Gene Information

Name : lysS (A20_0537c)
Accession : YP_006932576.1
Strain : Streptococcus pyogenes A20
Genome accession: NC_018936
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : -
COG ID : -
EC number : 6.1.1.6
Position : 478664 - 480157 bp
Length : 1494 bp
Strand : -
Note : [J] COG1190 Lysyl-tRNA synthetase (class II)

DNA sequence :
ATGTCTAATCAACACATCGAAGAATTAAATGACCAACAGATTGTCCGTCGTGAAAAAATGACGGCGCTGGCTGAACAAGG
AATTGATCCTTTCGGTAAACGCTTTGACCGCACAGCCAATTCTGCTGAATTAAAAGAAAAGTATGCTGATAAAACAAAAG
AAGAATTACATGAGTTAAACGAAACAGCTATTGTTGCTGGCCGCTTGATGACAAAACGTGGCAAAGGTAAGGTTGGTTTT
GCTCATCTTCAAGACCGTGAAGGCCAAATCCAACTTTATGTTCGCAAGGACTCTGTTGGCGAAGACAACTATGAAATCTT
CAAAAAAGCCGATTTAGGCGACTTTATCGGCGTTGAAGGCGAAGTCATGCGTACAGACATGGGCGAGTTGTCAATCAAGG
CAACCAAGTTGACTCACCTTTCTAAATCACTTCGTCCTCTTCCTGAAAAATTCCACGGATTAACTGATATTGAAACCATT
TACCGTAAGCGTCACCTTGATTTAATTTCAAATCGTGAAAGCTTTGACCGCTTCGTGACCCGTTCCAAAATGATTTCAGA
AATCCGTCGTTATTTAGACGGTCTTGATTTCCTAGAAGTAGAAACGCCTGTGCTTCATAACGAGGCTGGTGGTGCTGCTG
CTCGTCCTTTCGTTACTCACCATAATGCTCAAAACATTGATATGGTGCTTCGTATCGCAACAGAACTTCATTTGAAACGT
TTGATTGTTGGTGGTATGGAACGTGTCTATGAAATTGGTCGTATCTTCCGTAACGAGGGAATGGATGCTACTCATAATCC
TGAGTTCACTTCTATTGAGGTTTACCAAGCCTATGCAGACTATCTTGATATCATGAACCTGACAGAAGGCATTATCCAAC
ATGCTGCTAAAGCTGTTAGAGGTGATGGCCCTATTGATTATCAAGGAACTGAAATCCGTATCAATGAACCTTTCAAACGT
GTTCACATGGTAGATGCTATCAAGGAAGTGACAGGTGCTGATTTCTGGCCTGAAATGACTGTCGAAGAAGCTATTGCACT
TGCCAAAGAAAAACAGGTCCCACTCGAAAAACACTTCATAAGTGTCGGACATATCATCAACGCTTTCTTCGAGGAATTTG
TTGAAGAAACCTTGGTCCAACCAACCTTTGTGTTTGGTCATCCTGTTGAAGTATCGCCTTTGGCTAAGAAGAATCCAGAA
GATACCCGCTTCACCGACCGCTTCGAACTTTTCATCATGACCAAAGAATACGCCAATGCTTTCACAGAGTTGAATGATCC
CATTGACCAATTATCTCGTTTTGAAGCACAAGCACAAGCTAAAGAACTTGGTGATGACGAAGCAACTGGCATTGACTACG
ACTTCGTTGAAGCTCTTGAATATGGTATGCCGCCAACCGGTGGACTCGGAATCGGGATTGATCGTCTTTGCATGTTATTA
ACAAACACAACAACAATCAGAGATGTGCTTTTATTCCCAACGATGAAACCTTAA

Protein sequence :
MSNQHIEELNDQQIVRREKMTALAEQGIDPFGKRFDRTANSAELKEKYADKTKEELHELNETAIVAGRLMTKRGKGKVGF
AHLQDREGQIQLYVRKDSVGEDNYEIFKKADLGDFIGVEGEVMRTDMGELSIKATKLTHLSKSLRPLPEKFHGLTDIETI
YRKRHLDLISNRESFDRFVTRSKMISEIRRYLDGLDFLEVETPVLHNEAGGAAARPFVTHHNAQNIDMVLRIATELHLKR
LIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQAYADYLDIMNLTEGIIQHAAKAVRGDGPIDYQGTEIRINEPFKR
VHMVDAIKEVTGADFWPEMTVEEAIALAKEKQVPLEKHFISVGHIINAFFEEFVEETLVQPTFVFGHPVEVSPLAKKNPE
DTRFTDRFELFIMTKEYANAFTELNDPIDQLSRFEAQAQAKELGDDEATGIDYDFVEALEYGMPPTGGLGIGIDRLCMLL
TNTTTIRDVLLFPTMKP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 7e-106 47

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_006932576.1 lysyl-tRNA synthetase VFG1668 Protein 4e-106 47