Gene Information

Name : PAC1_01460 (PAC1_01460)
Accession : YP_006850301.1
Strain : Propionibacterium acnes C1
Genome accession: NC_018707
Putative virulence/resistance : Virulence
Product : negative regulator of genetic competence ClpC/MecB
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 333642 - 336176 bp
Length : 2535 bp
Strand : +
Note : COG0542 ATPases with chaperone activity, ATP-binding subunit

DNA sequence :
ATGTTCGAACGGTTCACCGATCGGGCCCGCCGGGTCGTCGTCCTGGCCCAGGATGAGGCCAAGGCCCTGAACCACAATTA
CATTGGCACTGAGCACCTGCTGCTCGGGCTCATTAGCGAGGGCGAGGGAGTCGCTGCCAAGGCTCTCGAGTCCCTTGACA
TTTCACTGGAGGCTGTTCGCGCCCAGGTGGAGGAGATTATTGGTCACGGCACTTCGACGCCGACGGGCCATATTCCCTTT
ACCCCGCGTGCCAAGAAGGTTCTTGAGCTGAGCCTGCGCGAAGCCCTCCAGATGAATCATTCGTACATTGGCACCGAGCA
CATTCTGCTTGGCCTTATCCGGGAGGGAGAAGGCGTCGCTGCTCAGGTACTGATCCGGCTGGGTGCTGACCTCAACACGG
TGCGCAATAGCGTCTTGCAACTGTTGCAGGGATATCAGGGCGACGAGCGTCAGGCCGCCACTTCCGGTGCCCCCGAGGCC
GGACCGCAGCAGTCCTCGGCGACGATTCTTGACCAATTCGGTCGCAACCTTACCGAGGCCGCCCGCGACGGCGAGCTCGA
CCCGGTTATCGGGCGTGAGAGGGAAATCGAACGAGTCATGGTGGTGCTGAGCCGGCGCACCAAGAATAACCCGGTTCTTA
TTGGTGAGCCTGGCGTCGGTAAGTCTGCTTGTGTCGAGGGCCTGGCTCAGGCCATCGTGCGTGGAGACGTTCCCGAGACT
CTGCGTGACAAGAAGATTTACTCCCTGGACCTTGGCTCCATGGTTGCGGGATCGCGTTACCGCGGTGATTTCGAGGAGAG
GATGAAGAAGGTCCTCAAGGAGATAAAAAATCGCGGGGACATCATCCTGTTCATCGACGAGATCCACACCCTTGTCGGCG
CCGGTGCCGCTGAAGGGGCAATCGACGCTGCCAGCATGCTCAAGCCGATGCTGGCTCGCGGCGAGCTGCAGACTATCGGT
GCGACGACCCTTGATGAGTACCGTAAGTACATCGAGAAGGACGCCGCCCTGGAGCGTCGCTTCCAGCCGATCCAGGTAGA
CGAGCCCTCGATCCCCCTGGCCATCGAGATCCTTAAGGGTCTGCGCGACCGGTACGAGGCCCACCACAAGATCACCATCA
CCGACGAGGCAATCACCTCCGCAGCGAATCTTGCGTCCCGTTACATCCAAGACCGCTTCCTGCCAGACAAGGCCATCGAT
CTCATTGACGAGGCCGGTGCCCGGATGAACATCCGCCGCATGACGGCCCCGCCGGATCTGCGCGAGTTCGACGAGCGGAT
TGCTCGTGTGCGAGTGGAGAAAGAGGCCGCCATCGACGCCCAGGATTTCGAGCGTGCTGCTGGGCTGCGCGACGACGAAA
AGAAACTTCTCGCCGAGCGTGAGGCCAAGGAGGAGGAGTGGAAGCAGGGTGACGAGTCGGTGCCAGCCGTGGTCGGCCCT
GATGAGATCGCCGAGGTGCTCTCTGGAGCTACCGGAATTCCGGTCTTCAAGCTCACGGAGGAGGAATCCCAGCGTCTGCT
CCACATGGAGGACGAGATCGGCAAGCGTTACGTCGGCCAGGAGGACGCCGTTAAGGCCCTGTGCCGCTCTATCCGACGTA
CCCGTGCCGGCCTCAAGGACCCGAAGCGTCCGGCAGGTTCGTTCATTTTTGCTGGCCCGTCGGGTGTTGGTAAGACCGAG
CTCACCAAGGCGCTCACCGAGTTCCTCTTTGGCGACGAGGACGCCCTCATCACCCTCGACATGAGCGAGTACTCCGAGAA
ACACACCGCTTCGCGGATGTTTGGGTCCCCGCCTGGATTCGTCGGGTACGAGGAGGGCGGCCAGCTCACCGAGAAGGTGC
GCCGCAAGCCGTTCAGCGTCATTCTCTTTGACGAGATTGAAAAGGCCCACCCCGATATCTTCAACTCTCTGTTGCAGATT
CTTGACGAGGGACGTCTTACTGACGCCCAGGGCCGTGTAGTGGACTTTAAGAACACCGTCATTGTGCTGACGACCAACCT
TGGCACCCGCGACATTTCCAAATCAGTCAATCTCGGCTTTTCCAAGGCCGACGACGTCGAGTCTAGCTACGAGAAGATGA
AGGCCAAGGTTACCGAGGAGCTCAAGGGACACTTCCGTCCCGAGTTCCTCAACCGCCTTGACGAGATCATCGTCTTCCAT
CAGCTCACCCAGCCCGACATCCTACGGATTGTCGACCTCATGGTGGGGCAACTGGAGGATCGTCTGGCCGACAAGGACAT
GGGTATCGAGGTCACTCCGGCTGCCAAGGAACTGCTGTCCACGCGTGGTTTCGACCCGCTGCTCGGTGCTCGTCCGCTGC
GCCGGACGATCCAGCGCGACATCGAGGACGTCCTAGCCGAGAAGATCCTCTTCGGGGAGGTCAAACCTGGTCAGATCGTG
GTGGTCGATGCTGCCCCGGAGGGTTCCGAGGAGCCGTTCGTCTTCACCGGCACGGAGCGCTCAGAGCTGCCTGACGAGGT
TCCTCCTGAGCTCACCTCTTCGGCAGGGGAAAATAACAGGGGGCAGCAGGGCTGA

