Gene Information

Name : ASU2_03875 (ASU2_03875)
Accession : YP_006817152.1
Strain : Actinobacillus suis H91-0380
Genome accession: NC_018690
Putative virulence/resistance : Unknown
Product : putative type I site-specific restriction-modification system, restriction subunit
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 829592 - 832732 bp
Length : 3141 bp
Strand : -
Note : COG0610 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases

DNA sequence :
ATGCACATCAACGAAAACACAATAGAGCAAGCCTGTATTCAGGCATTACAAGGCTTGGGGTGGGCTTATACCTTTGGTTC
GGAGATTGAGCGGGAGCGAGCTGAAGAGGTGGTGCTGAAATCGGTGTTGGCGAATGCGATAACAAGGCTAAATCCGCAGT
TACCGAGTAATGTGGTCAATGACGTGGTGGCGTTGGTGTGTAAGGGCGATATTACCGATTTAACTGAGCGTAATCAGCAA
TTTTACCGCTTGTTGCGTGAAGGCGTGCAGGTGGAGTATCGTGAAAATGATGAGCAGAAAATCGACATTGTTCGTTTGAT
TGATTTTCAAAATGTTCACAACAACCAGTTTGATGTGGTAAATCAATTTACCATTAAGGGGGTGAAAGGCAACCGCCGCC
CTGATGTGATTTGCTTTGTGAATGGTTTGCCGTTGGTGGTGTTTGAGTTGAAAAATCCGCTTACAGAATCAGCCGATTTG
CAACAGGCATTTCAGCAGTTCCAAACTTATAAAGCGGAAATTAGCGATCTCTTTGTTTTCAACCAAGCCCTTGTGATTAG
TGACGGTACGCACGCTCGCATTGGTTCTTTAACCGCCAATTTTGACCGCTTTACACCGTGGCGAGTGGTGGACGAAAAAG
CTAAACAGCGAGTGCCGTTTGAGAATGAATTGGCGGGGCTGGTGCAAGGCTTGATGTCGCCTGAAAATTTACTCAATTAT
GTGCAGAATTTCGTGCTATTTGAGCGTTCGGAAAGCGGTCTGTTAATCAAAAAAATTGCCGCTTATCATCAATTCTATGG
CGTGAATGAGGCAGTGGAGTCCACGTTGCTTGCCGCAAGCGAGCAAGGCGATCGCAAAATTGGGGTAATGTGGCATACGC
AAGGTTCGGGCAAATCCATTTCGATGCTGTTCTATGCGGCAAAATTGCAAGCCGAGCCAAGCTTACGCAACCCAACCATT
GTAGTGGTAACCGACCGTAACGACTTAGACGGTCAGCTATTTGCGACCTTTTCAGCGGGTAAAGATCTTATTCGCCAAAC
ACCCATTCAAGCAGACGGACGAGAAGCATTGCGAACCGAGCTTGCCAAGCGTGAAACAGGCGGCATTATTTTTACCACCA
TTCAAAAATTTGGCTTGCACGAGGGCGAAAATCAGCACCCGATTTTGAATGATCGCCACAACATTATCGTCATCAGCGAT
GAGGCTCATCGTTCGCAATATGGTTTTAGCCAACATTTAGCTATGGGAACACAATCCGCTACTTACCGAGTGGGCTATGC
CAAACATTTACGAAATGCGTTGCCGAATGCCTCGTTTATTGGCTTTACTGGTACGCCAATTTCCCTTGAAGATAAAGATA
CTCAAGCAGTGTTTGGGCGTTATGTGTCGATTTACGACATTCAAGATGCGGTGGAAGACGGTGCAACCGTGCCGATTGTG
TATGAGGCTCGCCAAATTCCGATTAACGAGAGCCAAGATTTCAAAAATGCGGTGCGTGAGGCGGACGATTTATTTTCGGA
CGATGAGCAAAGTTACAGTTTCCGCTTGCGTGAAAAGCTAATAGGGGCGGATACACGGCTCACAAAATTAGCGGAAGATT
TGGTAAAACATTTTGAAAATCGCACCGCTTTAATGGACGGTAAGGCGATGATTGTGGCAATGAGCCGTCAAATTTGTGTG
GTGTTGTATGACAAAATCATTGCCCTTCGCCCTGAATGGCATAGCGATAATCTCAACGAAGGGGCGATTAAAATTGTGAT
GACAGGCTCAGCAAGTGATCCTGACCATTTTCAACCGCACATTTATGGCAATCAAGAGAAGAAAAGCCTCGAAAAACGTT
TTAAAGATCCGAGTGATCCGTTCAAACTTGTGATTGTGCGAGATATGTGGCTGACAGGTTTTGACGCCCCTTGTTGTAAT
ACAATGTATATCGACAAGCCGATGAAAGGGCATAATTTAATGCAGGCAATTGCCCGAGTAAACCGTGTTTTCCGCAATAA
AAGCCGTGAAAATGGTGGGTTAATTGTCGATTATGTGGGCTTGGTGGACGAACTTAAATCGGCAACGGCTGAATATACCA
ATGCAAATGGTAAGGGCGAAATGACGCAAGATATTGAGCAAATCAAACTCAAATTTTTAGAGTGCCTTGATATTGTGCGA
GGAATGTTTGCCAGCCCTGTAAGCGGCCAGATTTTTCCATTATTTGACGCATTAAAAATTCACGATGAAATGGCGTTATT
TGAGCAAATTCTAACGGCAGCAAACCATATTTTAAGCCTCGATCAGCAAAATCCTGTTGATGACAAAGCGAAGGATAAAA
CGCCACGCAAAAATCGCTTCTTGCAAGCGGTAAGATTAGCGAAAAAGGGTTACGGTTTGTGTGGTTCGTTGCCTGAAGTG
CAGGTTTATCAGCGAGAATTAGCGTTTATTGATGCGGTGCGAGCAATGCTTGCAAAACGTGAGCCAAATTCGACCGTTAA
CCCTGCCGACCGACAGCTTAAATTGGTGGCGTTGCTAAACCAAGCGGTAAAAGCCGATGGGGCAGTGGACTTATTTGCGT
TGCTTAATCGAGATCAGCCGAACATTGAGATTTTGTCGGAGCAGTTTTTAGAAAAAGTGAAAAATAGCCGCCACCAAGCG
TTGTGGCTTGAGGCGATTCAACGTTATCTGCAAGCGGAAATTAAGGAAAAAGGAGCGAGTAATCTTTCCGTGCAAAAAGA
TTTTGAAACTCGATTAAAAGAGGCGATGAATAAATATCGCAATCAAAATCTCACGTTACTTGAAATTTTGGACGAATTAT
TGGCAATGGGGAAAGAATTTGCCGAACGTTTGGCTCGTGGCGAAAAATTAGGGCTAACGCCTGCGGAAATCGCCTTTTAT
GACGCTTTGGCTCAAAACGAAAGTGCGGTGCGAGAATTAGGCGATGAAGTCTTGAAAAATTTGGCAATGACAATCACCGA
GAAGATCCGCCAATCTGCCACCATTGACTGGCAATTTAAAGATTCCGTGCGAGCCAAAATGCGAATTGAAATCCGCCGAG
CGTTAAGATTATTCAAATATCCGCCCGATAAACAAGTGGAAGCAGTTGAGTTTGTATTAAGACAAGCGGAAGTGATTGCC
GATGAATTAAGTTCACCTTAG

