Gene Information

Name : bcrD (BN117_1374)
Accession : YP_006895356.1
Strain : Bordetella parapertussis Bpp5
Genome accession: NC_018828
Putative virulence/resistance : Virulence
Product : type III secretion pore protein
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1493892 - 1495991 bp
Length : 2100 bp
Strand : -
Note : -

DNA sequence :
ATGACGAGCAAGAAATCCATTCTCCGCCTGCAACGCGCGGTGGCGCTGGCCACCAGCCGCAACGACATCGTACTGGCCGT
GCTCATCGTGGCGATCGTCTTCATGATGATCCTGCCGTTGCCCACGACGCTGGTCGACGTGCTGATCGGTGCGAACATGA
CGCTGTCCGCGGTCCTGCTGATGGTCGCGATGTACCTGCCTTCGCCCCTGGCGTTTTCCTCGTTCCCTTCGGTCCTGCTG
GTCACCACGCTGTTCCGGCTGGGCATCTCCATCGCGACCACGCGGCTGATCCTCCTGCAAGGCGATGCCGGCCACATCAT
CGAGACCTTCGGCAACTTCGTGGTGGGCGGCAACCTGATCGTCGGCCTGGTGGTTTTCCTCATCCTCACGATCGTGCAGT
TCGTGGTCATCACCAAAGGCGCGGAGCGGGTGGCCGAAGTCGCCGCGCGCTTCTCGCTGGACGCCATGCCCGGCAAGCAG
ATGTCCATCGACGCGGACTTGCGCGCGGGCACCATAGACATGGACGAAGCCCGCCGCCGACGCCGTACGGTCGAGAAGGA
AAGCCAACTGTATGGCGCCATGGACGGCGCGATGAAGTTCGTCAAGGGCGATGCCATCGCCGGCCTGATCATCGTTGCCG
TCAACCTGCTTGGCGGCATGCTGGTCGGCGTGCTGCAGCGCGGCCTGAGCGCCGGCGAGGCCGTGCAGACATATGCCATC
CTGACCATAGGCGACGGGCTCATCGCGCAGATCCCGGCGCTGTTCATCGCCATCTGCGCGGGAATCATCGTGACGCGGGT
GCAGACCGGGGATGGCCCCTCCAACGTAGGCACCGACATCGGCGCACAAGTGCTGGCGCAGCCTCGCGCCCTGGTCATTG
CCGGCGCGATCTCGGCAGGCCTGGGCCTCATTCCCGGCATGCCCACGCTGGTCTTCTTCGCCCTGGCCGCCGTGGTGGGC
ACCATCGGTTTCGTACTGCTGCGCGCATCCCAGCGTCCGCCCGAAGGCGCCGGGCCCGCGCTCGCCGGCATGGCTGCCGA
CGGCCAGCCCCGCACCCGCGCGCCGGCGGATGGACAGGCGGAATTCGCTCCCACCGTCCCGCTGATCATCGACGTGGCCG
CGCGGCTGCAGCCCCGGTTCGAGCCGGCCACCCTCACCGACGATCTGCTGCAGATCCGGCGGGCGCTCTATTTCGACTTG
GGCGTGCCATTTCCCGGCATCCAGTTGCGCTTCACCGAAGCGCTGGCCGCCAATACCTACACCATCGTGCTGTCGGAGAT
CCCGGTGGCGCAGGGGATGTTGCGCGACGATGCCGTGCTGGTGCGGGACACCGAGCAGAACCTGCAGGCCCTGCGGATCG
CATACGAAACGGGCGCGGCCTTTCTGCCCGATACGCCCACGATCTGGGTTACAGCCAGTCTGACCGGCGCCTTGCGCGAT
GCAGGTATTCCTTACCTGGGTATCAGCCAGATCTTGACTTGGCACTTGGCATATGTACTGAAAAAATATTCAGCCGACTT
CATCGGCATCCAGGAAACCCGGTTTCTGCTTTCGGCCATGGAAGAACGATTTCCCGATCTGGTCAAGGAGTGCCTGCGCG
TCATGCCGGTGCAGAAGATTGCCGAAATCCTGCAGCGCCTTGTTTCCGAGGAAGTGTCGATACGCAACCTGCGCGCTGTC
CTGGAAGCGCTGGTCGAATGGGGCCAGAAGGAAAAGGATACCGTCCTGCTTACGGAGTATGTCCGAATCGCACTCAAGCG
CTATATCAGCTACAAGTACACCAGCGGCCACAATATCCTGCCCGCCTACCTGCTGGCCCCCAAGGTCGAGGAAACCGTGC
GCGCCGCCATCCGGCAGACCGCCGCCGGCAGTTATCTCGCCCTCGATCCGGACACGACACGCCGGCTGGTCGAGCACATA
CGCCAATGTGTCGGCGATCTGGCCGCCGGCGCGAGCCGTCCCGTCTTGCTGACGTCGATGGACATCCGGCGCTACACGCG
CAAGATGATCGAAGCCGATCTCTACGCCCTGCCGGTGCTGTCCTACCAGGAACTGACGCCGGAGATCAATGTACAGCCCC
TGGGCAGGGTGGATCTATGA

