Gene Information

Name : pyk (GGS_1048)
Accession : YP_006859689.1
Strain : Streptococcus dysgalactiae RE378
Genome accession: NC_018712
Putative virulence/resistance : Virulence
Product : putative pyruvate kinase
Function : -
COG functional category : -
COG ID : -
EC number : 2.7.1.40
Position : 1103899 - 1105401 bp
Length : 1503 bp
Strand : -
Note : similar to putative pyruvate kinase [Streptococcus pyogenes str. Manfredo]

DNA sequence :
ATGAATAAACGCGTAAAAATCGTTGCAACACTTGGTCCTGCGGTTGAAATCCGTGGTGGTAAAAAATACGGAGAAGATGG
CTACTGGGCTGGTCAACTTGATGTTGAAGAATCAGCAAAAAAAATCGCTGAATTAATTGAAGCTGGTGCGAATGTTTTCC
GTTTCAATTTCTCACACGGTGACCACAAAGAACAAGGTGACCGTATGGCAACTGTCCGCCTTGCAGAAGAAATTGCTCGT
CAAAAAGTTGGTTTCCTTTTGGATACTAAAGGTCCTGAAATGCGTACTGAATTATTTGCAGACGATGCTAAAGAGTTCAG
CTATGTTACTGGAGAAAAAATCCGTGTAGCGACTACACAAGGTATTCAATCAACTCGCGATGTTATTGCTTTGAACGTTG
CTGGTAGCCTTGACATCTACGATGAAGTAGAAGTAGGTCATACTATTCTTATCGATGATGGTAAGCTTGGTTTGAAAGTG
ATCGACAAAGATATCGCAACACGTCAATTTATTGTTGAAGTAGAAAACGACGGTATTATTGCTAAACAAAAAGGTGTTAA
TATCCCTAACACTAAAATTCCTTTCCCAGCACTTGCGGAACGCGACAATGCTGATATCCGTTTTGGTCTTGAACAAGGAC
TTAACTTTATTGCAATCTCATTTGTTCGTACAGCCAAAGACGTTGAGGAAGTTCGTGAAATCTGTCGCGAAACTGGTAAC
GACCATGTTCAATTATTTGCTAAGATTGAAAACCAACAAGGTATCGATAATCTTGATGAAATCATCGAAGCTGCTGATGG
TATCATGATTGCACGTGGCGACATGGGTATCGAAGTACCATTTGAAATGGTTCCAGTTTTCCAAAAAATGATTATCACTA
AAGTGAATGCAGCTGGTAAAGCAGTTATCACAGCAACAAACATGCTTGAAACAATGACTGAAAAACCACGTGCGACACGC
TCTGAAGTATCTGACGTCTTCAATGCTGTTATCGATGGTACTGATGCAACAATGCTTTCAGGAGAGTCAGCTAATGGTAA
ATACCCAGTTGAATCTGTTCGTACAATGGCGACTATTGATCGTAATGCACAAACTCTTCTTAACGAATATGGTCGTTTAG
ATTCATCTGCATTCCCACGTACAAATAAAACTGATGTAATTGCTTCAGCGGTTAAAGATGCAACTCATTCAATGGACATC
AAACTTGTGGTTACAATTACCGAAACTGGTAATACTGCACGTGCGATTTCTAAATTCCGTCCAGATGCGGACATCTTAGC
TGTAACATTTGATGAAAAAGTACAACGTGCATTGATGATTAACTGGGGTGTTATTCCAGTTCTTGCTGAAAAACCTGCAT
CTACTGATGACATGTTTGAAGTAGCAGAACGTGTGGCTCTTAAAACTGGTTTGGTTCAATCTGGTGATAACATTGTTATC
GTTGCAGGTGTTCCAGTTGGTACTGGTGGAACAAACACAATGCGTGTTCGTACTGTAAAATAA

Protein sequence :
MNKRVKIVATLGPAVEIRGGKKYGEDGYWAGQLDVEESAKKIAELIEAGANVFRFNFSHGDHKEQGDRMATVRLAEEIAR
QKVGFLLDTKGPEMRTELFADDAKEFSYVTGEKIRVATTQGIQSTRDVIALNVAGSLDIYDEVEVGHTILIDDGKLGLKV
IDKDIATRQFIVEVENDGIIAKQKGVNIPNTKIPFPALAERDNADIRFGLEQGLNFIAISFVRTAKDVEEVREICRETGN
DHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMGIEVPFEMVPVFQKMIITKVNAAGKAVITATNMLETMTEKPRATR
SEVSDVFNAVIDGTDATMLSGESANGKYPVESVRTMATIDRNAQTLLNEYGRLDSSAFPRTNKTDVIASAVKDATHSMDI
KLVVTITETGNTARAISKFRPDADILAVTFDEKVQRALMINWGVIPVLAEKPASTDDMFEVAERVALKTGLVQSGDNIVI
VAGVPVGTGGTNTMRVRTVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 6e-81 43
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 3e-81 43
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 3e-81 43
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 2e-81 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pyk YP_006859689.1 putative pyruvate kinase VFG0479 Protein 1e-81 43