Protein sequence :
MHINENTIEQACIQALQGLGWAYTFGSEIERERAEEVVLKSVLANAITRLNPQLPSNVVNDVVALVCKGDITDLTERNQQ
FYRLLREGVQVEYRENDEQKIDIVRLIDFQNVHNNQFDVVNQFTIKGVKGNRRPDVICFVNGLPLVVFELKNPLTESADL
QQAFQQFQTYKAEISDLFVFNQALVISDGTHARIGSLTANFDRFTPWRVVDEKAKQRVPFENELAGLVQGLMSPENLLNY
VQNFVLFERSESGLLIKKIAAYHQFYGVNEAVESTLLAASEQGDRKIGVMWHTQGSGKSISMLFYAAKLQAEPSLRNPTI
VVVTDRNDLDGQLFATFSAGKDLIRQTPIQADGREALRTELAKRETGGIIFTTIQKFGLHEGENQHPILNDRHNIIVISD
EAHRSQYGFSQHLAMGTQSATYRVGYAKHLRNALPNASFIGFTGTPISLEDKDTQAVFGRYVSIYDIQDAVEDGATVPIV
YEARQIPINESQDFKNAVREADDLFSDDEQSYSFRLREKLIGADTRLTKLAEDLVKHFENRTALMDGKAMIVAMSRQICV
VLYDKIIALRPEWHSDNLNEGAIKIVMTGSASDPDHFQPHIYGNQEKKSLEKRFKDPSDPFKLVIVRDMWLTGFDAPCCN
TMYIDKPMKGHNLMQAIARVNRVFRNKSRENGGLIVDYVGLVDELKSATAEYTNANGKGEMTQDIEQIKLKFLECLDIVR
GMFASPVSGQIFPLFDALKIHDEMALFEQILTAANHILSLDQQNPVDDKAKDKTPRKNRFLQAVRLAKKGYGLCGSLPEV
QVYQRELAFIDAVRAMLAKREPNSTVNPADRQLKLVALLNQAVKADGAVDLFALLNRDQPNIEILSEQFLEKVKNSRHQA
LWLEAIQRYLQAEIKEKGASNLSVQKDFETRLKEAMNKYRNQNLTLLEILDELLAMGKEFAERLARGEKLGLTPAEIAFY
DALAQNESAVRELGDEVLKNLAMTITEKIRQSATIDWQFKDSVRAKMRIEIRRALRLFKYPPDKQVEAVEFVLRQAEVIA
DELSSP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
api52 CAF28526.1 hsdr-like Type I restriction enzyme Not tested YAPI Protein 0.0 49
hsdR BAH57699.1 type I restriction-modification system endonuclease homologue Not tested Type-VII SCCmec Protein 0.0 42
hsdR BAD24840.1 type I restriction-modification system endonuclease homologue Not tested Type-V SCCmec Protein 0.0 42
hsdR YP_251977.1 type I restriction-modification system restriction subunit Not tested SCCmec Protein 0.0 41