Protein sequence :
MFERFTDRARRVVVLAQDEAKALNHNYIGTEHLLLGLISEGEGVAAKALESLDISLEAVRAQVEEIIGHGTSTPTGHIPF
TPRAKKVLELSLREALQMNHSYIGTEHILLGLIREGEGVAAQVLIRLGADLNTVRNSVLQLLQGYQGDERQAATSGAPEA
GPQQSSATILDQFGRNLTEAARDGELDPVIGREREIERVMVVLSRRTKNNPVLIGEPGVGKSACVEGLAQAIVRGDVPET
LRDKKIYSLDLGSMVAGSRYRGDFEERMKKVLKEIKNRGDIILFIDEIHTLVGAGAAEGAIDAASMLKPMLARGELQTIG
ATTLDEYRKYIEKDAALERRFQPIQVDEPSIPLAIEILKGLRDRYEAHHKITITDEAITSAANLASRYIQDRFLPDKAID
LIDEAGARMNIRRMTAPPDLREFDERIARVRVEKEAAIDAQDFERAAGLRDDEKKLLAEREAKEEEWKQGDESVPAVVGP
DEIAEVLSGATGIPVFKLTEEESQRLLHMEDEIGKRYVGQEDAVKALCRSIRRTRAGLKDPKRPAGSFIFAGPSGVGKTE
LTKALTEFLFGDEDALITLDMSEYSEKHTASRMFGSPPGFVGYEEGGQLTEKVRRKPFSVILFDEIEKAHPDIFNSLLQI
LDEGRLTDAQGRVVDFKNTVIVLTTNLGTRDISKSVNLGFSKADDVESSYEKMKAKVTEELKGHFRPEFLNRLDEIIVFH
QLTQPDILRIVDLMVGQLEDRLADKDMGIEVTPAAKELLSTRGFDPLLGARPLRRTIQRDIEDVLAEKILFGEVKPGQIV
VVDAAPEGSEEPFVFTGTERSELPDEVPPELTSSAGENNRGQQG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 71

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
PAC1_01460 YP_006850301.1 negative regulator of genetic competence ClpC/MecB VFG0079 Protein 0.0 58
PAC1_01460 YP_006850301.1 negative regulator of genetic competence ClpC/MecB VFG0080 Protein 4e-152 51