Gene Information

Name : polA.2 (A20_1498c)
Accession : YP_006933520.1
Strain : Streptococcus pyogenes A20
Genome accession: NC_018936
Putative virulence/resistance : Unknown
Product : DNA polymerase A family protein
Function : -
COG functional category : -
COG ID : -
EC number : 2.7.7.7
Position : 1416430 - 1418352 bp
Length : 1923 bp
Strand : -
Note : [L] COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains

DNA sequence :
ATGAGACATTTAAATATTGATATTGAAACCTATAGTTCGAATGACATCAAAAATGGGGTTTACAAGTACGCTGACGCTGA
AGATTTTGAGATTTTACTTTTCGCTTACTCTATAGATGGCGGAGAAGTAGAGTGCCTTGATTTGACAAGGCAGTCTCTAC
CTGAAGACATCAAAGATATGTTATTTGATGATAAAGTCCGAAAGCACGCCTTTAATGCCCAATTCGAAAGAGTTTGTCTC
AGTCGTTACCTCGGCCTACCTTACTATTTAGATCCCGCACAATGGCAGTGTACGATGGTACTTGCACAAGAGCTGGGTCT
GCCTGCAAGCCTGGAAAAATGTGCGCTGTATTTAAAATTAGCGCAAGAAAAAGACGCAGCAGGTAAAAATCTCATTAAAT
ATTTTTCGGTACCCTGCAAGCCTACAAAAGCCAACGGGGGAAGAACGAGGAACCTGCCCGAGCATGATCCTGGAAAATGG
CAAATGTTTATTAACTACTGTATGCAAGACGTTGTTGTTGAGATGGCAATTGCCGAAAAACTAGAGTCAGTTCCTGTGCA
CGACCGTGAGTGGGATTACTACGTCTGCGACCAGAGAATCAACGACAGAGGCGTGGCACTTGATAAAGAGTTAGTTGCTT
CGGCTTTGTATTGTAAAGATGTTAAGATGGAAAGTTTGTCTGGTGAACTAAAGGCTCTAACAGGACTTGATAATCCTAAT
AGCAGGGCGCAGCTGCTACCGTGGCTAAAAGAACACGGTTATTCGGCTAATGGGCTGACTAAAGCTGATGTTGAACAGGA
ACTTAAGAAGGCCGAAGGAGAGCTTAAGAGAGTTTTAGAACTTAAACTACAAACCGCGATGTCAAGTCTAAAAAAATATG
AAGCTATGGAAAGAGCTATGTGCTCAGACGGACGAGTTCATGGGCTACTTCAGTTTTACGGGGCTAGCCGGACAGGAAGA
TGGGCGGGCAGAGTTGTCCAAGTACAGAACTTAGCTAGGAATTATATAAAGGATCTAGATGATGCTAGAGAGTATGTTAA
AAAGCGTGATATTGATGCTGTGGAGATTTTATACGATAGCCTTAACGACACTTTAAAGCAGCTCGTGCGAACGGCACTCG
TGGCTAAAGATGGCTATACCTTCTATGTCTCTGACTTCTCGGCGATTGAGGCTAGGGTGATTGCATGGTTTGCTGGAGAG
CAGTGGAGGCTTGACGTGTTTTCTACGCACGGGAAAATCTACGAGGCGTCTGCCAGTCAGATGTTCGGAATTCCAATTGA
GGAGATTGACAAGGAACTACGCCAAAAGGGCAAAATTTCAGAGTTAGCACTTGGCTATCAAGGAGGTCCTGGAGCGCTTA
AGCAGATGGGGGCTCTAAATATGGGAGTCAAGGAAGAGGAGCTTCAAGGGTTAGTTGATGACTGGCGCAGGGCCAATAAG
AAAATCGTCCAATTTTGGAAAGACGTACAAAGAGCCGCCATCAAAGCCATCAAATCGAGAGCACCGATAAAACTTGGAAA
AATACGATTTAGATACCGGAAAGGTTTCCTCTTTATAACATTGCCTAGCGGTAGGAACTTAGCTTATGCAAGAGCCAAGG
TTGAGCCAGGCGACTATGGAGACAAAATCATCTATGAGGGCCAAGGAGATAGGGCCTATTTCACAGCGCAAGAGACGTAC
GGCGGTAAGCTTGTCGAAAATATCGTTCAGGCGACGGCCAGGGATATTCTAGCTGAAGCGCTTCTGAGGATTGAAGCTGC
AGGCTATGATGTTGTTTTCCACGTTCATGATGAGGCTATTATCGAAGGTTCAGGCCTGATAATCGAAGAGGTTAATGATT
TGATGGCTCAGGCTCCTGAATGGGCGGAGGGTCTTCCTTTAAATAGCGAAGGCTATGTAACAAAGTATTATATGAAGGAT
TAG

Protein sequence :
MRHLNIDIETYSSNDIKNGVYKYADAEDFEILLFAYSIDGGEVECLDLTRQSLPEDIKDMLFDDKVRKHAFNAQFERVCL
SRYLGLPYYLDPAQWQCTMVLAQELGLPASLEKCALYLKLAQEKDAAGKNLIKYFSVPCKPTKANGGRTRNLPEHDPGKW
QMFINYCMQDVVVEMAIAEKLESVPVHDREWDYYVCDQRINDRGVALDKELVASALYCKDVKMESLSGELKALTGLDNPN
SRAQLLPWLKEHGYSANGLTKADVEQELKKAEGELKRVLELKLQTAMSSLKKYEAMERAMCSDGRVHGLLQFYGASRTGR
WAGRVVQVQNLARNYIKDLDDAREYVKKRDIDAVEILYDSLNDTLKQLVRTALVAKDGYTFYVSDFSAIEARVIAWFAGE
QWRLDVFSTHGKIYEASASQMFGIPIEEIDKELRQKGKISELALGYQGGPGALKQMGALNMGVKEEELQGLVDDWRRANK
KIVQFWKDVQRAAIKAIKSRAPIKLGKIRFRYRKGFLFITLPSGRNLAYARAKVEPGDYGDKIIYEGQGDRAYFTAQETY
GGKLVENIVQATARDILAEALLRIEAAGYDVVFHVHDEAIIEGSGLIIEEVNDLMAQAPEWAEGLPLNSEGYVTKYYMKD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SEQ_2073 YP_002747288.1 phage DNA polymerase Not tested ¥ÕSeq4 Protein 0.0 97
polA YP_494120.1 phage related DNA polymerase family A Not tested ¥ÕSa2 Protein 3e-158 55
MW1425 NP_646242.1 DNA polymerase Not tested ¥ÕSa2 Protein 3e-159 55