Protein sequence :
MTSKKSILRLQRAVALATSRNDIVLAVLIVAIVFMMILPLPTTLVDVLIGANMTLSAVLLMVAMYLPSPLAFSSFPSVLL
VTTLFRLGISIATTRLILLQGDAGHIIETFGNFVVGGNLIVGLVVFLILTIVQFVVITKGAERVAEVAARFSLDAMPGKQ
MSIDADLRAGTIDMDEARRRRRTVEKESQLYGAMDGAMKFVKGDAIAGLIIVAVNLLGGMLVGVLQRGLSAGEAVQTYAI
LTIGDGLIAQIPALFIAICAGIIVTRVQTGDGPSNVGTDIGAQVLAQPRALVIAGAISAGLGLIPGMPTLVFFALAAVVG
TIGFVLLRASQRPPEGAGPALAGMAADGQPRTRAPADGQAEFAPTVPLIIDVAARLQPRFEPATLTDDLLQIRRALYFDL
GVPFPGIQLRFTEALAANTYTIVLSEIPVAQGMLRDDAVLVRDTEQNLQALRIAYETGAAFLPDTPTIWVTASLTGALRD
AGIPYLGISQILTWHLAYVLKKYSADFIGIQETRFLLSAMEERFPDLVKECLRVMPVQKIAEILQRLVSEEVSIRNLRAV
LEALVEWGQKEKDTVLLTEYVRIALKRYISYKYTSGHNILPAYLLAPKVEETVRAAIRQTAAGSYLALDPDTTRRLVEHI
RQCVGDLAAGASRPVLLTSMDIRRYTRKMIEADLYALPVLSYQELTPEINVQPLGRVDL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lssD AAO18050.1 LssD Virulence TTSS locus Protein 2e-180 59
YPO0266 YP_002345347.1 secretion system apparatus protein SsaV Virulence Not named Protein 2e-116 48
hrcV AAT96337.1 HrcV Virulence S-PAI Protein 2e-99 46
hrcV AAT96256.1 HrcV Virulence S-PAI Protein 1e-99 46
hrcV AAT96297.1 HrcV Virulence S-PAI Protein 3e-99 46
hrcV NP_636603.1 protein HrcV Virulence Hrp PAI Protein 5e-100 45
XC_3013 YP_244081.1 HrcV protein Virulence Hrp PAI Protein 5e-100 45
hrcV ABA47273.1 HrcV Virulence S-PAI Protein 3e-95 45
hrcV YP_362156.1 HrcV protein Virulence Hrp PAI Protein 1e-96 44
hrcV AAP34346.1 HrcV Virulence Hrp PAI Protein 1e-94 44
hrcV BAB07859.1 HrcV Virulence Hrp PAI Protein 8e-96 44
hrcV NP_640760.1 HrcV protein Virulence Hrp PAI Protein 1e-94 44
hrcV YP_198723.1 protein HrcV Virulence Hrp PAI Protein 1e-95 44
ssaV CAA70536.1 secretion system apparatus Virulence SPI-2 Protein 4e-100 43
ssaV NP_460379.1 secretion system apparatus protein SsaV Virulence SPI-2 Protein 6e-100 43
ssaV YP_216422.1 secretion system apparatus protein SsaV Virulence SPI-2 Protein 5e-100 43
invA AAS66860.1 InvA Not tested SSR-2 Protein 2e-90 43
escV AAC38382.1 EscV Virulence LEE Protein 8e-99 43
hrcV AAR25631.1 type III secretion protein HrcV Not tested Not named Protein 3e-93 43
invA NP_457290.1 possible secretory protein (associated with virulence) Virulence SPI-1 Protein 7e-99 43
invA NP_806499.1 virulence-associated secretory protein Virulence SPI-1 Protein 7e-99 43
invA NP_461817.1 needle complex export protein Virulence SPI-1 Protein 7e-99 43
invA YP_217815.1 invasion protein Virulence SPI-1 Protein 7e-99 43
hrcV ABQ88352.1 HrcV Virulence Hrp PAI Protein 2e-97 43
hrpI AAA03015.1 HrpI Virulence Hrp PAI Protein 2e-97 43
