Gene Information

Name : C730_02725 (C730_02725)
Accession : YP_006936057.1
Strain : Helicobacter pylori Rif2
Genome accession: NC_018938
Putative virulence/resistance : Virulence
Product : cag pathogenicity island protein (cag8)
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 560012 - 561580 bp
Length : 1569 bp
Strand : -
Note : COG3504 Type IV secretory pathway, VirB9 components

DNA sequence : 
ATGGGGCAGGCATTTTTTAAAAAAATTGTTGGCTGTTTCTGTCTTGGTTATTTATTTTTATCTAGCGCAATAGAAGCAGC
AGCACTTGACATTAAGAATTTTAATCGTGGTAGGGTGAAAGTGGTGAATAAGAAGATTGCTTATTTGGGAGATGAAAAAC
CTATTACGATTTGGACTTCATTAGACAATGTTACCGTGATCCAACTTGAAAAAGATGAAACTATTTCTTACATCACAACA
GGTTTCAATAAAGGTTGGAGTATTGTGCCTAATTCTAATCATATATTCATTCAACCTAAATCGGTAAAAAGTAATCTCAT
GTTTGAAAAAGAAGCAGTGAATTTTGCCCTAATGACAAGAGATTACCAAGAATTTTTAAAAACAAAAAAACTTATCGTAG
ATGCGCCTGACCCTAAAGAATTAGAAGAACAAAAAAAAGCTCTAGAAAAAGAAAAAGAAGCTAAAGAACAAGCGCAAAAA
GCACAAAAAGATAAAAGAGAAAAAAGAAAAGAAGAGCGTGCAAAAAATAGAGCCAATTTAGAAAATCTCACTAACGCTAT
GAGTAACCCACAAAATTTGAGCAATAACAAAAATCTTAGCGAATTTATCAAGCAACAACGAGAAAATGAATTAGACCAAA
TGGAACGACTAGAGGACATGCAAGAACAGGCTCAAGCTAATGCGCTCAAACAAATTGAAGAACTCAACAAGAAACAAGCT
GAAGAGACAATCAAGCAAAGAGCCAAAGATAAAATCAATATTAAGACAGATAAGCCTCAAAAAAGCCCTGAGGATAACTC
CATAGAATTATCTCCTAGCGATAGCGCTTGGAGAACTAATCTTGTTGTGCGGACTAATAAAGCCTTGTATCAATTCATTT
TGAGAATAGCTCAAAAAGACAATTTTGCTTCAGCGTATCTAACAGTCAAATTAGAATACCCACAAAGACACGAAGTCTCT
AGCGTTATTGAAGAGGAGTTAAAAAAGAGAGAAGAAGCAAAGAGGCAGAAAGAATTGATTAAGCAAGAAAATCTTAACAC
CACAGCCTACATCAATAGAGTGATGATGGCGAGCAATGAACAGATTATCAACAAAGAAAAAATAAGAGAAGAAAAGCAAA
AAATTATCTTAGATCAAGCAAAGGCGCTAGAGACTCAATATGTGCATAATGCCTTAAAAAGAAACCCCGTGCCTAGAAAC
TACAACTACTACCAAGCGCCTGAAAAACGCTCTAAACATATTATGCCCTCTGAAATTTTTGATGATGGCACATTCACTTA
TTTTGGTTTCAAAAACATCACTCTCCAACCTGCTATTTTTGTGGTTCAACCTGATGGGAAATTGAGCATGACTGATGCCG
CCATTGATCCTAACATGACCAATTCAGGATTGAGATGGTATAGAGTTAATGAAATTGCAGAAAAATTTAAGCTCATTAAA
GACAAAGCCCTTGTAACAGTAATCAATAAAGGCTATGGGAAAAATCCATTGACAAAAAATTACAATATCAAAAACTATGG
TGAATTGGAGCGTGTGATTAAAAAGCTCCCTCTTGTCAGAGATAAATAA

Protein sequence : 
MGQAFFKKIVGCFCLGYLFLSSAIEAAALDIKNFNRGRVKVVNKKIAYLGDEKPITIWTSLDNVTVIQLEKDETISYITT
GFNKGWSIVPNSNHIFIQPKSVKSNLMFEKEAVNFALMTRDYQEFLKTKKLIVDAPDPKELEEQKKALEKEKEAKEQAQK
AQKDKREKRKEERAKNRANLENLTNAMSNPQNLSNNKNLSEFIKQQRENELDQMERLEDMQEQAQANALKQIEELNKKQA
EETIKQRAKDKINIKTDKPQKSPEDNSIELSPSDSAWRTNLVVRTNKALYQFILRIAQKDNFASAYLTVKLEYPQRHEVS
SVIEEELKKREEAKRQKELIKQENLNTTAYINRVMMASNEQIINKEKIREEKQKIILDQAKALETQYVHNALKRNPVPRN
YNYYQAPEKRSKHIMPSEIFDDGTFTYFGFKNITLQPAIFVVQPDGKLSMTDAAIDPNMTNSGLRWYRVNEIAEKFKLIK
DKALVTVINKGYGKNPLTKNYNIKNYGELERVIKKLPLVRDK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
HP0528 NP_207324.1 cag pathogenicity island protein (cag8) Virulence cag PAI Protein 0.0 100
HP0528 BAD13807.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
HP0528 BAD13889.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
HP0528 BAD13861.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cagX YP_005774541.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
HP0528 BAD13834.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cagX YP_005775731.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cag8 AAR03863.1 Cag8 Virulence cag PAI Protein 0.0 99
orf15 NP_223195.1 cag island protein Virulence cag PAI Protein 0.0 99
cagX AGC69795.1 cag pathogenicity island protein X Virulence cag PAI Protein 0.0 99
cagX YP_003728736.1 cag pathogenicity island protein X Virulence cag PAI Protein 0.0 99
HP0528 BAD14027.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cag8 AAR03921.1 Cag8 Virulence cag PAI Protein 0.0 99
cagX YP_005777272.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cag-X AAF80199.1 Cag-X Virulence cag PAI Protein 0.0 99
HP0528 BAD13971.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cag8 AAR03952.1 Cag8 Virulence cag PAI Protein 0.0 99
HP0528 BAD14053.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
HP0528 BAD13999.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cag8 AAR03891.1 Cag8 Virulence cag PAI Protein 0.0 99
HP0528 BAD13916.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
HP0528 BAD13780.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 98
HP0528 BAD13944.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 98
cagX YP_005779062.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 98

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
C730_02725 YP_006936057.1 cag pathogenicity island protein (cag8) VFG0288 Protein 0.0 100