Gene Information

Name : Theos_0686 (Theos_0686)
Accession : YP_006971845.1
Strain : Thermus oshimai JL-2
Genome accession: NC_019386
Putative virulence/resistance : Virulence
Product : ATP-dependent chaperone ClpB
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 630683 - 633247 bp
Length : 2565 bp
Strand : +
Note : PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; Clp amino terminal domain; ATPase family associated with various cellular activities (AAA); TIGRFAM: ATP-dependent chaperone ClpB

DNA sequence :
ATGAACCTGGAACGCTGGACCCAAGCCGCGCGGGAAGCCCTGGCCCAGGCCCAGGTCCTGGCCCGGAGCATGAAGCACCA
GGCCCTGGACCGGGCCCACCTCTGGGCCGTGCTCCTTAAAGATCCCACGGGCCTCCCCGCGCGGCTTCTCGCCAAGGCCG
GGGTGGAGGCGGCCGCGGTGCGCAAGGAGGCGGAGGCCGCCCTGGCCCGCCTCCCCCGGGTGGAGGGGGCCGAAGGGGGG
CAGTACTTGACCCGCGAGCTCGCCGCCACCCTGGACCGGGCGGAGGCCCTCATGGGGGAGCTCGGGGACCGCTTCGTGGC
CCTGGACACCCTGGTCCTGGCCTTGGCGGAATCCACCCCAGGCCTCCCGCCCCTGGAGGCCCTTAAGGCCGCGCTTAAAG
AACTTAGAGGAGGTAAGACCGTGCAGACGGAACACGCGGAGGGCACCTACAACGCCTTAGAGCAGTACGGCATTGACCTG
ACCAGGATGGCCGCGGAGGGGAAGCTGGACCCGGTGATCGGCCGGGACGAGGAGATCCGCCGGGTGATCCAGATCCTCCT
CAGGCGCACCAAGAACAACCCCGTGCTCATCGGCGAGCCGGGGGTGGGGAAGACGGCCATCGTGGAGGGCCTGGCCCAGC
GCATCGTCAAGGGGGATGTGCCCGAGGGGCTGAAGGGGAAGCGCATCATCTCCCTGCAGATGGGCTCCCTCCTCGCCGGG
GCCAAGTACCGCGGCGAGTTTGAGGAGCGCCTGAAGGCGGTGATCCAGGAGGTGGTGGGGAGCCAAGGGGAGATCATCCT
CTTCATCGACGAGCTCCACACCGTGGTGGGGGCGGGCAAGGCGGAAGGGGCCGTGGACGCGGGCAACATGCTGAAGCCCG
CCCTGGCCCGGGGGGAGCTCAGGCTCATCGGGGCCACCACCTTGGACGAGTACCGGGAGATTGAGAAGGACCCGGCCCTA
GAGCGGCGCTTCCAGCCCGTCTATGTGGACGAGCCCAGCGTGGAGGAGACCATCTCCATCCTCCGGGGCCTTAAGGAGAA
GTACGAGGTCCACCACGGGGTGCGCATCTCGGATAGCGCCCTCATCGCCGCGGCCACCCTCTCCCACCGCTACATCACGG
AAAGGCGCCTGCCCGACAAGGCCATTGACCTCATTGACGAGGCCGCGGCCCGCCTGCGCATGGCCCTGGAAAGCGCCCCT
GAGGAAATAGATGCCCTGGAGCGCCGGAAGCTCCAGCTGGAGATCGAGCGGGAGGCCCTGAAGAAGGAGAAGGACCCCGA
GGCCCAGACCCGCCTTAAGGCCATAGAGGAGGAGATCGGGAAGCTTGCCCAGGAGATCGCCACCCTCCGGGCGGAGTGGG
AGAAGGAGCGGGAGGTCCTAAGGCGCCTCCGCGAGGCCCAGCAGCGCCTGGACGAGGTGAGGCGGCAGATTGAGCTGGCG
GAAAGGCAGTACGACCTGAACCGGGCCGCCGAGCTCCGCTACGGGGAGCTGCCCAAGCTCGAGGCCGAGGTGGAGGCCTT
AAGCCAGGAGCTCAAGGGGGCCCGCTTCGTGCGCCTGGAGGTCACGGAGGAGGACATCGCCGAGATCGTCTCCCGTTGGA
CGGGCATCCCCGTGTCCCGCCTCCTGGAGGGGGAAAGGGAAAAGCTCTTGAGGCTTGAGGACGAGCTCCACAAGCGGGTG
GTGGGGCAGGACGAGGCCATAAGGGCGGTGGCCGACGCCATCCGCCGGGCCCGGGCCGGCCTCAAGGACCCGAACCGCCC
CATCGGGAGCTTCCTCTTCCTGGGCCCCACGGGGGTGGGGAAGACGGAGCTGGCCAAGACCCTGGCGGCCACCCTCTTTG
ACACCGAGGAGGCCATGGTGCGCATTGACATGACGGAGTACATGGAAAAGCACGCGGTCTCCCGGCTCATCGGGGCCCCG
CCCGGGTACGTGGGCTACGAGGAGGGCGGCCAGCTCACGGAGGCCGTGCGCCGCAGGCCCTACACCGTCATCCTCTTTGA
CGAGATTGAAAAGGCCCACCCCGATGTCTTCAACCTCCTCCTGCAGATCCTGGACGACGGCCGCCTCACGGACAGCCACG
GGCGCACGGTGGACTTCCGCAACACGGTCATCATCCTCACCTCCAACCTGGGTAGCCCACTGATCCTGGAAGGGCTCCAG
CAGGGTCTCCCCTACGAGGCCATCCGGGATCGGGTCTTCCGCGAGCTCCAGCGCCACTTCCGCCCCGAGTTCCTGAACCG
TTTGGACGAGATCGTCCTCTTCCGGCCCCTCAGCAAGGAGCAAATCCGGCAGATCGTGGAGATCCAGCTGGCCAACCTGC
GGGCGCGCCTAGGGGAGCGCCGCATCAGCTTGGAGCTCACGGAGGCCGCCAAGGACTTCCTGGCGGAGCGGGGCTACGAC
CCGGTCTTCGGGGCGAGGCCCCTCAAGCGGGTCATCCAGCGGGCGCTGGAAACGCCCTTAGCGGAAAAGATCCTCTCCGG
GGAGATCAAAGACGGGGACAAGGTGGTGGTGGAGGCCACGCCCCAGGGCCTGAGCTTCCAGGTGGTCGCCCGGATAGAGG
CCTAA

