Gene Information

Name : Theos_0004 (Theos_0004)
Accession : YP_006971189.1
Strain : Thermus oshimai JL-2
Genome accession: NC_019386
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 4054 - 5478 bp
Length : 1425 bp
Strand : +
Note : PFAM: Pyruvate kinase, barrel domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase

DNA sequence : 
ATGGGGCCTTTTAAGCGCACCAAGATCGTGGCCACCCTGGGCCCGGCCACCTCCACGGAGGAGGCCATCCGGGCCCTGGC
CGAGGCGGGGGCCGACGTGTTCCGCCTGAACTTCAGCCACGGCACCCCCGAGGACCACCGGGCCCGGGCCGCCTTGGTGC
GGGAGGTGGCCAGGGCCCTGGGCCGGCCCCTGGCCCTCCTTCAGGACCTCCAGGGGCCCAAGATCCGGGTGGGGCGCTTC
AGGGGAGGGCGGGTGGAGCTTAAGCCGGGGCAGCGCTTCCTCCTCACCGCCGAGCCCCGGGAGGGGGACGAGGAGGGGGT
TTCCGTGAGCTACAAGGGCCTCCCCGAGGACGTGCGCCCGGGGCAGGTCCTCCTCCTAGACGACGGCCGGATTCGCCTGA
GGGTGGAAGCGGTTCAAGGGCCGGAGATCCACACCCAGGTGGAGGTGGGGGGGGTCCTCTCCGACCACAAGGGCATCAAC
ATCCCCGGCTCCGACCTCTCCATCCCCGCCCTTTCGGAAAAGGACATCCAGGACCTGGCCCTGGGGGCGGAGATCGGGGT
GGACTGGGTGGCGGTCTCCTTCGTGCGCACCCGGGACGACCTCCTCCTGGCCCGCCACTACCTGGCCCGCTACGGCTCCC
CCGCCAAGCTCATGGCCAAGGTTGAGAAGCCCTCCGCCGTGGCCCGCTTTGAGGAGATCCTGGAGGAGGCCGACGGGATC
ATGGTGGCCCGGGGGGACCTGGGGGTGGAGATGCCCCTGGAGGAGGTCCCCATCGTGCAAAAGCGCCTCATCCTGCGGGC
CATCGCCGCGGGGAAGCCGGTGATCACCGCCACCCAGATGCTGGAGTCCATGGTGGCGAACCCCAGCCCCACCCGGGCCG
AGGCCTCGGACGTGGCCAACGCCATCTTTGACGGCACGGACGCGGTGATGCTCTCCGCGGAAACCGCCACGGGGGCCTAC
CCGGTGGAGGCGGTGGCCATGATGGCCCGCATCGCCCGGGCGGTGGAGGCTTCCCCGGAGTTCCTCCAGAAGCTCAACGT
CCTAAGGCCCCACCCCACCCCCACCACCCAGGACGCCATCGCCCAGGCGGCGGACGACGTGGTGGAGGCGGTGGGGGCCC
GGGCCATCGTGGTCTTCACCGCCACGGGGAGCTCCGCCCGCCGCATCGCCCGCACCCGGCCCCAGGTGCCCATCCTGGCC
CTCACCCCGAACCCCGAGGTGGTCCACCAGCTGGCCCTGGTCTGGGGGGTCTGCCCCAGGCTGGCCCCCGACCCCAAGGA
CACGGACGATATGGTCCGGATTGCCCTAAGGGCGGTGAAGGAGGAAGGGCTGGCCCAGATCGGGGACCGGGTGGTCATCG
CCGCGGGGGTGCCCTTCGGGGTGCGGGGAACCACCAACCTCCTCCGGGTGGAGCGGGTGGGTTAA

Protein sequence : 
MGPFKRTKIVATLGPATSTEEAIRALAEAGADVFRLNFSHGTPEDHRARAALVREVARALGRPLALLQDLQGPKIRVGRF
RGGRVELKPGQRFLLTAEPREGDEEGVSVSYKGLPEDVRPGQVLLLDDGRIRLRVEAVQGPEIHTQVEVGGVLSDHKGIN
IPGSDLSIPALSEKDIQDLALGAEIGVDWVAVSFVRTRDDLLLARHYLARYGSPAKLMAKVEKPSAVARFEEILEEADGI
MVARGDLGVEMPLEEVPIVQKRLILRAIAAGKPVITATQMLESMVANPSPTRAEASDVANAIFDGTDAVMLSAETATGAY
PVEAVAMMARIARAVEASPEFLQKLNVLRPHPTPTTQDAIAQAADDVVEAVGARAIVVFTATGSSARRIARTRPQVPILA
LTPNPEVVHQLALVWGVCPRLAPDPKDTDDMVRIALRAVKEEGLAQIGDRVVIAAGVPFGVRGTTNLLRVERVG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 1e-68 45
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 1e-68 45
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 1e-68 45
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 2e-68 45
pykA NP_273151.1 pyruvate kinase Not tested IHT-A Protein 6e-62 45

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Theos_0004 YP_006971189.1 pyruvate kinase VFG0479 Protein 5e-69 45