Gene Information

Name : C730_02825 (C730_02825)
Accession : YP_006936077.1
Strain : Helicobacter pylori Rif2
Genome accession: NC_018938
Putative virulence/resistance : Virulence
Product : cag pathogenicity island protein (cag26)
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 579930 - 583490 bp
Length : 3561 bp
Strand : +
Note : COG0419 ATPase involved in DNA repair

DNA sequence : 
ATGACTAACGAAACTATTGATCAAACAAGAACACCAGATCAAACACAAAGCCAAACAGCTTTTGATCCGCAACAATTTAT
CAATAATCTTCAAGTGGCTTTTATTAAAGTTGATAATGTTGTCGCTTCATTTGATCCTGATCAAAAACCAATCGTTGATA
AGAACGATAGGGATAACAGGCAAGCTTTTGATGGAATCTCGCAATTAAGGGAAGAATACTCCAATAAAGCGATCAAAAAT
CCTACCAAAAAGAATCAGTATTTTTCAGACTTTATCGATAAGAGCAATGATTTAATCAACAAAGACAATCTCATTGATGT
AGAATCTTCCACAAAGAGCTTTCAGAAATTTGGGGATCAGCGTTACCAAATTTTCACAAGTTGGGTGTCCCATCAAAAAG
ATCCGTCTAAAATCAACACCCGATCGATCCGAAATTTTATGGAAAATATCATACAACCCCCTATCCCTGATGATAAAGAA
AAAGCAGAGTTTTTGAAATCTGCCAAACAATCTTTTGCAGGAATCATTATAGGGAATCAAATCCGAACGGATCAAAAGTT
CATGGGCGTGTTTGATGAATCCTTGAAAGAAAGGCAAGAAGCAGAAAAAAATGGAGGGCCTACTGGTGGGGATTGGTTGG
ATATTTTTCTCTCATTTATATTTAACAAAAAACAATCTTCCGATGTCAAAGAAGCAATCAATCAAGAACCAGTTCCCCAT
GTCCAACCAGATATAGCCACTACTACCACCGACATACAAGGCTTACCGCCTGAAGCTAGGGATTTACTTGATGAAAGGGG
TAATTTTTCTAAATTCACTCTTGGCGATATGGAAATGTTAGATGTTGAGGGAGTCGCTGACATTGATCCTAATTACAAGT
TCAATCAATTATTGATTCACAATAACGCTCTGTCTTCTGTGTTAATGGGGAGTCATAATGGCATAGAACCTGAAAAAGTT
TCATTATTGTATGCGGGCAATGGTGGTTTTGGAGACAAACACGATTGGAACGCCACCGTTGGTTATAAAGACCAACAAGG
TAACAATGTGGCTACACTCATTAATGTGCATATGAAAAACGGCAGTGGCTTAGTCATAGCAGGTGGTGAGAAAGGGATTA
ATAACCCTAGTTTTTATCTCTACAAAGAAGACCAACTCACAGGCTCACAACGAGCATTGAGTCAAGAAGAGATCCGAAAC
AAAGTAGATTTCATGGAATTTCTTGCACAAAATAATACTAAATTAGACAACTTGAGCGAGAAAGAGAAAGAAAAATTCCA
AAATGAGATTGAAGATTTTCAAAAAGACTCTAAGGCTTATTTAGACGCCCTAGGGAATGATCGTATTGCTTTTGTTTCTA
AAAAAGACACAAAACATTCAGCTTTAATTACTGAGTTTAATAATGGGGATTTGAGCTACACTCTCAAAGATTATGGGAAA
AAAGCAGATAAAGCTTTAGATAGGGAGAAAAATGTTACTCTTCAAGGTAGCCTAAAACATGATGGCGTGATGTTTGTTGA
TTATTCTAATTTCAAATACACCAACGCCTCCAAGAATCCCAATAAGGGTGTAGGCGCTACGAATGGCGTTTCCCATTTAG
AAGCAGGCTTTAACAAGGTAGCTGTCTTTAATTTGCCTGATTTAAATAATCTCGCTATCACTAGTTTCGTAAGGCGGAAT
TTAGAGAATAAACTAACCGCTAAAGGATTGTCCCTACAAGAAGCTAATAAGCTCATCAAAGACTTTTTGAGCAGCAACAA
AGAATTGGCTGGAAAAGCTTTAAACTTCAATAAAGCTGTAGCTGAAGCTAAAAGCACAGGCAACTATGACGAGGTGAAAA
AAGCTCAGAAAGATCTTGAAAAATCCCTAAGGAAACGAGAGCATTTGGAGAAAGAAGTAGAGAAAAAATTGGAGAGCAAA
AGCGGCAACAAAAATAAAATGGAAGCAAAAGCTCAAGCTAACAGCCAAAAAGATGAGATTTTTGCGTTGATCAATAAAGA
GGCTAATAGGGATGCAAGAGCAATCGCTTACACTCAAAATCTTAAAGGCATCAAAAGGGAATTGTCTGATAAACTTGAAA
AAATCAGCAAGGATTTGAAAGACTTTAGTAAATCTTTTGATGAATTCAAAAATGGCAAAAATAAGGATTTCAGCAAGGCA
GAAGAAACGCTAAAAGCCCTTAAAGGCTCGGTGAAAGATTTAGGTATCAATCCAGAATGGATTTCAAAAGTTGAAAACCT
TAATGCAGCTTTGAATGAATTCAAAAATGGCAAAAATAAGGATTTCAGCAAGGTAACGCAAGCAAAAAGCGACCTTGAAA
ATTCCGTTAAAGATGTGATCATCAATCAAAAGGTAACGGATAAAGTTGACAATCTCAATCAAGCGGTATCAGTGGCTAAA
GCAATGGGCGATTTCAGTAGGGTAGAGCAAGTGTTAGCCGATCTCAAAAACTTCTCAAAGGAGCAATTGGCTCAACAAGC
TCAAAAAAATGAAGATTTCAATACTGGAAAAAATTCTGAACTATACCAATCCGTTAAGAATAGTGTAAATAAAACCCTAG
TCGGTAATGGGTTATCTGGAATAGAGGCCACAGCTCTCGCCAAAAATTTTTCGGATATCAAGAAAGAATTGAATGAGAAA
