Gene Information

Name : Theos_1541 (Theos_1541)
Accession : YP_006972666.1
Strain : Thermus oshimai JL-2
Genome accession: NC_019386
Putative virulence/resistance : Virulence
Product : NAD-dependent aldehyde dehydrogenase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1493771 - 1495249 bp
Length : 1479 bp
Strand : +
Note : PFAM: Aldehyde dehydrogenase family; manually curated

DNA sequence :
GTGCTTCCCCTACCCCCAAAGGCTCAGGTCTTCCTGCAGCGAGTGGGACCACTCTACCTGGGCGGCCGCTTCCAGGAAGC
GGCGAGCGGAGCTCGCTTTCCCGTCCTCAACCCGGCCACAGGGGAAGTCCTAGCCCAGGTGGCCCGCGGTGGACCTGAGG
ACGTGGACCGGGCGGTGGCCCTGGCCCGCAAGGCCCTGGAGGGAAGCTGGGGCCGTACCACCCCAGACGAACGGGGGCGG
CTCCTTTATCGTCTCAGCGAACTCATTGAAGCCCACGCGGACGCGCTAGCAGCCCTCGAAGCCCTTAACGTGGGCAAGCC
CTACACCGAGGCCCGCACGGCAGACATCCCCCTAGCCGCCCAGCACTTCCGCTACTTCGCCGGTTGGACCACCAAATGGA
GCGGGGAGGTCCTCCCTGTATCCTTCCCAGGGGAGCACCTAGCCTACACCCGCCGGGAGCCCGTAGGGGTGGTAGGGGCC
ATCACCCCCTGGAACTTTCCGCTCCTTATCGCCAGCTGGAAACTGGCCCCAGCCTTGGCTGCGGGGTGCGCAGTGGTCCT
CAAACCCTCCGAACTCACCCCCCTCACGGCCCTCTACTTGGCCGAGCTGGTGGAGGAGGCGGGCTTTCCTAAGGGGACGG
TAAGCGTCATCCCGGGGTTGGGGGAGGAAGCAGGGGCAGCCCTGGTGGCTCATCCGGGGGTGGACAAGATTTCCTTCACC
GGCTCCGTGGAGGTGGGGAAAGCCATCCTGAAGAAGGCCGTAGACAGCCTCAAGCGGGTCACCTTGGAGCTTGGGGGCAA
GTCCCCCAATATCCTCCTAGAGGATGCAGACCCCAAACGGGTCCTCAAGGGGGTGCTCTTCGCAAGCTTCTTTAACCAAG
GAGAGGTCTGCGCCGCGGGGAGCCGCCTCTTCGTGCCTAAGGCCAAGTTGGACGCCACGCTGGAGCTTCTGGTGGAGGAA
GCAAGGCGGATCCGCCAAGGCCACCCCCTGGACCCGAGGACCCAGATGGGCCCCCTGGTGAGCAAGGAGCACATGGAGCG
AGTTCTGGGCTACATTGAAAAGGGCAAGGAGGAGGGTGCAGAACTCCTCTTAGGTGGGGAGCGCAATCCCGAAGCAGGAC
CAGGGTTCTTCGTTCAGCCCACCCTTTTCCTAGCCGAGGACCAGCATACCATTGCCCGGGAAGAGATCTTCGGCCCGGTG
CTCACCGTCCTCCCTTACGAGGATCTGGAGGAGGCGGTGCGCCGGGCTAACGCCACCCGCTACGGCCTCGCCGCCGGGGT
CTGGGGGCAGGACCTCCGCCGAGCCCTCAAGGTGGCCCACCGGCTCCAGGCAGGGACGGTGTGGGTGAACGGCTACCTCC
TTCTGGACGCCACCAGCCCCTGGGGGGGGTACAAAGAAAGCGGGCTCGGGCGAGAAATGGGGCGCTACGCCCTGGAACAC
TACACGGAAGTGAAAAGCGTCTGGGTCAACCTAGGCTAA

Protein sequence :
MLPLPPKAQVFLQRVGPLYLGGRFQEAASGARFPVLNPATGEVLAQVARGGPEDVDRAVALARKALEGSWGRTTPDERGR
LLYRLSELIEAHADALAALEALNVGKPYTEARTADIPLAAQHFRYFAGWTTKWSGEVLPVSFPGEHLAYTRREPVGVVGA
ITPWNFPLLIASWKLAPALAAGCAVVLKPSELTPLTALYLAELVEEAGFPKGTVSVIPGLGEEAGAALVAHPGVDKISFT
GSVEVGKAILKKAVDSLKRVTLELGGKSPNILLEDADPKRVLKGVLFASFFNQGEVCAAGSRLFVPKAKLDATLELLVEE
ARRIRQGHPLDPRTQMGPLVSKEHMERVLGYIEKGKEEGAELLLGGERNPEAGPGFFVQPTLFLAEDQHTIAREEIFGPV
LTVLPYEDLEEAVRRANATRYGLAAGVWGQDLRRALKVAHRLQAGTVWVNGYLLLDATSPWGGYKESGLGREMGRYALEH
YTEVKSVWVNLG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 3e-79 46
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 8e-74 46
hpaE AAO17179.1 HpaE Not tested tcd island Protein 1e-68 45
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 1e-80 44
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 1e-80 44
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 1e-80 44
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 3e-80 44
unnamed AAK01506.1 putative aldehyde dehydrogenase Not tested PAGI-1 Protein 2e-76 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Theos_1541 YP_006972666.1 NAD-dependent aldehyde dehydrogenase VFG0082 Protein 1e-79 46