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Name : topA (GGS_1236) Accession : YP_006859871.1 Strain : Streptococcus dysgalactiae RE378 Genome accession: NC_018712 Putative virulence/resistance : Unknown Product : DNA topoisomerase III Function : - COG functional category : - COG ID : - EC number : 5.99.1.2 Position : 1318692 - 1320398 bp Length : 1707 bp Strand : - Note : similar to conjugative transposon DNA topoisomerase [Clostridium difficile 630] DNA sequence : ATGAATTTAGTAATTGCTGAAAAGCCAAGTGTTGCAATTTCTATTGCAAAAGTGATCGGAGCAACAAAGAAGAAAGACGG ATATTATGAAGGAAACGGATATAAGGTAAGCTGGTGTGTTGGACATTTAATTAAAATGGCAAATCCGGAAAGCTATGATG AAAAGTATGCTAAGTGGAATATGGCGGATTTACCGATTATTCCAAAGGAATATAAGTATGAGATTGCAAAGTCCACAAAG AAACAATTTACGATTCTTAAAAAGCTGATGAATGATAAGGATATAGACATCGTGATAAATGCCTGCGATGCAGGGCGTGA AGGAGAAGCCATCTTCAGGCTTGTATATAATCAGGCAAATTGTAAAAAGAGAATGAAGCGTCTTTGGATTTCATCAATGG AAGATAGTGCCATAAAAGAGGGCTTTGATAACCTAAAAGATGGAAGTTCTTACGATAATCTATTTGAGTCTGCACAAGCA AGAGCAATAGCAGATTGGCTTGTGGGAATGAATTTAAGCAGACTGTATTCGTGTCTATACAAGCAAAATTACAGTGTGGG CAGAGTGCAGACACCTACCCTTGCAATGATTGTAAAAAGAGATGATGAGATAGCCAATTTCAAGAAAGAAAAATATTTTA CAGTGGAATTAAGCCTTAATGGCTTTACACTATCAACAGATAGAATTGATGATGAAATAACAGCGGAACAGCTCTTAAAT TTAGTAGGTGATAAGATAGAAATTACCGATGTTATTCAAAAGGAAAAGATAACAAAGCCTGAGCTGCCATTTGACCTGAC GACGCTTCAAAGAGAGTGCAATAAATATTTTGGATACTCAGCTAAGCAGACACTTGATTATGCTCAAAGTCTTTACGAAA AGAAACTGATTACCTATCCAAGAACAGACAGCAGATGCCTTACGGAAGATATGATTGTAAGTACGGTTAATAACATTTTA GGAAAGAATGATTTTGACACAGAGCGTATCAAGACGGTATTTAATTCTAAAAAGGTTACAGACCATCATGCGATTATACC GACAGCAAGCAGTATGAATGAGAACTTAACTTCCCTTCCGGAAAGTGAATTGAAGGTATATGAACTTATTTTAAATAAGC TACATGCAAGTGTAGGCTATCCTTTAATTGAGAATACAACGAAGATTGTGGCTGAATTTGATGGATTTGAATTTACAAGT AGTGGAAAGGTGATTGTAGATGATGGCTTTACCAAATACCTAAACGAATATGCGAAAAAGAAAAATGAAGATACAGTGCT TCCGGATGTAAAGATTGGTTATAGTCTTGATATTAAAGATAAAGAGATAAAAGAAAAATACACTCAACCAGCTAAGCATT TTACGGAAGATCTTCTCCTAAAGGCGATGGAGCTTGCAGGAAATGACGCATTGGAAAAAGGTGTAGAAGTTGAGCGAAAA GGACTTGGAACACCTGCAACAAGAGCAGGGATTATTGAAAATCTGATTTTCAAGGGATTTGTAGAAAGAGATAAAAAGAA CCTTATTGCTACACATAAGGGAATCAGCCTTGTAACGATTGTAGCCGATACTTTTAAATCAGCAGAAACAACAGCAAAGT GGGAAATGGAGTTATCGGATATTGCACAGGGGCAATCTTCAAAGGAAAACTTTTTAGAAGCGATTGAAAATGAGATAAAA GAAGTGGTTTCCACTTATACCAAGTAA Protein sequence : MNLVIAEKPSVAISIAKVIGATKKKDGYYEGNGYKVSWCVGHLIKMANPESYDEKYAKWNMADLPIIPKEYKYEIAKSTK KQFTILKKLMNDKDIDIVINACDAGREGEAIFRLVYNQANCKKRMKRLWISSMEDSAIKEGFDNLKDGSSYDNLFESAQA RAIADWLVGMNLSRLYSCLYKQNYSVGRVQTPTLAMIVKRDDEIANFKKEKYFTVELSLNGFTLSTDRIDDEITAEQLLN LVGDKIEITDVIQKEKITKPELPFDLTTLQRECNKYFGYSAKQTLDYAQSLYEKKLITYPRTDSRCLTEDMIVSTVNNIL GKNDFDTERIKTVFNSKKVTDHHAIIPTASSMNENLTSLPESELKVYELILNKLHASVGYPLIENTTKIVAEFDGFEFTS SGKVIVDDGFTKYLNEYAKKKNEDTVLPDVKIGYSLDIKDKEIKEKYTQPAKHFTEDLLLKAMELAGNDALEKGVEVERK GLGTPATRAGIIENLIFKGFVERDKKNLIATHKGISLVTIVADTFKSAETTAKWEMELSDIAQGQSSKENFLEAIENEIK EVVSTYTK |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| EFAU085_00720 | YP_008394244.1 | DNA topoisomerase III | Not tested | Not named | Protein | 2e-119 | 47 |
| topB-2 | NP_815968.1 | DNA topoisomerase III | Not tested | Not named | Protein | 2e-126 | 46 |
