTAAAATTATCGGTAAGCTATTTGTTGATATTTTTGATGAAGAGGCTGCTAAGATAGAGAATGCT
AAATGGCTTGCGCAGGGCACTATCTACAGTGATGTAATTGAATCAGCTGGCAATAATCAGTCTAAAGCACATGTAATTAA
ATCACATCATAATGTTGGTGGCTTACCAAAAGAAATGAAACTTAAGCTTTTAGAACCATTAAGAGAGCTTTTCAAAGATG
AGGTTCGTAAATTAGGCTTAGGTTTAGGATTACCTTATAATATGCTTTATAGACATCCATTTCCTGGTCCTGGTCTTGGA
GTACGTATATTAGGTGAAATAAAGAAAGAGTATGTAGAAACGTTACAAAAAGCTGATGCTATATTTACAGAAGAGCTTTA
TAAACATAATTTATACCATGATGTTTCTCAAGCTTTTGGGGTGTTTTTACCTATCAAATCGGTAGGTGTAGTTGGTGATC
AGCGTAGATATGAGTATGTAATAGCTCTAAGAGCTGTCGTTAGTATCGATTTTATGACTGCAACGTGGGCTAATTTACCT
TATGATTTTCTGTCACTAGTTTCAAATAGAATTGTAAATGAAGTAAAACAAGTATCAAGAGTTGTGTATGATGTGACAGG
AAAACCACCTGGAACAATTGAATGGGAATAA

Protein sequence :
MTDIHNHKILILDFGSQYTQLIARRVREVGVFCEIFPHDVAADFIKNYQAKGIILSGGPESVYDSDVKAPEIVFELGVPV
LGICYGMQTMVMQHGGEVKGADQSEFGKAIINILNLTNNIFSNMEHEQLVWMSHSDKVTQTGEHFEIIASSTNAPVAAVA
HKNKPFFGVQFHPETTHTENGKQIIENFVVNICGCDTLWNIENIIENDIKEIKQKVGTDKVILGLSGGVDSSVVAAILHQ
AIGDQLTCIFVDTGLLRLNEGDQVMQVFAEHMDINVIRINAKNRFLDALRGICDPEQKRKIIGKLFVDIFDEEAAKIENA
KWLAQGTIYSDVIESAGNNQSKAHVIKSHHNVGGLPKEMKLKLLEPLRELFKDEVRKLGLGLGLPYNMLYRHPFPGPGLG
VRILGEIKKEYVETLQKADAIFTEELYKHNLYHDVSQAFGVFLPIKSVGVVGDQRRYEYVIALRAVVSIDFMTATWANLP
YDFLSLVSNRIVNEVKQVSRVVYDVTGKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 3e-119 54
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 2e-119 54
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 2e-119 54
guaA NP_938969.1 GMP synthase Not tested Not named Protein 3e-98 45