Gene Information

Name : guaA (GGS_0939)
Accession : YP_006859583.1
Strain : Streptococcus dysgalactiae RE378
Genome accession: NC_018712
Putative virulence/resistance : Unknown
Product : bifunctional GMP synthase/glutamine amidotransferase protein
Function : -
COG functional category : -
COG ID : -
EC number : 6.3.5.2
Position : 987419 - 988981 bp
Length : 1563 bp
Strand : -
Note : similar to bifunctional GMP synthase/glutamine amidotransferase protein [Streptococcus thermophilus LMG18311]

DNA sequence :
ATGACTGAAATTTCAATTTTGAATGATGTGCAAAAAATTATCGTTCTTGATTATGGTAGCCAGTACAACCAGCTGATTGC
TAGACGTATTCGAGAGTTCGGTGTTTTTTCCGAACTTAAAAGCCATAAAATCACCGCTCAAGAACTTCGTGAGATCAATC
CCATTGGTATCGTTTTATCAGGCGGACCTAACTCTGTCTACGCTGATAACGCCTTTGGTATTGACCCTGAAATCTTTGAA
CTAGGGATTCCGATTCTTGGTATCTGCTATGGAATGCAACTAATCACTCATATGTTAGGTGGTAAAGTTGTTCCTGCTGG
CCAAGCTGGAAATCGTGAGTACGGTCAGTCAACTCTTCACCTCCGTGCCGATTCAAAATTGTTTGCAGGTACTCCTGAAG
AGCAACTTGTTTTGATGAGTCATGGTGATGCTGTCACAGAAATTCCAGAAGGCTTCCATCTTGTTGGTGACTCAAACGAC
TGCCCTTATGCGGCTATGGAAAATACTGAGAAAAACCTTTACGGTATTCAGTTCCATCCAGAAGTGAGACACTCTGTGTA
TGGGAATGATATTCTAAAAAACTTTGCAGTCTCTATCTGTGGGGCGCGTGGTGACTGGTCAATGGATAATTTCATTGAAA
TGGAAATCGCGAAAATTCGTGAAACTGTAGGTAATCGTAAAGTTCTCCTCGGACTTTCTGGAGGAGTAGATTCTTCAGTT
GTTGGCGTCCTTCTTCAAAAAGCTATTGGTGATCAATTAACTTGTATCTTTGTAGATCATGGACTTCTTCGTAAGGATGA
AGGAGACCAAGTTATGGGAATGCTTGGGGGCAAATTCGGCCTAAATATTATCCGTGTGGATGCTTCAAAACGTTTCCTTG
ATCTTCTTGCAGACGTTGAAGATCCTGAGAAAAAACGTAAAATCATCGGTAATGAATTTGTTTACGTTTTTGATGACGAG
GCCAGTAAATTAAAAGGTGTTGATTTCCTTGCTCAAGGAACGCTCTACACTGATATTATCGAATCAGGAACAGAAACTGC
CCAAACCATTAAATCTCACCATAATGTGGGAGGCCTTCCTGAAGACATGCAATTTGAATTGATTGAACCTTTAAACACTC
TCTTTAAAGATGAAGTTCGTGCTCTTGGAATTGCTCTTGGAATGCCTGAAGAAATTGTTTGGCGTCAACCCTTCCCTGGA
CCTGGTTTAGCTATTCGTGTTATGGGAGCTATTACTGAAGAGAAACTTGAAACTGTCCGCGAGTCAGATGCTATCCTTCG
TGAAGAAATCGCTAAGGCCGGTTTAGATCGTGACGTGTGGCAATACTTTACAGTTAACACAGGTGTCCGTTCTGTAGGTG
TCATGGGAGATGGTCGTACTTATGATTATACCATTGCCATTCGTGCCATTACTTCAATTGACGGTATGACAGCTGACTTT
GCTCAACTCCCTTGGGAGGTCTTGAAAAAAATCTCAACGCGTATCGTCAACGAGGTTGATCATGTCAATCGTATCGTCTA
CGACATCACCAGCAAACCACCTGCAACCGTTGAGTGGGAATAA

Protein sequence :
MTEISILNDVQKIIVLDYGSQYNQLIARRIREFGVFSELKSHKITAQELREINPIGIVLSGGPNSVYADNAFGIDPEIFE
LGIPILGICYGMQLITHMLGGKVVPAGQAGNREYGQSTLHLRADSKLFAGTPEEQLVLMSHGDAVTEIPEGFHLVGDSND
CPYAAMENTEKNLYGIQFHPEVRHSVYGNDILKNFAVSICGARGDWSMDNFIEMEIAKIRETVGNRKVLLGLSGGVDSSV
VGVLLQKAIGDQLTCIFVDHGLLRKDEGDQVMGMLGGKFGLNIIRVDASKRFLDLLADVEDPEKKRKIIGNEFVYVFDDE
ASKLKGVDFLAQGTLYTDIIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRALGIALGMPEEIVWRQPFPG
PGLAIRVMGAITEEKLETVRESDAILREEIAKAGLDRDVWQYFTVNTGVRSVGVMGDGRTYDYTIAIRAITSIDGMTADF
AQLPWEVLKKISTRIVNEVDHVNRIVYDITSKPPATVEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 2e-175 69
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 1e-175 69
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 1e-175 69
guaA NP_938969.1 GMP synthase Not tested Not named Protein 3e-119 52