Gene Information

Name : cadA (BN424_2368)
Accession : YP_006993123.2
Strain : Carnobacterium maltaromaticum LMA28
Genome accession: NC_019425
Putative virulence/resistance : Resistance
Product : cadmium-translocating P-type ATPase
Function : -
COG functional category : -
COG ID : -
EC number : 3.6.3.3
Position : 2373109 - 2375244 bp
Length : 2136 bp
Strand : +
Note : [P] COG2217 Cation transport ATPase

DNA sequence :
ATGGCAGAAAAGACTGTTTATAGAGTAGATGGATTGAGCTGTACAAATTGCGCGGCCAAATTTGAACGGAACGTAAAAGA
AATTGAGGGTGTAACAGAAGCTATTGTAAACTTTGGCGCATCAAAAATCACGGTAACAGGTGAAGCAAGTATTCAACAAG
TTGAACAGGCTGGAGCATTTGAACACTTGAAAATCATTCCAGAGAAAGCATCCTTTACTGATCCAGAGCATTTTACTGAC
CATCAATCGTTTATTAGAAAAAATTGGCGATTATTGCTTTCTGGCTTATTTATTGCAGTGGGTTATGCGTCACAGATCAT
GAATGGGGAGGACTTTTATCTTACTAAGGCACTATTTATTTTTGCGATTTTCATAGGAGGCTATTCTCTCTTTAAGGAAG
GATTCAAAAATTTATTGAAGTTTGAATTTACAATGGAGACACTGATGACAATAGCTATTATTGGAGCTGCTTTCATTGGT
GAATGGGCAGAAGGATCTATTGTGGTGATTCTATTCGCAGTAAGCGAGGCACTTGAACGTTACTCGATGGATAAGGCACG
ACAATCTATTCGTTCCCTAATGGACATTGCGCCAAAAGAGGCACTTGTGAGACGCTCGGGCACCGACAGAATGGTTCATG
TAGATGACATTCAAATTGGCGACATTATGATTATAAAGCCTGGTCAAAAAATTGCGATGGATGGTCACGTTGTGAAAGGT
TATTCAGCCGTCAATCAAGCAGCGATTACTGGTGAATCTATCCCTGTTGAAAAAAACATCGATGATTCCGTTTTTGCTGG
AACGTTAAATGAAGAAGGATTGCTTGAAGTTGCGGTCACAAAACGAGTAGAAGATACCACGATTTCAAAAATTATTCACT
TAGTTGAGGAGGCACAAGGTGAACGTGCTCCAGCTCAAGCCTTTGTTGATACATTTGCTAAATATTATACGCCAGCCATT
ATTGTGATCGCCGCACTGATTGCAACAGTACCGCCATTGCTGTTTGGCGGCAACTGGGAAACGTGGGTGTATCAAGGGTT
ATCTGTATTAGTGGTTGGGTGTCCTTGCGCCTTAGTTGTTTCAACTCCTGTTGCCATCGTCACCTCCATTGGAAATGCAG
CTAAAAATGGCGTATTGGTAAAAGGTGGCGTGTATTTAGAAGAAATTGGTGGGCTAAAAGCCATTGCGTTCGATAAAACT
GGTACCTTGACAAAAGGTGTGCCGGTGGTCACTGATTATATTGAACTAACAGAAGCCACAAACATTCAACAAAATAAAAA
CTATACCATCATGGCAGCACTGGAACAATTATCTCAACACCCCCTTGCTTCAGCCATTATTAAGTATGGAGAAACGAGAG
AAATGGATTTAACTAGTATTAATGTGAACGATTTTACATCCATCACAGGAAAAGGGATTAGAGGAACTGTAGATGGTAAC
ACCTATTATGTTGGAAGTCCCGTTTTATTTAAGGAATTACTAACATCGCAATTTACTGACTCCATTCATCGACAAGTGAG
TGACTTACAACTTAAAGGGAAGACTGCTATGCTTTTTGGAACAAATCAGAACCTGATTTCTATAGTGGCAGTTGCCGACG
AGGTTAGGTCATCCAGTCAACATGTTATTAAACGACTTCATGAGCTGGGGATTGAAAAAACTATTATGTTGACTGGCGAT
AACCAAGCCACAGCGCAAGCAATTGGCCAACAGGTAGGTGTTTCTGAAATAGAAGGTGAGTTAATGCCCCAAGATAAATT
AGATTACATTAAACAGTTGAAAATAAACTTTGGTAAAGTAGCCATGGTTGGAGACGGTATTAATGATGCGCCAGCCTTAG
CAGCGGCCACGGTTGGAATTGCAATGGGCGGAGCAGGAACTGACACAGCCATTGAAACAGCTGATGTTGCCTTAATGGGA
GACGACTTACAAAAATTACCTTTCACGGTAAAGTTGAGTAGAAAAACACTCCAAATTATTAAGCAAAATATCACATTTTC
CTTGGTCATCAAACTGATTGCTCTTTTGCTAGTCATTCCAGGGTGGTTAACATTATGGATTGCAATTATGGCGGATATGG
GTGCGACTCTTTTAGTCACGTTAAATGGCTTACGATTAATGAAAGTGAAAGATTAA

Protein sequence :
MAEKTVYRVDGLSCTNCAAKFERNVKEIEGVTEAIVNFGASKITVTGEASIQQVEQAGAFEHLKIIPEKASFTDPEHFTD
HQSFIRKNWRLLLSGLFIAVGYASQIMNGEDFYLTKALFIFAIFIGGYSLFKEGFKNLLKFEFTMETLMTIAIIGAAFIG
EWAEGSIVVILFAVSEALERYSMDKARQSIRSLMDIAPKEALVRRSGTDRMVHVDDIQIGDIMIIKPGQKIAMDGHVVKG
YSAVNQAAITGESIPVEKNIDDSVFAGTLNEEGLLEVAVTKRVEDTTISKIIHLVEEAQGERAPAQAFVDTFAKYYTPAI
IVIAALIATVPPLLFGGNWETWVYQGLSVLVVGCPCALVVSTPVAIVTSIGNAAKNGVLVKGGVYLEEIGGLKAIAFDKT
GTLTKGVPVVTDYIELTEATNIQQNKNYTIMAALEQLSQHPLASAIIKYGETREMDLTSINVNDFTSITGKGIRGTVDGN
TYYVGSPVLFKELLTSQFTDSIHRQVSDLQLKGKTAMLFGTNQNLISIVAVADEVRSSSQHVIKRLHELGIEKTIMLTGD
NQATAQAIGQQVGVSEIEGELMPQDKLDYIKQLKINFGKVAMVGDGINDAPALAAATVGIAMGGAGTDTAIETADVALMG
DDLQKLPFTVKLSRKTLQIIKQNITFSLVIKLIALLLVIPGWLTLWIAIMADMGATLLVTLNGLRLMKVKD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 0.0 69
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 0.0 68
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 0.0 68

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
cadA YP_006993123.2 cadmium-translocating P-type ATPase BAC0298 Protein 1e-121 47
cadA YP_006993123.2 cadmium-translocating P-type ATPase BAC0092 Protein 3e-100 41