Gene Information

Name : cmlA (BN406_02486)
Accession : YP_006841357.1
Strain : Sinorhizobium meliloti Rm41
Genome accession: NC_018700
Putative virulence/resistance : Resistance
Product : chloramphenicol resistance protein
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2555929 - 2557128 bp
Length : 1200 bp
Strand : +
Note : -

DNA sequence :
ATGCCTACAAAAAACCATGTCTGGCGCTATTCGCTGCCGGCAGCGCTGCTGCTGATGGCGCCCTTCGATATCCTCGCCTC
TCTGGCCATGGATATTTATCTCCCGATCGTTCCTGCGATGCCCGGTATTCTCGGCACCAGCCCTGCCGTGGTTCAGCTCA
CGCTGAGCCTCTATATGGTTATGCTCGGCCTCGGCCAGATTGTCTTCGGGCCCGTCTCCGACCGCATCGGACGACGGCCA
GTCCTGATCGGCGGAGCGATGCTGTTCGCCGCCGCATCGTTCTGCCTCGCGGCTTCCTCCAGCGCCATCCCTTTCGTCGC
CTTCCGCTTCCTCCAGGCGGTTGGCGCATCTGCGGCTCTGGTGGCCACCTTTGCAACGATCCGGGATGTATATGCCGACC
GCCCGGAAGGCGTGGTCATCTACAGCCTGTTCAGTTCCATTCTGGCATTCGTTCCCGCTCTGGGGCCGATAGCCGGTGCC
ATGCTGGCGGAGAGGTTCGGATGGCGCTCGATCTTCGTTACGCTGGGTGCATTAGCCATAATCGCGCTGCTGCAGGCACT
GCCTCGCTGGCATGAATCCCGCCCTTCGGCGGCAGCGCTGTCGCGGCACGCATTCGGCCCCCTTTTCCGCAGCCTCGCCT
TCTGGACCTATACCCTCGGCTTCAGCGCCGCCATGGGCACGTTCTTCGTGTTCTTTTCCACCTCGCCGCGCGTGCTGATC
GACAAGGCAGGATATTCGGAGCTGCAGTTCAGCCTCGCCTTTGCAACTGTAGCAATCGTGATGATCATCACGGCGCGCTT
TGCCGAGCGGTTCGTCTCCCGATGGGGAACTTCGGGCAGCCTCCTGCGGGGCATGTGCATGTTGCTTCTCGGGGCAGCGC
TCCTGATTGCCGGGGAAACGTTCGGCGTCCCTTCGTCCTGGACCTTCGTCATGCCGATGTGGGTGATGGCGGTCGGCATC
GTCTTCACCGTATCGGTGACCGCAAACGGCGCTCTCGAGGATTTTGGAGACATGGCGGGTTCGGCGGTCGCAGTCTATTT
CTGCGTCCAAAGCCTCATCGTCGGGACGGCGGGGACACTGCTCGTGATCGGACTGCCCGGCGACAGCGCGTGGCCGCTTG
TCGTCTATGCCTCGATTATGGCCGGCGTTGTGCTGATCGCGCGCCGGCAGTTGCATTCCAGAAGGCATGTGCAGGCATGA

Protein sequence :
MPTKNHVWRYSLPAALLLMAPFDILASLAMDIYLPIVPAMPGILGTSPAVVQLTLSLYMVMLGLGQIVFGPVSDRIGRRP
VLIGGAMLFAAASFCLAASSSAIPFVAFRFLQAVGASAALVATFATIRDVYADRPEGVVIYSLFSSILAFVPALGPIAGA
MLAERFGWRSIFVTLGALAIIALLQALPRWHESRPSAAALSRHAFGPLFRSLAFWTYTLGFSAAMGTFFVFFSTSPRVLI
DKAGYSELQFSLAFATVAIVMIITARFAERFVSRWGTSGSLLRGMCMLLLGAALLIAGETFGVPSSWTFVMPMWVMAVGI
VFTVSVTANGALEDFGDMAGSAVAVYFCVQSLIVGTAGTLLVIGLPGDSAWPLVVYASIMAGVVLIARRQLHSRRHVQA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
floR YP_005176183.1 florfenicol / chloramphenicol efflux protein Not tested ICEPmu1 Protein 3e-106 69
flo AAK02049.1 chloramphenicol and florfenicol resistance protein Not tested SGI1 Protein 1e-107 68
floRc AGK06972.1 chloramphenicol and florfenicol resistance protein Not tested SGI1 Protein 1e-107 68
floRc AGK07102.1 chloramphenicol and florfenicol resistance protein Not tested SGI1 Protein 1e-107 68
cmlA9 ABZ01840.1 CmlA9 chloramphenicol efflux protein Not tested SGI2 Protein 2e-107 67
cmlA CAJ77032.1 chloramphenicol and florfenicol resistance protein Not tested AbaR1 Protein 2e-107 67
cml(A)5 ACY75522.1 CmLA(5) Not tested Tn6060 Protein 6e-80 50
cmlA5 CAJ77046.1 Chloramphenicol resistance protein Not tested AbaR1 Protein 3e-79 50

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
cmlA YP_006841357.1 chloramphenicol resistance protein DQ522237.1.gene4.p01 Protein 3e-80 50
cmlA YP_006841357.1 chloramphenicol resistance protein NC_010410.6003586.p0 Protein 3e-80 50
cmlA YP_006841357.1 chloramphenicol resistance protein AF156486.gene.p01 Protein 3e-79 50
cmlA YP_006841357.1 chloramphenicol resistance protein DQ984668.gene.p01 Protein 3e-80 50
cmlA YP_006841357.1 chloramphenicol resistance protein AF294653.1.gene4.p01 Protein 2e-80 50