Protein sequence :
MNLERWTQAAREALAQAQVLARSMKHQALDRAHLWAVLLKDPTGLPARLLAKAGVEAAAVRKEAEAALARLPRVEGAEGG
QYLTRELAATLDRAEALMGELGDRFVALDTLVLALAESTPGLPPLEALKAALKELRGGKTVQTEHAEGTYNALEQYGIDL
TRMAAEGKLDPVIGRDEEIRRVIQILLRRTKNNPVLIGEPGVGKTAIVEGLAQRIVKGDVPEGLKGKRIISLQMGSLLAG
AKYRGEFEERLKAVIQEVVGSQGEIILFIDELHTVVGAGKAEGAVDAGNMLKPALARGELRLIGATTLDEYREIEKDPAL
ERRFQPVYVDEPSVEETISILRGLKEKYEVHHGVRISDSALIAAATLSHRYITERRLPDKAIDLIDEAAARLRMALESAP
EEIDALERRKLQLEIEREALKKEKDPEAQTRLKAIEEEIGKLAQEIATLRAEWEKEREVLRRLREAQQRLDEVRRQIELA
ERQYDLNRAAELRYGELPKLEAEVEALSQELKGARFVRLEVTEEDIAEIVSRWTGIPVSRLLEGEREKLLRLEDELHKRV
VGQDEAIRAVADAIRRARAGLKDPNRPIGSFLFLGPTGVGKTELAKTLAATLFDTEEAMVRIDMTEYMEKHAVSRLIGAP
PGYVGYEEGGQLTEAVRRRPYTVILFDEIEKAHPDVFNLLLQILDDGRLTDSHGRTVDFRNTVIILTSNLGSPLILEGLQ
QGLPYEAIRDRVFRELQRHFRPEFLNRLDEIVLFRPLSKEQIRQIVEIQLANLRARLGERRISLELTEAAKDFLAERGYD
PVFGARPLKRVIQRALETPLAEKILSGEIKDGDKVVVEATPQGLSFQVVARIEA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 8e-99 45
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 3e-98 43
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 2e-98 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Theos_0686 YP_006971845.1 ATP-dependent chaperone ClpB VFG2076 Protein 8e-109 44
Theos_0686 YP_006971845.1 ATP-dependent chaperone ClpB VFG2084 Protein 5e-97 43