Gene Information

Name : ispE (MC28_4614)
Accession : YP_006831435.1
Strain : Bacillus thuringiensis MC28
Genome accession: NC_018693
Putative virulence/resistance : Virulence
Product : 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase
Function : -
COG functional category : -
COG ID : -
EC number : 2.7.1.148
Position : 4485485 - 4486297 bp
Length : 813 bp
Strand : -
Note : -

DNA sequence : 
ATGGCAACTTTAGCAGTTGATTCGGTATCTGTTGGCTATAATGAAGGATTAATTATTGATGGATTAACAGTTGAAATTCC
GGAAGGAAAAATTACAACGATTATTGGACCAAATGGTTGTGGGAAATCCACATTATTAAAAACGGCTTCTCGTATTTTGA
AGGCGAAAAAAGGTACTGTTTATCTTGATGGAAAAGCAATTGAGAAACAGCCAACGAAAGAAATCGCAAAGAAAATGGCG
ATCTTACCACAAACTGCAGAAGTGCCAACAGGCCTTACTGTGTTTGAACTTGTTTCATATGGACGTTTTCCTCATCAAAA
AGGATTTGGAACATTGAAAGAAGAAGATTATCGCTACATTCATTGGGCACTTGAAGTGACGGGAATGACAGAGTTCGCAA
ATCGTTCAGCAGAAGCCTTATCAGGTGGTCAACGTCAACGGGTATGGATTGCGATGGCTCTTGCACAAGGAACAGATTTA
CTTGTATTAGATGAACCAACGACATATTTAGATATGGCACATCAACTTGAAGTATTAAACTTACTGAAGAAATTGAACCA
AGAAGAAGGTAGGACAATTGTGATGGTTATTCACGATTTAAATCATGCTTCTCGTTTCTCTGATCATATGATTGCATTAA
AAGCAGGTAAGTTAATGAAACAAGGAACGCCAGATGAGGTTATGACAAGTGAAACACTTCGTAACGTGTTTGAGATTGAA
GCGCAAATCGTTCCATGTCCAGTAAACTGTAAACCGATTTGTTTAACATATGATTTAGCGATGATTAGTAATCAATTGCG
TAAAAAAGCATAA

Protein sequence : 
MATLAVDSVSVGYNEGLIIDGLTVEIPEGKITTIIGPNGCGKSTLLKTASRILKAKKGTVYLDGKAIEKQPTKEIAKKMA
ILPQTAEVPTGLTVFELVSYGRFPHQKGFGTLKEEDYRYIHWALEVTGMTEFANRSAEALSGGQRQRVWIAMALAQGTDL
LVLDEPTTYLDMAHQLEVLNLLKKLNQEEGRTIVMVIHDLNHASRFSDHMIALKAGKLMKQGTPDEVMTSETLRNVFEIE
AQIVPCPVNCKPICLTYDLAMISNQLRKKA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
DIP0585 NP_938961.1 iron ABC transporter ATP-binding protein Virulence Not named Protein 2e-56 47
fecE AAL08451.1 ATP-binding protein FecE Virulence SRL Protein 3e-54 46
iusE YP_005143742.1 iron ABC transporter ATP-binding protein Virulence Not named Protein 1e-56 46
SPN23F_09560 YP_002510939.1 ferric siderophore ABC transporter ATP-binding protein Virulence PPI-1 Protein 2e-55 46
SP_1035 NP_345510.1 iron-compound ABC transporter ATP-binding protein Not tested PPI-1 Protein 2e-55 46
ciuD YP_005681255.1 Iron ABC transporter ATP-binding protein Virulence PiCp 4 Protein 2e-57 45
ciuD YP_005683346.1 Iron ABC transporter ATP-binding protein Virulence PiCp 4 Protein 2e-57 45
ciuD YP_003783391.1 iron ABC transporter ATP-binding protein Virulence PiCp 4 Protein 2e-57 45
ciuD YP_005685432.1 Iron ABC transporter ATP-binding protein Virulence PiCp 4 Protein 2e-57 45
fagC YP_005680307.1 ATP binding cytoplasmic membrane protein Not tested PiCp 1 Protein 1e-54 45
fagC YP_003782430.1 ABC transporter ATP-binding protein Not tested PiCp 1 Protein 1e-54 45
fagC YP_005682397.1 ATP binding cytoplasmic membrane protein Virulence PiCp 1 Protein 1e-54 45
fagC YP_005684488.1 ATP binding cytoplasmic membrane protein Not tested PiCp 1 Protein 1e-54 45

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ispE YP_006831435.1 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase BAC0164 Protein 2e-54 46

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ispE YP_006831435.1 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase VFG0925 Protein 2e-55 47
ispE YP_006831435.1 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase VFG1042 Protein 2e-54 46