TTTAAAAATTTCAATAACAATAATAATGGACTCAAAAACAGCACAGAACCCATTTATGCTAAAGTTAATAAAAAGAAAAC
AGGACAAGTAGCTAGCCCTGAAGAACCCATTTATACTCAAGTTGCTAAAAAGGTAAATGCAAAAATTGACCGACTCAATC
AAATAGCAAGTGGTTTGGGTGGTGTAGGGCAAGCAGCGGGCTTCCCTTTGAAAAGGCATGATAAAGTTGATGATCTCAGT
AAGGTAGGGCTTTCAGCTAGCCCTGAACCCATTTACGCTACGATTGATGATCTCGGCGGACCTTTCCCTTTGAAAAGGCA
TGATAAAGTTGATGATCTCAGTAAGGTAGGGCGATCAAGGAATCAAGAATTGGCTCAGAAAATTGACAATCTCAATCAAG
CGGTATCAGAAGCTAAAGCAGGTTTTTTTGGCAACCTAGAGCAAACGATAGACAAGCTCAAAGATTCTACAAAAAAGAAT
GTTATGAATCTATATGTTGAAAGTGCAAAAAAAGTGCCTGCTAGTTTGTCAGCGAAATTGGACAATTATGCTATTAACAG
CCACACACGCATTAATAGCAATATCCAAAATGGAGCAATCAATGAAAAAGCGACCGGTATGCTAACGCAAAAAAACCCTG
AGTGGCTTAAGCTCGTGAATGATAAGATAGTTGCGCATAATGTGGGAAGCGTTTCTTTGTCAGAGTATGATAAAATTGGC
TTCAACCAGAAGAATATGAAAGATTATTCTGATTCGTTCAAGTTTTCCACCAAGTTGAACAATGCTGTAAAAGACATTAA
GTCTGGCTTTACGCACTTTTTAGCCAATGCATTTTCTACAGGATATTACTGCTTGGCGAGGGAAAATGCGGAGCATGGAA
TCAAAAATGTTAATACAAAAGGTGGTTTCCAAAAATCTTAA

Protein sequence : 
MTNETIDQTRTPDQTQSQTAFDPQQFINNLQVAFIKVDNVVASFDPDQKPIVDKNDRDNRQAFDGISQLREEYSNKAIKN
PTKKNQYFSDFIDKSNDLINKDNLIDVESSTKSFQKFGDQRYQIFTSWVSHQKDPSKINTRSIRNFMENIIQPPIPDDKE
KAEFLKSAKQSFAGIIIGNQIRTDQKFMGVFDESLKERQEAEKNGGPTGGDWLDIFLSFIFNKKQSSDVKEAINQEPVPH
VQPDIATTTTDIQGLPPEARDLLDERGNFSKFTLGDMEMLDVEGVADIDPNYKFNQLLIHNNALSSVLMGSHNGIEPEKV
SLLYAGNGGFGDKHDWNATVGYKDQQGNNVATLINVHMKNGSGLVIAGGEKGINNPSFYLYKEDQLTGSQRALSQEEIRN
KVDFMEFLAQNNTKLDNLSEKEKEKFQNEIEDFQKDSKAYLDALGNDRIAFVSKKDTKHSALITEFNNGDLSYTLKDYGK
KADKALDREKNVTLQGSLKHDGVMFVDYSNFKYTNASKNPNKGVGATNGVSHLEAGFNKVAVFNLPDLNNLAITSFVRRN
LENKLTAKGLSLQEANKLIKDFLSSNKELAGKALNFNKAVAEAKSTGNYDEVKKAQKDLEKSLRKREHLEKEVEKKLESK
SGNKNKMEAKAQANSQKDEIFALINKEANRDARAIAYTQNLKGIKRELSDKLEKISKDLKDFSKSFDEFKNGKNKDFSKA
EETLKALKGSVKDLGINPEWISKVENLNAALNEFKNGKNKDFSKVTQAKSDLENSVKDVIINQKVTDKVDNLNQAVSVAK
AMGDFSRVEQVLADLKNFSKEQLAQQAQKNEDFNTGKNSELYQSVKNSVNKTLVGNGLSGIEATALAKNFSDIKKELNEK
FKNFNNNNNGLKNSTEPIYAKVNKKKTGQVASPEEPIYTQVAKKVNAKIDRLNQIASGLGGVGQAAGFPLKRHDKVDDLS
KVGLSASPEPIYATIDDLGGPFPLKRHDKVDDLSKVGRSRNQELAQKIDNLNQAVSEAKAGFFGNLEQTIDKLKDSTKKN
VMNLYVESAKKVPASLSAKLDNYAINSHTRINSNIQNGAINEKATGMLTQKNPEWLKLVNDKIVAHNVGSVSLSEYDKIG
FNQKNMKDYSDSFKFSTKLNNAVKDIKSGFTHFLANAFSTGYYCLARENAEHGIKNVNTKGGFQKS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
HP0547 NP_207343.1 cag pathogenicity island protein (cag26) Virulence cag PAI Protein 0.0 100
cagA AAR03970.1 CagA Virulence cag PAI Protein 0.0 93
cagA AAR03881.1 CagA Virulence cag PAI Protein 0.0 92
cagA AAF17598.1 CagA Virulence cag PAI Protein 0.0 92
HP0547 BAD14045.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 91
cagA BAD51747.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 91
cagA AAR03909.1 CagA Virulence cag PAI Protein 0.0 90
cagA BAC10428.1 CagA Virulence cag PAI Protein 0.0 90
HP0547 BAD13908.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 90
cagA AAC44706.1 CagA Virulence cag PAI Protein 0.0 89
cagA BAD51750.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 86
cagA BAD51758.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 86
cagA BAD51760.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 86
cagA AGC69806.1 cag pathogenicity island protein A Virulence cag PAI Protein 0.0 86
