Gene Information

Name : guaA (ASU2_04090)
Accession : YP_006817195.1
Strain : Actinobacillus suis H91-0380
Genome accession: NC_018690
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : -
COG ID : -
EC number : 6.3.5.2
Position : 881405 - 882976 bp
Length : 1572 bp
Strand : +
Note : COG0518 GMP synthase - Glutamine amidotransferase domain

DNA sequence :
ATGAACAACATTCACAATCATAAAATTTTAATTTTGGACTTCGGTTCACAATACACGCAATTAATCGCACGTCGTGTGCG
TGAGATTGGGGTTTACTGCGAGCTTTGGGCGTGGGACGTTACCGAAGAACAAATCCGTGAATTTAACCCGACCGGGATTA
TTCTTTCAGGTGGTCCTGAAAGTACCACTGAAGAAAATAGCCCTCGTGCGCCGGAATACGTATTTAACGCAGGCGTGCCA
GTACTTGGTATTTGCTACGGTATGCAAACCATGGCGATGCAATTAGGCGGTTTAACTGAAACTTCTGATCATCGTGAATT
CGGCTATGCTTCAGTTGATTTACAAGCGACCGATGCGTTATTTGCAAAATTAAACGATAATTTGACCGCTTCCGAGCCGA
AATTAGATGTTTGGATGAGCCACGGCGATAAAGTAACTCGTTTACCGCAAGGTTTCCAAATCACTGGTGTCACACCTACT
TGCCCGATTGCTGCAATGTCAGACGAAAGCCGCCGTTTTTACGGTGTACAATTCCACCCGGAAGTAACCCATACCAAAAG
CGGTTTAGAGTTATTAACCAACTTCGTAGTAGGTATTTGTGGCTGTGAATGTAAATGGACAGCAGAAAACATTATCGAAG
ACGCTGTGGCTCGCATTAAAGAGCAAGTGGGCGATGATGAAGTTATTTTAGGCTTATCAGGTGGCGTGGATTCATCAGTA
ACTGCACTTCTTCTACATCGTGCAATCGGCAAAAACTTACACTGCGTATTCGTGGATAACGGTTTACTTCGTTTAAATGA
AGGCGATCAAGTGATGGAAATGTTCGGCGATAAATTCGGTTTAAACATCATTCGAGTAAATGCTGAGGATCGTTTCTTAG
ATGCATTAAAAGGCATTGATGAGCCGGAAGCAAAACGTAAAACCATTGGTAAAGTGTTTGTCGATGTATTCGATGATGAA
TCGAAAAAACTGACCTCAGTGAAATGGTTAGCACAAGGTACTATTTACCCTGACGTGATCGAATCGGCAGCAAGCAAAAC
CGGTAAAGCACACGTAATTAAATCTCACCACAACGTAGGCGGCTTACCAGATTATATGAAACTCGGTTTAGTGGAACCGT
TACGAGAATTATTCAAAGATGAAGTGCGTAAAATCGGTTTAGCACTTGGTTTACCGGCAGAAATGTTAAATCGCCACCCA
TTCCCAGGCCCAGGCTTAGGCGTGCGAGTATTAGGTGAAATCAAGAAAGAATACTGTGATTTACTGCGTAAAGCAGATGC
AATCTTTATCGAAGAGCTATACAAAGCAGATTGGTATTACAAAGTAAGCCAAGCGTTCACCGTATTCCTTCCGGTGAAAT
CGGTGGGTGTAATGGGCGATGGACGTAAATACGACTGGGTTGTTTCACTCCGTGCAGTGGAAACTATCGACTTTATGACC
GCACATTGGGCGCATTTACCATACGATTTACTTGGTAAAATCTCAAACCGTATTATCAATGAAGTAAACGGCATTTCCCG
CGTGGTATATGACGTTTCAGGCAAACCACCTGCAACGATTGAGTGGGAGTAA

Protein sequence :
MNNIHNHKILILDFGSQYTQLIARRVREIGVYCELWAWDVTEEQIREFNPTGIILSGGPESTTEENSPRAPEYVFNAGVP
VLGICYGMQTMAMQLGGLTETSDHREFGYASVDLQATDALFAKLNDNLTASEPKLDVWMSHGDKVTRLPQGFQITGVTPT
CPIAAMSDESRRFYGVQFHPEVTHTKSGLELLTNFVVGICGCECKWTAENIIEDAVARIKEQVGDDEVILGLSGGVDSSV
TALLLHRAIGKNLHCVFVDNGLLRLNEGDQVMEMFGDKFGLNIIRVNAEDRFLDALKGIDEPEAKRKTIGKVFVDVFDDE
SKKLTSVKWLAQGTIYPDVIESAASKTGKAHVIKSHHNVGGLPDYMKLGLVEPLRELFKDEVRKIGLALGLPAEMLNRHP
FPGPGLGVRVLGEIKKEYCDLLRKADAIFIEELYKADWYYKVSQAFTVFLPVKSVGVMGDGRKYDWVVSLRAVETIDFMT
AHWAHLPYDLLGKISNRIINEVNGISRVVYDVSGKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 1e-130 54
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 8e-131 54
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 6e-131 54
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-109 47