Gene Information

Name : guaA (Tph_c08410)
Accession : YP_006919570.1
Strain : Thermacetogenium phaeum DSM 12270
Genome accession: NC_018870
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : -
COG ID : -
EC number : 6.3.5.2
Position : 869260 - 870837 bp
Length : 1578 bp
Strand : +
Note : glutamine-hydrolizing

DNA sequence :
ATGCCCTCCCTTTGCAGGAGGAGAGCAGCCGAGGTGAAGTGCATGAGTGAGCGGGATCTGATTTTGGTTGTAGATTTCGG
AGGGCAGTATACCCAGCTTATTGCCCGGCGGATCCGGGAGGCCGGGGTTTACTGCGAAATTGTGCCCTATACGGCGGCGT
GGGAGGAGCTCCGGGCAAAACGGCCGCGGGGGCTGGTGCTTTCGGGTGGGCCGGCGAGTGTCTATTCCGAGAAGGCCCCG
CAATGCGATCCCAGGCTCCTGAGGGGAGGGGTTCCGGTGCTGGGCATCTGCTACGGTATGCAGCTGATGGCCTTTCTCCT
CAAAGGAAGCGTCCGCAGGGGGGAAAGGCGGGAGTACGGCCGTGTGCAGGTTACCGTCCGGAGACAGGAGGCCATCTTCA
AGGGGCTCCCGCGAGAGATGCCCGTCTGGATGAGCCATGGTGACCTGGTAGAGGCCCCTCCTCCGGGTTTTACGGTCGCC
GCAACATCCGAGGGAACACCGGTGGCGGCCATGTTCGATGAACAGCGCCGCCTGTTCGGGGTGCAGTTTCATCCCGAGGT
GCAGCACACCCCCTTCGGGAAGGATATCTTGCGAAACTTTCTCTATGACATCTGCAGCTGCAAGGGGGATTGGACGCCGG
CATCCTTTATCGCCGGGCAGATCGAAGAGATCAGGAAGATCGTCGGGAACGGCAGGGTTGTCGGGGCTTTGAGCGGTGGG
GTGGACTCCACCGTAGCGGCAACGCTCGTCCACCGAGCAATCGGGGAGAGGTTGACCTGCATCTTCGTTGATCACGGCCT
GCTCCGGAAGGGGGAGCGGGAAGAGGTTGAGTGGACGATGCGGGAGCGGTTGGGGGTTAAGCTGATTACCGTCGAGGCCG
GGGAGCGCTTCCTGGCCAAGCTCTCCGGTGTCACCGATCCTGAAGAGAAGCGGAAAATAATCGGGCATGAGTTCATCAGG
GTCTTCGAGGAAGAGGCGTCCCGCCTCGGCGAGCTGGATTTTCTCCTGCAGGGAACCCTCTACCCCGATGTCATCGAATC
GGGAACTCCCACCGCTGCCGTGATCAAGAGCCACCACAATGTAGGGGGGCTGCCCGAGGACCTCAAGCTGCGCCTTTTGG
AGCCGCTGCGCTGGCTTTTTAAGGATGAGGTGCGCCGGGTGGGGCTGGAACTCGGCCTGCCGGAAGAGATCATCTGGCGC
CAGCCCTTCCCCGGACCGGGTTTGGCGGTAAGGGTGCTGGGTGAGGTGACCCCGGAGAAGCTGGCGATGGTCAGGGAGGC
GGACTATATCCTGCGCACGGAGATCCGCCGTGCCGGGCTCGAGCGGGAGATCTGGCAGTGCTTTGCCGTCCTGCTTCCGG
TCAGAAGCGTCGGAGTGATGGGGGACGAGCGGACGTATGCCCATCCTGTCGTGATCCGGGCGGTGACCAGCGAGGATGCC
ATGACTGCCGATTGGGCGCGCCTGCCGCACGATCTCCTGGAGCGGATCGCCGGCCGCATCGTCGGGGAGGTTCCGGGGAT
CAACAGGGTGCTCTATGATATCACATCCAAGCCTCCGGGGACTATCGAGTGGGAATAA

Protein sequence :
MPSLCRRRAAEVKCMSERDLILVVDFGGQYTQLIARRIREAGVYCEIVPYTAAWEELRAKRPRGLVLSGGPASVYSEKAP
QCDPRLLRGGVPVLGICYGMQLMAFLLKGSVRRGERREYGRVQVTVRRQEAIFKGLPREMPVWMSHGDLVEAPPPGFTVA
ATSEGTPVAAMFDEQRRLFGVQFHPEVQHTPFGKDILRNFLYDICSCKGDWTPASFIAGQIEEIRKIVGNGRVVGALSGG
VDSTVAATLVHRAIGERLTCIFVDHGLLRKGEREEVEWTMRERLGVKLITVEAGERFLAKLSGVTDPEEKRKIIGHEFIR
VFEEEASRLGELDFLLQGTLYPDVIESGTPTAAVIKSHHNVGGLPEDLKLRLLEPLRWLFKDEVRRVGLELGLPEEIIWR
QPFPGPGLAVRVLGEVTPEKLAMVREADYILRTEIRRAGLEREIWQCFAVLLPVRSVGVMGDERTYAHPVVIRAVTSEDA
MTADWARLPHDLLERIAGRIVGEVPGINRVLYDITSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 2e-138 60
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-138 60
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 1e-138 60
guaA NP_938969.1 GMP synthase Not tested Not named Protein 1e-129 58