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Name : BAST_0774 (BAST_0774) Accession : YP_006864924.1 Strain : Bifidobacterium asteroides PRL2011 Genome accession: NC_018720 Putative virulence/resistance : Resistance Product : ABC transporter, ATP binding protein, probably Macrolide exporter, MacAB Function : - COG functional category : - COG ID : - EC number : 3.6.3.36 Position : 1030527 - 1031285 bp Length : 759 bp Strand : - Note : MacAB also functions (probably with TolC) to export heat-stable enterotoxin II. The crystal structure of MacA is available. MacB is a dimer whose ATPase activity and macrolide-binding capacity are regulated by the membrane fusion protein MacA. Xu et al. ( DNA sequence : ATGATCATCCAAGGGAAAGATGCAACTATGAATAACCCCAACGTAAGCGAAAGCAGAGGCCCGACACCAACGATTGAAGC TACGGGGCTGTCCATGGTGGTCTCCCCGCGCCGCGGCGATTCACTGACCATTCTCAATGACATAGCATTCACTGCCTATC CGGGGGAGATGACCGGCATCATCGGGCCGTCAGGCAGCGGAAAATCGACGCTGCTGTACTGCCTGGCTGGGCTGGAGAAG GCCACTAGCGGCACTGTGCTTCTGCTGGGCAAGGACATAACCCGTCTGGGGCTGTCGGCCATGACCAAGTTCAGACGCCA GCATCTAGGCTTCGTATTCCAGTCCTACAACCTGATCACCAGCATGACAGTCGAACAGAATCTGGCCCTGCCATTCACCC TTCGCGGATCCCGCTTTCCCAGAAAGACGGCGGATTCCCTCTTGAAGTACTTTGGCTTGATCGATCAGAAAAAGAAAAGC GTCACCCTGCTGTCGGGCGGCGAGCAGCAACGTGTTGCCCTGGCCCGCGTCCTGTTATCCGACGTAGACGTGGTATTCGC AGACGAGCCAACTGGCGCTCTGGATCAGGAATCGGGAGAAAAGGTCATATCGGTGCTGAAGGAACTCGCCAACCACGAAG AGAAAACCATCGTACTGGTGACGCATAGCAATGAAGTGGCAGGTCAGTGCGATCGGCTGTTTGCCGTGCGCGATGGCCGT ATCAGCCAATCATTCTCTGCGAAAGCGCCCATGGCATGA Protein sequence : MIIQGKDATMNNPNVSESRGPTPTIEATGLSMVVSPRRGDSLTILNDIAFTAYPGEMTGIIGPSGSGKSTLLYCLAGLEK ATSGTVLLLGKDITRLGLSAMTKFRRQHLGFVFQSYNLITSMTVEQNLALPFTLRGSRFPRKTADSLLKYFGLIDQKKKS VTLLSGGEQQRVALARVLLSDVDVVFADEPTGALDQESGEKVISVLKELANHEEKTIVLVTHSNEVAGQCDRLFAVRDGR ISQSFSAKAPMA |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| Cp1002_1464 | YP_005681730.1 | ABC transporter ATP-binding protein | Not tested | PiCp 5 | Protein | 3e-31 | 42 |
| CpI19_1473 | YP_005685914.1 | ABC transporter ATP-binding protein | Not tested | PiCp 5 | Protein | 8e-32 | 41 |
| CpC231_1466 | YP_005683828.1 | ABC transporter ATP-binding protein | Not tested | PiCp 5 | Protein | 8e-32 | 41 |
| cpfrc_01473 | YP_003783873.1 | hypothetical protein | Not tested | PiCp 5 | Protein | 8e-32 | 41 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| BAST_0774 | YP_006864924.1 | ABC transporter, ATP binding protein, probably Macrolide exporter, MacAB | CP001581.1.gene798.p | Protein | 1e-32 | 43 |
| BAST_0774 | YP_006864924.1 | ABC transporter, ATP binding protein, probably Macrolide exporter, MacAB | NC_012469.1.7686878. | Protein | 1e-30 | 41 |
