Gene Information

Name : SVEN_5577 (SVEN_5577)
Accession : YP_006881122.1
Strain : Streptomyces venezuelae ATCC 10712
Genome accession: NC_018750
Putative virulence/resistance : Resistance
Product : Dihydropteroate synthase
Function : -
COG functional category : -
COG ID : -
EC number : 2.5.1.15
Position : 6064639 - 6065535 bp
Length : 897 bp
Strand : -
Note : -

DNA sequence :
GTGAGCCCGCTCCAGGCCCGGACGGGCGTACCTCGGCAGCACGAGGACGAAGGCATGGGCATCGTCGCCGGATTGCCTCG
ATGGGATCGGTGCGCCGTCATGGGGGTGGTGAACGTGACCCCCGACTCCTTCTCCGACGGTGGCCGCTGGTTCGACCCGG
CAGCGGCGGTGAAGCACGGGGTGGATCTTGTCGCAGACGGCGCCGACCTGGTCGACGTCGGTGGCGAGTCGACTCGGCCC
GGTGCCTCCCGGGTCGATGAGGAGGAAGAGCTGCGGCGCGTCGTGCCCGTCGTGCGCGCGCTCGCGGCCGAAGGGGTGCT
CGTGTCCGTCGACACCATGCGTGCGTCGGTCGCCGCACGGGCGATCGACGCCGGCGCGGTCCTCGTCAATGACGTCAGCG
GGGGTCTGGCGGACCCCGGAATGGTCCCCGCCGTCGCTGCCGGCGGCGTCCCCTTCGTCGTCATGCACTGGCGCGGTTTC
AGCCGCGACATGAACCGACGAGCGGTGTACGGGGACGTGGTGCGCGAGGTCGTCGCGGAACTCGACGCCCGGGTGGAGGC
CGTGGTGGCCGCGGGCGTTCCCCGGGAGCGGCTGGTGGTGGATCCGGGGCTGGGGTTCGCCAAGCAGCCGGAGCATGATC
TCCGTCTGGTCGCGGGACTGGCCGAGCTCCGTGCGCTGGGCTACCCAGTCCTGGTCGCAGGGTCACGCAAGAGGTTCCTG
GGCCACATCCTGGCCGGCGCGGACGGCACACCTCCCCACGCCCATGACCGGGACGCCGCGACGGCCGCCCTCTCCGCGAT
CGTCGCCCACCGGGGTGCCTGGGCCGTCAGGGTCCATGACGTACGCGCCACGGCGGATGCGGTCAGGGTCGCGCACGCGC
TCGCGTCCGCCTCCTGA

Protein sequence :
MSPLQARTGVPRQHEDEGMGIVAGLPRWDRCAVMGVVNVTPDSFSDGGRWFDPAAAVKHGVDLVADGADLVDVGGESTRP
GASRVDEEEELRRVVPVVRALAAEGVLVSVDTMRASVAARAIDAGAVLVNDVSGGLADPGMVPAVAAGGVPFVVMHWRGF
SRDMNRRAVYGDVVREVVAELDARVEAVVAAGVPRERLVVDPGLGFAKQPEHDLRLVAGLAELRALGYPVLVAGSRKRFL
GHILAGADGTPPHAHDRDAATAALSAIVAHRGAWAVRVHDVRATADAVRVAHALASAS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
sul2 AEZ06044.1 Sul2, sulphonamide-insensitive dihydropteroate synthase Not tested Tn6167 Protein 5e-13 41
sul2 AEA34678.1 dihydropteroate synthase Not tested Not named Protein 4e-13 41
sulI2 AFV47959.1 sulphonamide-insensitive dihydropteroate synthase SulI2 Not tested AbaR25 Protein 4e-13 41
ABK1_0255 YP_005512827.1 Dihydropteroate synthase type-2 Not tested AbaR4d Protein 5e-13 41
BJAB07104_00246 YP_008207711.1 Dihydropteroate synthase-related enzyme Not tested AbaR25 Protein 5e-13 41
BJAB0868_00253 YP_008211579.1 Dihydropteroate synthase-related enzyme Not tested AbaR26 Protein 5e-13 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SVEN_5577 YP_006881122.1 Dihydropteroate synthase AE000516.2.gene3902. Protein 2e-33 58
SVEN_5577 YP_006881122.1 Dihydropteroate synthase NC_002516.2.881715.p Protein 5e-21 48
SVEN_5577 YP_006881122.1 Dihydropteroate synthase NC_008702.1.4608834. Protein 5e-23 47
SVEN_5577 YP_006881122.1 Dihydropteroate synthase NC_011586.7045137.p0 Protein 4e-22 44
SVEN_5577 YP_006881122.1 Dihydropteroate synthase NC_010400.5986775.p0 Protein 8e-23 44
SVEN_5577 YP_006881122.1 Dihydropteroate synthase NC_010410.6003232.p0 Protein 4e-22 44
SVEN_5577 YP_006881122.1 Dihydropteroate synthase NC_011595.7059722.p0 Protein 4e-22 44
SVEN_5577 YP_006881122.1 Dihydropteroate synthase CP001138.1.gene3456. Protein 2e-15 44
SVEN_5577 YP_006881122.1 Dihydropteroate synthase CP000647.1.gene3624. Protein 1e-16 43
SVEN_5577 YP_006881122.1 Dihydropteroate synthase NC_002695.1.916103.p Protein 6e-16 43
SVEN_5577 YP_006881122.1 Dihydropteroate synthase CP000034.1.gene3358. Protein 7e-16 43
SVEN_5577 YP_006881122.1 Dihydropteroate synthase CP002695.1.gene1085. Protein 4e-16 42
SVEN_5577 YP_006881122.1 Dihydropteroate synthase CP004022.1.gene3451. Protein 1e-19 41