Gene Information

Name : guaA (C694_02085)
Accession : YP_006934335.1
Strain : Helicobacter pylori 26695
Genome accession: NC_018939
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : -
COG ID : -
EC number : 6.3.5.2
Position : 422138 - 423664 bp
Length : 1527 bp
Strand : +
Note : COG0518 GMP synthase - Glutamine amidotransferase domain

DNA sequence :
ATGATTTTAGTATTAGATTTTGGGAGTCAATACACACAGCTGATTGCTAGAAGATTGAGAGAGAGAGGGATTTATACAGA
AATAGTCCCTTTTTTTGAAAGCATAGAAAACATTCAAAAAAAAGCCCCCAAAGGTTTGATTTTGAGTGGGGGGCCAGCGA
GCGTGTATGCTAAAGACGCTTACAAGCCTAGTGGGAAAATCTTTGATTTGAATGTGCCGATTTTAGGGATTTGCTACGGC
ATGCAGTATTTGGTGGATTTTTTTGGGGGGGTAGTGGTTGGTGCGAATGAGCAAGAATTTGGTAAGGCTGTTTTAGAAAT
CACTCAAAATTCTGTGATTTTTGAAGGCGTGAAGATTAAAAGCCTTGTGTGGATGAGCCATATGGATAAAGTCATAGAAC
TGCCTAAAGGCTTTACTACCCTTGCAAAAAGCCCTAATTCCCCCCATTGCGCGATTGAAAACGGCAAGATTTTTGGCTTG
CAATTCCACCCAGAAGTCGTTCAAAGCGAAGAAGGGGGTAAGATTTTAGAAAATTTTGCCCTTTTAGTTTGCGGCTGTGA
AAAAACTTGGGGGATGCAGCATTTCGCTCAAAGAGAAATCGCACGATTGAAAGAAAAAATCGCTAACGCTAAGGTTTTGT
GCGCGGTGAGTGGGGGCGTGGATTCTACGGTGGTCGCTACGCTGTTGCACAGAGCCATTAAGGATAATTTGATCGCTGTT
TTTGTGGATCATGGCTTGTTGCGTAAAAATGAAAAAGAAAGGGTGCAAGCGATGTTTAAGGACTTGAAAATCCCTTTAAA
CACGATAGACGCTAAAGAAGTCTTTTTGTCTAAATTAAAGGGCGTGAGCGAGCCTGAATTGAAGCGAAAAATCATCGGCG
AGACCTTTATTGAAGTGTTTGAAAAAGAAGCCAAAAAGCACCATTTAAAAGGCAAAATTGAATTTTTAGCCCAAGGCACT
TTATACCCTGATGTGATTGAATCCGTGAGCGTTAAAGGGCCTTCAAAAGTGATCAAAACCCATCATAATGTGGGCGGACT
GCCTGAATGGATGGATTTTAAACTCATAGAGCCTTTAAGGGAGTTGTTTAAAGATGAGGTGCGCTTACTGGGTAAAGAAT
TGGGCGTTAGTCAGGATTTTTTAATGCGCCACCCTTTTCCAGGGCCTGGGCTTGCTGTAAGGATTTTAGGCGAAATCAGT
GAGAGTAAGATCAAACGCTTGCAAGAAGCGGATTTTATTTTTATAGAGGAACTTAAAAAAGCCAATTTGTATGACAAGGT
TTGGCAAGCTTTTTGCGTGCTGTTGAATGTCAATTCTGTGGGGGTTATGGGGGATAACCGCACTTATGAAAACGCTATTT
GCTTAAGAGCGGTAAATGCGAGCGATGGCATGACGGCGAGCTTTTCATTTTTAGAGCATTCTTTTTTAGAAAAGGTTTCT
AACCGTATCACTAATGAAGTGAGCGGTATCAATAGGGTGGTGTATGACATTACCTCTAAACCACCAGGAACGATTGAATG
GGAATGA

Protein sequence :
MILVLDFGSQYTQLIARRLRERGIYTEIVPFFESIENIQKKAPKGLILSGGPASVYAKDAYKPSGKIFDLNVPILGICYG
MQYLVDFFGGVVVGANEQEFGKAVLEITQNSVIFEGVKIKSLVWMSHMDKVIELPKGFTTLAKSPNSPHCAIENGKIFGL
QFHPEVVQSEEGGKILENFALLVCGCEKTWGMQHFAQREIARLKEKIANAKVLCAVSGGVDSTVVATLLHRAIKDNLIAV
FVDHGLLRKNEKERVQAMFKDLKIPLNTIDAKEVFLSKLKGVSEPELKRKIIGETFIEVFEKEAKKHHLKGKIEFLAQGT
LYPDVIESVSVKGPSKVIKTHHNVGGLPEWMDFKLIEPLRELFKDEVRLLGKELGVSQDFLMRHPFPGPGLAVRILGEIS
ESKIKRLQEADFIFIEELKKANLYDKVWQAFCVLLNVNSVGVMGDNRTYENAICLRAVNASDGMTASFSFLEHSFLEKVS
NRITNEVSGINRVVYDITSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 2e-133 53
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 2e-133 53
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 2e-133 53
guaA NP_938969.1 GMP synthase Not tested Not named Protein 4e-115 47