cagA YP_003728762.1 cytotoxin-associated protein A Virulence cag PAI Protein 0.0 86
cagA BAD51761.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 86
cagA AAR03939.1 CagA Virulence cag PAI Protein 0.0 86
cagA NP_223213.1 cag island protein, cytotoxicity associated immunodominant antigen Virulence cag PAI Protein 0.0 85
cagA BAD51751.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 85
cagA BAD51756.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 85
cagA BAD51753.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 85
cagA BAD51766.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 85
cagA BAC10432.1 CagA Virulence cag PAI Protein 0.0 85
HP0547 BAD13990.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 85
cagA BAD51752.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 84
cagA BAD51764.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 83
cagA BAC10429.1 CagA Virulence cag PAI Protein 0.0 83
HP0547 BAD13935.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 83
cagA BAD51759.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 82
cagA BAD51754.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 79
cagA YP_005777288.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 79
cagA BAC10426.1 CagA Virulence cag PAI Protein 0.0 79
cagA BAC10421.1 CagA Virulence cag PAI Protein 0.0 79
HP0547 BAD13799.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 79
cagA BAC10433.1 CagA Virulence cag PAI Protein 0.0 79
HP0547 BAD14018.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 79
cagA YP_005779046.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 79
cagA BAD51755.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 79
cagA BAC10435.1 CagA Virulence cag PAI Protein 0.0 79
cagA BAC10431.1 CagA Virulence cag PAI Protein 0.0 79
HP0547 BAD14072.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 79
HP0547 BAD13963.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 79
cagA YP_005775747.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 79
cagA BAD51749.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 79
cagA BAC10419.1 CagA Virulence cag PAI Protein 0.0 79
cagA BAD51762.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 79
cagA BAC10420.1 CagA Virulence cag PAI Protein 0.0 78
cagA BAD51744.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 78
HP0547 BAD13880.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 78
cagA AAF17597.1 CagA Virulence cag PAI Protein 0.0 78
cagA YP_005774524.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 78
HP0547 BAD13853.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 76
cagA BAC10427.1 CagA Virulence cag PAI Protein 0.0 75
cagA BAC10423.1 CagA Virulence cag PAI Protein 0.0 71
cagA BAC10430.1 CagA Virulence cag PAI Protein 0.0 70
cagA BAC10424.1 CagA Virulence cag PAI Protein 0.0 70
cagA BAC10422.1 CagA Virulence cag PAI Protein 0.0 69
HP0547 BAD13826.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 69

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
C730_02825 YP_006936077.1 cag pathogenicity island protein (cag26) VFG0306 Protein 0.0 100