Gene Information

Name : slo (GGS_1867)
Accession : YP_006860480.1
Strain : Streptococcus dysgalactiae RE378
Genome accession: NC_018712
Putative virulence/resistance : Virulence
Product : streptolysin O precursor
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2021016 - 2022740 bp
Length : 1725 bp
Strand : -
Note : similar to streptolysin O precursor(Thiol-activatedcytolysin)

DNA sequence :
ATGAAGGACATGTCTAATAAAAAAATATTTAAAAAATACAGTCGCGTCGCTGGGCTATTAACGGCAGCTCTTATCGTTGG
TAATCTTGTTACTGCTAATGCTGACTCGAACAAACAAAACACTGCCAATACAGAAACCACAACGACAAATGAACAACCAA
AACCAGAAAGTAGTGAGCTAACTACAGAAAAAGCAGGTCAGAAAATGGATGATATGCTTAACTCTAACGATATGATTAAG
CTTGCTCCCAAAGAAATGCCACTAGAATCTGCAGAAAAAGAAGAAAAAAACTCAGAAGACAATAAAAAAAGCGAAGAAGA
TCATACTGAAGAAATCAATGACAAGATTTATTCACTAAATTATAATGAGCTTGAAGTACTTGCTAAAAATGGTGAAACCA
TTGAAAACTTTGTTCCTAAAGAAGGCGTTAAGAAAGCTGACAAATTTATTGTCATTGAAAGAAAGAAAAAAAATATCAAC
ACTACACCGGTCGATATTTCCATCATTGACTCTGTCACTGATAGGACCTATCCAGCAGCCCTTCAGCTGGCTAATAAAGG
TTTTACCGAAAACAAACCAGACGCAGTAGTCACCAAGCGAAACCCACAAAAAATCCATATTGATTTACCAGGTATGGGAG
ACAAAGCAACGGTTGAGGTCAATGACCCTACCTATGCCAATGTTTCAACAGCTATTGATAATCTTGTTAACCAATGGCAT
GATAATTATTCTGGTGGTAATACGCTTCCTGCCAGAACACAATATACTGAATCAATGGTATATTCTAAATCACAGATTGA
AGCAGCTCTAAATGTTAATAGTAAAATCTTAGATGGTACTTTAGGCATTGATTTCAAGTCGATTTCAAAAGGTGAAAAGA
AGGTGATGATTGCAGCATACAAGCAAATTTTTTACACCGTATCAGCAAACCTTCCTAATAATCCTGCGGATGTGTTTGAT
AAATCAGTGACCTTTAAAGAGTTGCAACGAAAAGGTGTCAGCAATGAAGCCCCGCCACTCTTTGTGAGTAACGTAGCTTA
TGGTCGAACTGTTTTTGTCAAACTAGAAACAAGTTCTAAAAGTAATGATGTTGAAGCGGCCTTTAGTGCAGCTCTAAAAG
GAACAGATGTTAAAACTAATGGAAAATACTCTGATATTTTAGAAAATAGTTCATTTACAGCTGTCGTTTTAGGAGGAGAT
GCTGCAGAGCACAATAAGGTAGTCACAAAAGACTTTGATGTTATTAGAAACGTTATCAAAGATAATGCTACCTTCAGTAG
AAAAAACCCAGCTTATCCTATTTCATACACCAGTGTTTTCCTTAAAAATAATAAAATTGCGGGTGTCAATAACAGAAGTG
AATACGTTGAAACAACATCTACCGAGTACACGAGTGGAAAAATTAACCTGTCTCATCAAGGTGCCTATGTTGCTCAATAT
GAAATCCTTTGGGATGAAATCAATTATGATGACAAAGGAAAAGAAGTGATTACAAAACGACGTTGGGACAACAACTGGTA
TAGTAAGACATCACCATTTAGCACAGTTATCCCACTAGGAGCTAATTCACGAAATATCCGTATCATGGCTAGAGAGTGCA
CCGGCTTAGCTTGGGAATGGTGGCGAAAAGTGATCGACGAAAGAGATGTGAAACTGTCTAAAGAAATTAATGTCAACATC
TCAGGATCAACCTTGAGCCCATATGGTTCGATTACTTATAAGTAG

Protein sequence :
MKDMSNKKIFKKYSRVAGLLTAALIVGNLVTANADSNKQNTANTETTTTNEQPKPESSELTTEKAGQKMDDMLNSNDMIK
LAPKEMPLESAEKEEKNSEDNKKSEEDHTEEINDKIYSLNYNELEVLAKNGETIENFVPKEGVKKADKFIVIERKKKNIN
TTPVDISIIDSVTDRTYPAALQLANKGFTENKPDAVVTKRNPQKIHIDLPGMGDKATVEVNDPTYANVSTAIDNLVNQWH
DNYSGGNTLPARTQYTESMVYSKSQIEAALNVNSKILDGTLGIDFKSISKGEKKVMIAAYKQIFYTVSANLPNNPADVFD
KSVTFKELQRKGVSNEAPPLFVSNVAYGRTVFVKLETSSKSNDVEAAFSAALKGTDVKTNGKYSDILENSSFTAVVLGGD
AAEHNKVVTKDFDVIRNVIKDNATFSRKNPAYPISYTSVFLKNNKIAGVNNRSEYVETTSTEYTSGKINLSHQGAYVAQY
EILWDEINYDDKGKEVITKRRWDNNWYSKTSPFSTVIPLGANSRNIRIMARECTGLAWEWWRKVIDERDVKLSKEINVNI
SGSTLSPYGSITYK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
slo YP_281505.1 streptolysin O Virulence Not named Protein 0.0 99
hly AAA69525.1 listeriolysin O Virulence LIPI-1 Protein 6e-93 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
slo YP_006860480.1 streptolysin O precursor VFG0976 Protein 0.0 99
slo YP_006860480.1 streptolysin O precursor VFG2275 Protein 5e-150 67
slo YP_006860480.1 streptolysin O precursor VFG1363 Protein 2e-91 43
slo YP_006860480.1 streptolysin O precursor VFG0074 Protein 6e-93 43