hrcV AAG33877.1 HrcV Virulence Hrp PAI Protein 1e-95 43
hrcV NP_791229.1 type III secretion protein HrcV Virulence Hrp PAI Protein 7e-96 43
ssaV NP_456114.1 putative type III secretion protein Virulence SPI-2 Protein 2e-99 42
ssaV NP_805085.1 secretion system apparatus protein SsaV Virulence SPI-2 Protein 2e-99 42
hrcV AAT96139.1 HrcV Virulence T-PAI Protein 1e-98 42
hrcV AAT96193.1 HrcV Virulence T-PAI Protein 9e-99 42
escV CAC81861.1 EscV protein Virulence LEE II Protein 3e-98 42
escV YP_003236089.1 putative translocator EscV Virulence LEE Protein 1e-97 42
escV AAK26714.1 EscV Virulence LEE Protein 2e-98 42
escV NP_290269.1 hypothetical protein Virulence LEE Protein 4e-98 42
escV AAL57541.1 EscV Virulence LEE Protein 2e-98 42
ECs4569 NP_312596.1 hypothetical protein Virulence LEE Protein 4e-98 42
escV CAI43875.1 EscV protein Virulence LEE Protein 2e-98 42
escV YP_003232152.1 T3SS structure protein EscV Virulence LEE Protein 3e-98 42
escV YP_003223476.1 translocator EscV Virulence LEE Protein 2e-98 42
escV AAC31514.1 L0035 Virulence LEE Protein 3e-98 42
escV ACU09459.1 EscV protein Virulence LEE Protein 3e-98 42
unnamed AAL06368.1 EscV Virulence LEE Protein 4e-97 42
escV AFO66414.1 putative LEE-encoded type III secretion system factor Virulence SESS LEE Protein 3e-93 42
escV AFO66296.1 putative LEE-encoded type III secretion system factor Virulence SESS LEE Protein 3e-93 42
hrcV AAB05999.2 HrcV Virulence Hrp PAI Protein 1e-99 42
ECs3731 NP_311758.1 EivA Not tested LIM Protein 2e-98 42
ysaV AAS66840.1 YsaV Not tested SSR-1 Protein 9e-98 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
bcrD YP_006895356.1 type III secretion pore protein VFG0064 Protein 0.0 99
bcrD YP_006895356.1 type III secretion pore protein VFG0198 Protein 9e-167 59
bcrD YP_006895356.1 type III secretion pore protein VFG0384 Protein 7e-177 59
bcrD YP_006895356.1 type III secretion pore protein VFG2126 Protein 6e-130 47
bcrD YP_006895356.1 type III secretion pore protein VFG0514 Protein 3e-100 43
bcrD YP_006895356.1 type III secretion pore protein VFG0729 Protein 4e-99 43
bcrD YP_006895356.1 type III secretion pore protein VFG2461 Protein 4e-97 43
bcrD YP_006895356.1 type III secretion pore protein VFG0557 Protein 3e-99 43
bcrD YP_006895356.1 type III secretion pore protein VFG0813 Protein 2e-98 42
bcrD YP_006895356.1 type III secretion pore protein VFG1780 Protein 2e-96 41
bcrD YP_006895356.1 type III secretion pore protein VFG1006 Protein 2e-93 41