Gene Information

Name : metC (uc509_0794)
Accession : YP_006999213.1
Strain : Lactococcus lactis UC509.9
Genome accession: NC_019435
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase/cystathionine beta-lyase
Function : -
COG functional category : -
COG ID : -
EC number : 4.4.1.1
Position : 780555 - 781697 bp
Length : 1143 bp
Strand : +
Note : -

DNA sequence :
ATGACAAGTTTAAAAACAAAAGTAATTCACGGTGGAATTTCAACAGATAGAACAACAGGAGCTGTTTCTGTTCCAATTTA
TCAAACATCAACTTATAAACAAAATGGACTTGGACAACCTAAAGAATATGAATATTCACGTTCAGGTAATCCGACACGAC
ATGCTTTGGAAGAATTAATTGCAGATTTAGAGGGTGGGGTTCAAGGTTTTGCTTTTAGTTCAGGCTTGGCTGGAATTCAC
GCGGTACTATCTTTATTTTCTACGGGCGATCATATCATCTTAGCTGATGATGTTTATGGCGGAACTTTTCGATTGATGGA
CAAGGTGCTGACAAAGACAGGAATAATCTATGATTTAGTAGATTTGAGCAATCTTGAAGATTTAAAGGCAGCTTTTAAAG
CAGAAACCAAAGCAGTCTACTTTGAAACTCCCTCAAATCCCCTGCTAAAAGTCTTGGATATCAAAGAAATTTCAAGCATT
GCTAAAGCTCATAATGCTCTAACATTAGTTGATAATACCTTTGCGACGCCTTATTTACAACAACCAATCGCTCTAGGAGC
GGATATTGTCTTGCATTCTGCAACGAAATATTTAGGAGGACACTCAGATGTAGTGGCTGGTTTGGTAACGACAAATTCAA
ATGAACTCGCTAGTGAAATTGGCTTTTTACAAAATTCTATTGGAGCGGTTCTTGGTCCACAAGATAGCTGGTTAGTCCAA
AGAGGAATCAAAACACTTGCACTCCGGATGGAGGCCCATTCAGCAAATGCTCAAAAAATTGCTGAGTTTTTAGAAGCATC
ACAAGCTGTTTCAAAAGTCTATTATCCAGGTCTCGTCAATCATGAAGGACATGAGATTGCTAAAAAACAAATGACTGCTT
TTGGTGGAATGATTTCATTTGAATTGACTGACGAAAATGCGGTTAAAAATTTTGTTGAAAACTTGCGCTATTTTACACTA
GCCGAATCACTCGGCGGAGTCGAATCTTTGATTGAAGTGCCAGCAGTAATGACTCATGCCTCAATTCCTAAAGAACTTCG
GGAAGAAATTGGGATAAAAGATGGATTGATTCGCTTATCAGTCGGTGTTGAAGCTCTTGAAGATTTACTGACGGACCTTA
AAGAAGCACTCGAAAAAGAATAA

Protein sequence :
MTSLKTKVIHGGISTDRTTGAVSVPIYQTSTYKQNGLGQPKEYEYSRSGNPTRHALEELIADLEGGVQGFAFSSGLAGIH
AVLSLFSTGDHIILADDVYGGTFRLMDKVLTKTGIIYDLVDLSNLEDLKAAFKAETKAVYFETPSNPLLKVLDIKEISSI
AKAHNALTLVDNTFATPYLQQPIALGADIVLHSATKYLGGHSDVVAGLVTTNSNELASEIGFLQNSIGAVLGPQDSWLVQ
RGIKTLALRMEAHSANAQKIAEFLEASQAVSKVYYPGLVNHEGHEIAKKQMTAFGGMISFELTDENAVKNFVENLRYFTL
AESLGGVESLIEVPAVMTHASIPKELREEIGIKDGLIRLSVGVEALEDLLTDLKEALEKE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-96 55
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 6e-98 55
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 5e-73 44

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
metC YP_006999213.1 cystathionine gamma-synthase/cystathionine beta-lyase BAC0207 Protein 8e-71 43