Gene Information

Name : lysS (ASU2_04630)
Accession : YP_006817303.1
Strain : Actinobacillus suis H91-0380
Genome accession: NC_018690
Putative virulence/resistance : Virulence
Product : lysyl-tRNA ligase
Function : -
COG functional category : -
COG ID : -
EC number : 6.1.1.6
Position : 1009390 - 1010892 bp
Length : 1503 bp
Strand : -
Note : COG1190 Lysyl-tRNA synthetase (class II)

DNA sequence :
ATGTCTGAAGTTGAAAACCAAGAATTAGATCTTAATGGTGAAATGTTAGCTCGCCGTGAGAAATTAGCAAAATTACGTGA
ACAAGGTAATCCGTTCCCGAATACTTTCCGTCGTGATGCTTATGCAGAAAAATTACACGCACAATACGATGAAGTAGAGG
GTGAAGCGTTAAAAGAACAAGATATTCAAGTGAAAGTTGCCGGCCGTATTATGCTTAAACGTGTAATGGGTAAAGCGTCT
TTCTTTACCATTCAAGATGTAAGCGGTCAAATCCAGCTTTATGTTGCACGTGATAACCTTGCTGAAGGCGTGTATGCGGA
TAAAGTCAGTATGTGGGATTTAGGCGATATCGTTGGTGTTGCCGGTACGCTTTTCAAAACGAAAACAGGTGAATTAACCG
TTCGTTGTTCAGAAGTAGAGTTATTAACTAAATCACTTCGTCCGTTACCAAACAAAGTACAAGGTTTAACCGACCAAGAA
ACACGTTATCGTCAACGTTATTTAGACTTAATTTCTAATGAAGAATCTCGCCGTACGTTTATGATTCGTTCAAAAGTGGT
TTCAGGCATTCGTCAATTCTTCTTAGAGAAAGACTTTATTGAAGTTGAAACACCAATGTTACAAGTGATTCCGGGCGGTG
CGGCAGCAAAACCGTTTATCACTCACCACAATGCGTTAGACGTAGATATGTATTTACGTATTGCGCCTGAGCTTTACTTA
AAACGTTTAGTAGTTGGTGGTTTTGAGCGTGTATTCGAATTAAACCGTAACTTCCGTAACGAAGGTGTTTCAGTGCGTCA
TAACCCTGAATTCACCATGATCGAATACTATCAAGCGTATGCGGATTACCACGATTTAATGGATAACACCGAAGAATTAT
TACGTAAATTAGCGATTGATATTCTTGGCACGACAACCGTTCCTTACGGTGAATACGTGTTCGATTTCGGTAAACCATTC
GAGCGTATCACCATGCACGATGCGATCGTAAAATACGGTAACGGCATTACACGTGAGGATTTAGATAGCTTCGAAAAATC
AGTAGAAATTGCTAAAGGTTTAGGTATTGAAATCCAAAAATCTTGGGGCTTAGGCTCAGTAGTAAATGCCATTTTCGAAG
AAGTTGCGGAACACCAATTAATTCAACCGACTTTCTTAATGGCACACCCAGCGGAAATTTCACCGCTTGCACGCCGTAAT
GATGAAAATCCAGAAGTAACAGATCGCTTTGAGTTATTTATCGGTGGTCGTGAAATCGGTAACGGTTTCTCAGAACTGAA
TGATGCGGAAGACCAAGCAGAACGCTTTGATGCTCAGGTTGCAGCGAAAGATGCGGGCGATGACGAAGCAATGTTTAAAG
ATGAAGACTTCGTGGTAGCATTAGAGCACGGCTTACCGCCGACAGCTGGTGAAGGTTTAGGTATCGACCGTTTAGCAATG
ATTTTTGCAAACGCACCGTCAATTCGTGATGTGATCTTATTCCCTGCAATGCGCCAGAAATAA

Protein sequence :
MSEVENQELDLNGEMLARREKLAKLREQGNPFPNTFRRDAYAEKLHAQYDEVEGEALKEQDIQVKVAGRIMLKRVMGKAS
FFTIQDVSGQIQLYVARDNLAEGVYADKVSMWDLGDIVGVAGTLFKTKTGELTVRCSEVELLTKSLRPLPNKVQGLTDQE
TRYRQRYLDLISNEESRRTFMIRSKVVSGIRQFFLEKDFIEVETPMLQVIPGGAAAKPFITHHNALDVDMYLRIAPELYL
KRLVVGGFERVFELNRNFRNEGVSVRHNPEFTMIEYYQAYADYHDLMDNTEELLRKLAIDILGTTTVPYGEYVFDFGKPF
ERITMHDAIVKYGNGITREDLDSFEKSVEIAKGLGIEIQKSWGLGSVVNAIFEEVAEHQLIQPTFLMAHPAEISPLARRN
DENPEVTDRFELFIGGREIGNGFSELNDAEDQAERFDAQVAAKDAGDDEAMFKDEDFVVALEHGLPPTAGEGLGIDRLAM
IFANAPSIRDVILFPAMRQK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 5e-150 62
lysS YP_005163386.1 lysyl-tRNA synthetase Not tested Not named Protein 3e-87 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_006817303.1 lysyl-tRNA ligase VFG1668 Protein 3e-150 62