Gene Information

Name : guaA (A20_0955)
Accession : YP_006932990.1
Strain : Streptococcus pyogenes A20
Genome accession: NC_018936
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : -
COG ID : -
EC number : 6.3.5.2
Position : 904568 - 906130 bp
Length : 1563 bp
Strand : +
Note : [F] COG0519 GMP synthase, PP-ATPase domain/subunit

DNA sequence :
ATGACTGAAATTTCAATTTTGAATGATGTTCAAAAAATTATCGTTCTTGATTATGGTAGCCAGTACAATCAGCTTATTGC
TAGACGTATTCGAGAGTTTGGTGTTTTCTCCGAACTAAAAAGCCATAAAATCACCGCTCAAGAACTTCGTGAGATCAATC
CCATAGGTATCGTTTTATCAGGAGGGCCTAACTCTGTTTACGCTGATAACGCCTTTGGCATTGACCCTGAAATCTTTGAA
CTAGGGATTCCGATTCTTGGTATCTGTTACGGTATGCAATTAATCACCCATAAATTAGGTGGTAAAGTTGTTCCTGCTGG
ACAAGCTGGTAATCGTGAATACGGTCAGTCAACCCTTCATCTTCGTGAAACGTCAAAATTATTTTCAGGCACACCTCAAG
AACAACTCGTTTTGATGAGCCATGGTGATGCTGTTACTGAAATTCCAGAAGGTTTCCACCTTGTTGGAGACTCAAATGAC
TGTCCCTATGCAGCTATTGAAAATACTGAGAAAAACCTTTACGGTATTCAGTTCCACCCAGAAGTGAGACACTCTGTTTA
TGGAAATGACATTCTTAAAAACTTTGCTATATCAATTTGTGGCGCGCGTGGTGATTGGTCAATGGATAATTTTATTGACA
TGGAAATTGCTAAAATTCGTGAAACTGTAGGCGATCGTAAAGTTCTTCTAGGTCTTTCTGGTGGAGTTGATTCTTCAGTT
GTTGGTGTTCTACTTCAAAAAGCTATCGGTGACCAATTAACTTGTATTTTCGTTGATCACGGTCTTCTTCGTAAAGACGA
GGGCGATCAAGTTATGGGAATGCTTGGGGGCAAATTTGGCCTAAATATTATCCGTGTGGATGCTTCAAAACGTTTCTTAG
ACCTTCTTGCAGACGTTGAAGATCCTGAGAAAAAACGTAAAATTATTGGTAATGAATTTGTCTATGTTTTTGATGATGAA
GCCAGCAAATTAAAAGGTGTTGACTTCCTTGCCCAAGGAACACTTTATACTGATATCATTGAGTCAGGAACAGAAACTGC
TCAAACCATCAAATCACATCACAATGTGGGTGGTCTCCCCGAAGACATGCAGTTTGAATTGATTGAGCCCTTAAACACTC
TTTTCAAAGATGAAGTTCGAGCGCTTGGAATCGCTCTTGGAATGCCTGAAGAAATTGTTTGGCGCCAACCATTTCCAGGT
CCTGGACTTGCTATCCGTGTCATGGGAGCAATTACTGAAGAAAAACTTGAAACCGTTCGCGAATCAGACGCTATCCTTCG
TGAAGAAATTGCTAAGGCTGGACTTGATCGTGACGTGTGGCAATACTTTACAGTTAACACAGGTGTCCGTTCTGTAGGCG
TCATGGGAGATGGTCGTACTTATGATTATACCATCGCCATTCGTGCTATTACGTCTATTGATGGTATGACAGCTGACTTT
GCTCAACTTCCTTGGGATGTCTTGAAAAAAATCTCAACACGTATCGTAAATGAAGTTGACCACGTTAACCGTATCGTCTA
CGACATCACAAGTAAACCACCCGCAACAGTTGAATGGGAATAA

Protein sequence :
MTEISILNDVQKIIVLDYGSQYNQLIARRIREFGVFSELKSHKITAQELREINPIGIVLSGGPNSVYADNAFGIDPEIFE
LGIPILGICYGMQLITHKLGGKVVPAGQAGNREYGQSTLHLRETSKLFSGTPQEQLVLMSHGDAVTEIPEGFHLVGDSND
CPYAAIENTEKNLYGIQFHPEVRHSVYGNDILKNFAISICGARGDWSMDNFIDMEIAKIRETVGDRKVLLGLSGGVDSSV
VGVLLQKAIGDQLTCIFVDHGLLRKDEGDQVMGMLGGKFGLNIIRVDASKRFLDLLADVEDPEKKRKIIGNEFVYVFDDE
ASKLKGVDFLAQGTLYTDIIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRALGIALGMPEEIVWRQPFPG
PGLAIRVMGAITEEKLETVRESDAILREEIAKAGLDRDVWQYFTVNTGVRSVGVMGDGRTYDYTIAIRAITSIDGMTADF
AQLPWDVLKKISTRIVNEVDHVNRIVYDITSKPPATVEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-174 69
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 1e-174 69
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 4e-175 69
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-119 52