Gene Information

Name : bscN (BN112_1828)
Accession : YP_006967892.1
Strain : Bordetella bronchiseptica 253
Genome accession: NC_019382
Putative virulence/resistance : Virulence
Product : ATP synthase in type III secretion system
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1986647 - 1987981 bp
Length : 1335 bp
Strand : -
Note : -

DNA sequence :
ATGCGTCAGTACCACTACATCACGGAGATGATGCGGGTGGCCCTGCAGGATCTGTCCACGTTGCGGATAAAGGGCCGAGT
GGTGCAAGTGGTGGGAACGATCATCAAGGCCGTCGTTCCGATGGTCAAGATCGGCGAAGTGTGCCTGCTGCGCAATCCTG
GCGAGGACTTCGAGATGCACGGCGAAGTGGTGGGCTTTGTTCGCGACGCCGCCTTGCTCACGCCCATCGGCGACATGTAC
GGGATTTCCTCGGCGACCGAGGTGATACCGACTGGACGCACGCATATGGTGCCCGTCGGTCCGGGCTTGCTGGGACGCGT
GCTGGACGGGCTGGGACGTCCGCTGGACGCCGCCGAGTCAGGGCCGCTGCATGCCCACAAGTTCTATCCGGTTTTCGCCG
ATGCGCCGGATCCGCTGACGCGTCGCATCATCCATGCTCCGCTGGAGCTGGGGGTGCGCGTACTGGACGGTTTGCTTACA
TGCGGGGAAGGCCAGCGTCTGGGAATTTTCGCAGCAGCCGGCGGCGGCAAGTCGACCTTGCTGGGCATGCTGGTCAAGGG
CGCCGCGGTCGACGTGACGGTGGTGGCGCTGATCGGCGAGCGTGGGCGGGAAGTTCGCGAGTTCCTTGAGCACGAACTCG
GTCCGGAGGGCAGGCGCAAGAGCGTGATCGTCTGCGCGACCAGCGACAAGTCCTCGATGGAGCGTGCCAAGGCGGCGTAC
GTCGCAACCGCCATCGCCGAATACTTCCGCGATCAAGGGCAGCGTGTACTTTTTCTGATGGACTCGGTCACCCGCTTTGC
GCGAGCCCAGCGTGAAATCGGCTTGGCGGCAGGCGAGCCGCCGACGCGGCGCGGCTATCCGCCGTCGGTGTTCGCCACCC
TGCCCAAACTGATGGAGCGCGCCGGCATGAACCAGACGGGTTCGATCACGGCGCTGTATACGGTGCTGGTCGAGGGGGAC
GACATGAACGAACCGGTGGCCGACGAGACGCGTTCGATACTGGACGGCCACATCGTGCTCTCGCGCAAGCTGGGAGCGGC
GAATCACTATCCTGCCGTCGACGTGCTGGCCTCAGCCAGCCGGGTCATGAATGCCGTGGTGTCGCCACGTCACAAGTACC
TGGCCGGACGTATGCGCGAACTGATGGCCAAGTACCAGGACGTCGAGCTGTTAGTGAAAATCGGCGAGTACAAGCAGGGC
GCCGATGCGTCGACCGATGAGGCGATACAGAAGATCGGACAGATCAATGCGTTTCTCAGACAACAAACCGACGAACGCGA
AGCATTCGAGGATACCGTACTGCGCATGGCTGAAATCATCGGACCCGAATCCTAA

Protein sequence :
MRQYHYITEMMRVALQDLSTLRIKGRVVQVVGTIIKAVVPMVKIGEVCLLRNPGEDFEMHGEVVGFVRDAALLTPIGDMY
GISSATEVIPTGRTHMVPVGPGLLGRVLDGLGRPLDAAESGPLHAHKFYPVFADAPDPLTRRIIHAPLELGVRVLDGLLT
CGEGQRLGIFAAAGGGKSTLLGMLVKGAAVDVTVVALIGERGREVREFLEHELGPEGRRKSVIVCATSDKSSMERAKAAY
VATAIAEYFRDQGQRVLFLMDSVTRFARAQREIGLAAGEPPTRRGYPPSVFATLPKLMERAGMNQTGSITALYTVLVEGD
DMNEPVADETRSILDGHIVLSRKLGAANHYPAVDVLASASRVMNAVVSPRHKYLAGRMRELMAKYQDVELLVKIGEYKQG
ADASTDEAIQKIGQINAFLRQQTDEREAFEDTVLRMAEIIGPES

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lscN AAO18044.1 LscN Virulence TTSS locus Protein 4e-128 62
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 4e-109 57
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 6e-109 57
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 7e-110 56
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 7e-110 56
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 9e-110 56
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 1e-109 56
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-108 56
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 8e-108 55
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 8e-108 55
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 4e-86 53
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 2e-86 53
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 3e-86 53
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 1e-86 53
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 1e-86 53
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 4e-88 53
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 2e-77 52
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 7e-84 52
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 7e-84 52
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 2e-80 51
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 7e-92 51
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 2e-83 51
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 2e-88 50
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 6e-84 50
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 1e-88 49
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 1e-88 49
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 4e-83 49
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 3e-83 49
escN AAC38383.1 EscN Virulence LEE Protein 7e-85 47
escN NP_290268.1 hypothetical protein Virulence LEE Protein 5e-85 47
escN AAC31513.1 L0034 Virulence LEE Protein 3e-85 47
ECs4568 NP_312595.1 EscN Virulence LEE Protein 5e-85 47
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 3e-85 47
escN CAC81862.1 EscN protein Virulence LEE II Protein 1e-84 47
escN AAK26715.1 EscN Virulence LEE Protein 8e-85 47
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 1e-84 47
escN AAL57542.1 EscN Virulence LEE Protein 8e-85 47
escN YP_003236088.1 translocator EscN Virulence LEE Protein 8e-85 47
invC AAS66861.1 InvC Not tested SSR-2 Protein 1e-80 46
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 3e-73 44
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 2e-76 43
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 2e-76 43
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 2e-76 43
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 2e-76 43
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 9e-73 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
bscN YP_006967892.1 ATP synthase in type III secretion system VFG0048 Protein 0.0 99
bscN YP_006967892.1 ATP synthase in type III secretion system VFG0192 Protein 7e-130 68
bscN YP_006967892.1 ATP synthase in type III secretion system VFG0390 Protein 1e-130 65
bscN YP_006967892.1 ATP synthase in type III secretion system VFG2144 Protein 2e-105 55
bscN YP_006967892.1 ATP synthase in type III secretion system VFG0515 Protein 1e-86 53
bscN YP_006967892.1 ATP synthase in type III secretion system VFG0812 Protein 2e-85 47
bscN YP_006967892.1 ATP synthase in type III secretion system VFG0730 Protein 4e-85 47
bscN YP_006967892.1 ATP synthase in type III secretion system VFG2459 Protein 5e-83 45
bscN YP_006967892.1 ATP synthase in type III secretion system VFG2331 Protein 8e-72 45
bscN YP_006967892.1 ATP synthase in type III secretion system VFG1254 Protein 1e-80 45
bscN YP_006967892.1 ATP synthase in type III secretion system VFG0555 Protein 9e-77 43
bscN YP_006967892.1 ATP synthase in type III secretion system VFG1008 Protein 4e-75 43
bscN YP_006967892.1 ATP synthase in type III secretion system VFG1778 Protein 7e-75 43
bscN YP_006967892.1 ATP synthase in type III secretion system VFG2499 Protein 2e-71 41